Apigenin: The Natural Sleep Aid You’ve Been Looking For

apigenin for sleep

Apigenin: The Natural Sleep Aid You’ve Been Looking For

Rising awareness about the health benefits of Apigenin and rising usage in the pharmaceutical and nutraceutical industries will accelerate market growth. Increasing consumer preference for natural and vegan cosmetics and personal care products has also increased the demand for Apigenin as an ingredient.

What Is The Current Market Demand For Apigenin In The USA?

As an FDA-approved dietary supplement ingredient, Apigenin is the most widely used in supplements. A study by Global Market Insights Inc reports that the apigenin market valuation is expected to exceed USD 400,000 by 2032. Key apigenin market players include Cayman Chemical Company, TCI Chemicals, ChemFaces, etc.

Apigenin’s antioxidant properties make it a popular ingredient in skincare products. It may be used in creams, lotions, or serums to provide antioxidant protection and support skin health.

New developments in the field of application of Apigenin

  • In 2022, Unity Biotechnology will enter into strategic cooperation with AbbVie. Development and commercialization of apigenin-based therapeutics for age-related diseases. This collaboration is a significant development for the apigenin business as it brings together two key players in the pharmaceutical industry.
  • In 2023, Phytopharm PLC signed a licensing agreement with Innocoll International to develop apigenin-based wound care products.

Classic Apigenin Formula

Apigenin achieves an anti-aging effect by inhibiting CD38 (cell membrane enzyme). When Apigenin is paired with NAD+ precursor NMN, the maximum NAD+ level increase can be achieved. Therefore, these two ingredients are considered anti-aging “golden partners.”

Apigenin is a naturally-sourced CD38 inhibitor, a flavonoid compound widely present in the plant kingdom. Apigenin can be found in various plant matter and herbs, such as chamomile, parsley, celery, and guava. Non-GMO, gluten-free, vegan-friendly product. Allergen free.

In addition to anti-aging, Apigenin also protects heart and brain health, promotes skin health, and alleviates anxiety. In addition, a new health benefit is slowly being discovered and paid attention to by the market.

Apply The Health Benefit Of Apigenin For Sleep Is A Trend.

Apigenin has been found to interact with certain receptors in the brain, potentially promoting relaxation and reducing anxiety. It may contribute to calmness and relaxation by calming the central nervous system, which can benefit sleep.

It has been shown to enhance the activity of GABA, an inhibitory neurotransmitter in the brain. GABA helps reduce neuronal excitability and promote relaxation, facilitating sleep onset and improving sleep quality.

Animal studies have suggested that Apigenin may increase total sleep time, decrease sleep latency and improve sleep quality. However, more research is needed to confirm it.

Apigenin vs Melatonin

Melatonin is a hormone. It naturally produces by the body’s pineal gland in response to darkness. It helps regulate the sleep-wake cycle and supports healthy sleep patterns. Melatonin also plays a crucial role in signaling the body to prepare for sleep and adjusting the internal body clock.

Apigenin vs Magnesium

Magnesium, as an essential mineral, helps with relaxation and sleep. It also involves various physiological functions. Among different types, Magnesium Glycinate and Magnesium Citrate are commonly regarded as recommended ingredients in dietary supplements for sleep. And Magnesium L-Threonate is a newer form of magnesium to enhance brain function and reduce anxiety. Some users report it can improve their sleep quality.

However, compared to Melatonin and Magnesium, Apigenin has calming effects on the central nervous system. It may interact with certain receptors in the brain. It also can contribute to relaxation and improve sleep quality.

The common and popular pure Apigenin specification is 98% pure bulk Apigenin powder HPLC. The latest market quotation from mainstream Apigenin suppliers is around $250-265/kg. (The price update on 2023/7/11)

Are There Any Specific Regulatory Requirements To Apply Apigenin Powder?

There are no specific regulatory requirements set by the FDA specifically for Apigenin as a standalone dietary supplement ingredient. It is a natural compound in certain plants and is GRAS for consumption.

However, it’s important to note that regulations and requirements can vary depending on the product formulation, intended use and claims about the product. If Apigenin is included as an ingredient in a dietary supplement or other product, the manufacturer must comply with the applicable FDA regulations for dietary supplements.

Dietary supplements, including those containing Apigenin, are regulated under the DSHEA in the United States.

What ingredients have interactions with Apigenin?

Apigenin has a mild sedative effect. Therefore, its calming effects may be enhanced with other calming ingredients. For example, valerian root extract, Lemon balm extract, Ashwagandha powder, etc.

And actually, because the FDA does not regulate Apigenin for specific health claims, there is no established standard dosage for this ingredient. Apigenin dosage is generally 50 mg-500 mg per serving as a dietary supplement ingredient.

Who Is The Best Pure Bulk Powdered Apigenin Supplier?

Nutri Avenue is a professional bulk powdered Apigenin supplier. We have five warehouses in the USA to stock our ingredients. It can support our customers more quickly and conveniently to get products.

How to control Apigenin powder quality by manufacturers?

  1. Nutri Avenue will strictly control Apigenin powder sources. The mainstream sales channels of Apigenin powder in the market are all manufactured by the semi-synthetic process of naringin. Therefore, Nutri Aveuen also chooses young pomelo fruit as the starting material.
    Of course, sources of Apigenin include chamomile, parsley, celery, etc. If the enterprise has a fixed source requirement, it can inform Nutri Avenue to realize it.
  2. In the manufacturing process, Nutri Avenue adopts the process of extraction and synthesis to prepare Apigenin powder to achieve a purity of 98%.
    The manufacturing cost is relatively high if this ingredient is simply extracted from plants. And its purity is difficult to reach 98%.
  3. During manufacturing, the FDA will comply with relevant regulatory standards and guidelines for dietary supplement ingredients. Moreover, all ingredients provided by Nutri Avenue, including Apigenin powder, have passed third-party quality inspections and obtained Kosher, Halal, GMP, and other qualification certifications to ensure that the raw materials purchased by the company in large quantities are safe and reliable.
  4. When enterprises purchase this ingredient, we can also provide COA, batch number, and other ingredient details to support your trust in the quality of our ingredients.

Share this post with your friends

Get a Free Quote

Stay In Touch

How can we help? Get free samples, pricing and stock list.

USA address
1641 W Main St, Ste 222, Alhambra, CA 91801
China address:
Room 209 , Huana Business Center , NO 1733 Lianhua Road , Minhang District , Shanghai , China 201103

Top Sellers

Nutri Avenue

how can we help ?

Bulk raw Ingredients Supplier

Nutri Avenue

Leave your details below, and let us help you get fresh, high-quality ingredients ASAP.