Vitamin Market: NAD+ May Become The Best Alternative to NMN

Due to regulatory issues surrounding NMN, many companies are shifting their focus to NAD+. It is reported that the market size for NAD+ is now almost as large as that of NMN. This market volume may suggest that NAD+ may become the best alternative to NMN.

Currently, the market price for NMN powder is approximately $99–110/kg, while its top alternative, NAD plus powder, is priced at $168–280/kg, showing significant price variation.

NAD Plus: The Best Alternative to NMN

NMN (β-Nicotinamide Mononucleotide) and NAD+ (Nicotinamide Adenine Dinucleotide) are essential molecules in the human body, playing key roles in energy metabolism and cellular repair. NMN serves as a precursor to NAD+, converting into it through biochemical processes. As a coenzyme critical for metabolism and DNA repair, NAD+ levels naturally decline with age, making supplementation with NMN or NAD+ a focus in the anti-aging industry.

Physical Properties Comparsion: NMN VS NAD Plus

NMN

• Highly hygroscopic; requires sealed storage.
• Soluble in water but has limited solubility in organic solvents like ethanol.
• Easily degrades under acidic or alkaline conditions, so it is best used in neutral environments.

NAD+

• Sensitive to light and heat; must be stored away from high temperatures and direct sunlight.
• Highly water-soluble but less stable in acidic or alkaline conditions.

NMN Regulatory Issues: Is NMN Banned By FDA?

• In the U.S.
  • In 2022, the FDA stated that NMN, due to its development as a potential pharmaceutical drug, is no longer considered a compliant dietary supplement ingredient. This has sparked debates about whether NMN can still be sold as a dietary supplement.
• In other countries
  • For instance, Japan has a more lenient stance on NMN, which is often marketed as a premium health food or cosmetic ingredient.

Functional Differences: NMN VS NAD Plus

• NMN: By supplementing NMN, the body boosts NAD+ levels, which helps enhance energy metabolism, antioxidant defense, and anti-aging processes. Its indirect action is more suitable for long-term regulation.
• NAD+: Acts directly as a coenzyme in biochemical reactions, providing faster effects. However, due to its large molecular size, it has low oral bioavailability and is typically administered via injections or specialized formulations for research and medical purposes.

The regulatory challenges surrounding NMN have accelerated the industry’s shift toward NAD+. While NAD+ commands a higher price, its growing demand and comparable market size reflect its potential as a preferred alternative. Companies are exploring new strategies to integrate NAD+ into their product lines, leveraging its direct benefits for anti-aging and cellular health.

Beyond the NMN and NAD+ markets, price stability in vitamins and other key supplements signals a balance period, with selective price shifts offering potential opportunities for strategic inventory decisions. Nutri Avenue remains committed to providing competitive pricing and high-quality raw materials tailored to diverse product development needs.

• Vitamin C Powder: $6-9/kg (The low-priced VC powder on the market has been nearly depleted. Future pricing is unlikely to drop below $5/kg, although manufacturers seem intent on maintaining stable prices. This product is worth keeping an eye on.)
• Ascorbic Acid Powder: $4.5-6/kg
• Vitamin C DC 97%: $6-8/kg
• Benfotiamine Powder: $65-74/kg
• D-Biotin Powder: $172-190/kg
• Vitamin B5 Powder: $10-12/kg
• Inositol Powder: $9-11/kg
• D-Chiro Inositol Powder: $285-300/kg
• Vitamin B2 Powder: $36-40/kg
• Vitamin B12 (Methylcobalamin) Powder: $2,100-2,300/kg
• Vitamin D3 (100,000 IU): $18-20/kg
• Natural Vitamin E (1,185 IU / 1,210 IU): $76-80/kg
• Vitamin K2 MK-4 Powder 1%: $110-123/kg
• CoQ10 Powder: $169-180/kg

Market Trends: Carnitines Powder

Nutri Avenue confirms a price increase in L-Carnitine Tartrate Powder, now at $22–24/kg. Other carnitine products to watch include:

• N-Acetyl L-Carnitine HCl Powder: $24–28/kg
• مسحوق ل-كارنيتين الأساسي: $26–30/kg

اتجاه أسعار مكونات المكملات الغذائية الشائعة في السوق

The prices of creatine monohydrate remain unchanged across the three major manufacturers. Given that the current prices are already very low, further significant price reductions are unlikely. Nutri Avenue believes there is a possibility of price increases for this product next year.

• Creatine monohydrate powder 200 mesh: $8–9.5/kg
• Creatine monohydrate powder 80 mesh: $9–11/kg

Prices of Other Popular Supplement Ingredients

• L-Theanine powder: $18–22/kg (clear signs of price increase)
• Sodium copper chlorophyll powder: $165–168/kg (prices decreased slightly compared to last week)
• Alpha lipoic acid powder/granular: $40–46/kg (stable trend)
• R-alpha lipoic acid powder: $238–255/kg
• CDP-Choline powder (Citicoline): $148–155/kg
• S-Adenosyl-L-methionine Disulfate Tosylate (SAMe) powder (98% purity): $150–168/kg
• DHA algal oil powder (20% purity): $44–49/kg
• Shilajit extract fulvic acid powder (20% and 50% purity options): $32–45/kg
• Green coffee bean 98% caffeine powder: $49–55/kg
• Alpha yohimbine powder 90%: $2,900–3,200/kg
• Natural Astaxanthin powder 1%: $64–69/kg
• Lycopene powder 5%: $92–99/kg
• Bitter melon extract powder (10:1/20:1): $11–13/kg
• Tribulus Terrestris powder extract (UV-tested; purity options 45%, 90%, and 95%): $14–17.5/kg

Promotional Supplement Ingredients List on Nutri Avenue

This list is valid from December 9, 2024, to December 15, 2024. It includes various types of products, such as amino acids, food additives, and plant extracts. These products support a wide range of applications, including sports nutrition, muscle building, and antioxidant benefits, making them adaptable to diverse product development and production needs.

Nutri Avenue offers the highest quality raw materials at the most competitive prices. Contact our sales team for the latest and most accurate quotes and product certifications. All our products are ISO-certified.

Note: The following are market reference prices, not promotional prices. For promotional pricing, please provide the quantity of your specific order.

• مسحوق بيتا ألانين: $4–4.5/kg
• Agmatine sulfate powder: $10–11/kg
• Gamma-Aminobutyric Acid (GABA) powder: $6–6.5/kg
• L-Citrulline powder: $9.5–11/kg
• N-Acetyl-L-Cysteine (NAC) powder: $14–16/kg
• Instant BCAA 2:1:1: $10–10.5/kg
• Zinc L-Carnosine powder: $245–260/kg
• Citicoline sodium powder: $145–150/kg
• Magnesium oxide powder/granular: $5.5–7.5/kg
• D-Mannose powder: $28–32/kg
• Bromelain powder 2,400 GDU/g: around $75/kg
• Bromelain 600 GDU/g: $20–26/kg
• Sucralose powder: $25.5–32/kg
• Fucoidan powder 85% (UV-tested): $85–88/kg
• Silybum marianum fruit extract (standard 70:1): $26–29/kg
• Milk Thistle Extract (80% Silymarin, 30% Silybin): $36–40/kg
• (This specification offers superior antioxidant, anti-inflammatory, and liver-protective effects compared to regular milk thistle extracts. Highly recommended.)

الخاتمة

The supplement ingredient market is seeing notable shifts, particularly in the pricing and demand for popular products like NAD+, NMN, and creatine monohydrate. While NAD+ has emerged as a preferred alternative to NMN due to regulatory challenges, creatine monohydrate prices remain stable but may increase next year. Meanwhile, other key ingredients, such as L-theanine and Alpha Yohimbine, show clear signs of price fluctuation, reflecting dynamic market trends. These changes highlight evolving industry priorities and growing consumer interest in functional ingredients that address health concerns like anti-aging, cognitive support, and fitness.

Nutri Avenue remains at the forefront of these trends, offering many high-quality supplement ingredients, from amino acids and vitamins to plant extracts. With ISO-certified products and competitive pricing, the company supports diverse applications, including sports nutrition, immune health, and antioxidant solutions. By closely monitoring market developments and maintaining responsive customer support, Nutri Avenue ensures clients can stay ahead in a competitive landscape while meeting the growing demand for innovative, science-backed health solutions.

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