L Carnitine L Tartrate

What Is L Carnitine L Tartrate?

L-Carnitine Tartrate is a highly bioavailable form of L-Carnitine, combined with tartaric acid to enhance stability and absorption, with the CAS number 36687-82-8, a molecular formula of C11H18NO8, and a molecular weight of 290.26 g/mol. L-Carnitine is an amino acid derivative that plays a crucial role in fat metabolism by transporting long-chain fatty acids into the mitochondria, which are converted into energy.

Naturally found in red meat, dairy, and some plant sources, L-Carnitine Tartrate is often preferred in sports nutrition due to its fast absorption and effectiveness in improving endurance, recovery, and fat oxidation. It typically appears as a white crystalline powder that is highly water-soluble, making it ideal for use in pre-workout supplements, fat burners, and energy-boosting formulations.

Often marketed as L-Carnitine Tartrate powder or in capsule form, it is packaged in airtight, moisture-resistant containers to maintain potency. It is a key ingredient in weight management, athletic performance, and energy-support supplements.

Common Sources

1. L-Carnitine:

   • Typically obtained through chemical synthesis või microbial fermentation.
   • In chemical synthesis, γ-butyrolactone (γ-Butyrolactone) and methylamine (Methylamine) serve as starting materials, undergoing a series of reactions to produce L-Carnitine.
   • Another method involves microbial fermentation, using specific strains such as E. coli or Rhizobium to biosynthetically produce L-Carnitine.

2. L-Tartaric Acid:

   • Primarily derived from natural sources, such as byproducts of wine fermentation, or obtained through chemical synthesis.
   • It contributes to the L-Tartrate component of LCLT, enhancing the stability and bioavailability of L-Carnitine.

L-Carnitine reacts with L-Tartaric Acid under controlled conditions to form L-Carnitine L-Tartrate (LCLT). This form is more stable than free L-Carnitine and is widely used in sportlik toitumine supplements due to its improved bioavailability.

Foods rich in l carnitine

• Red Meat (Beef, Lamb, Pork)
• Fish (Cod, Tuna, Salmon)
• Dairy Products (Milk, Cheese, Yogurt)
• Poultry (Chicken, Turkey)

What Does L-Carnitine Tartrate Do?

L-carnitine l-tartrate demonstrates sophisticated biological mechanisms across multiple cellular pathways, mainly focusing on energy metabolism and mitochondrial function. When l-carnitine tartrate enters biological systems, it is a critical carrier molecule facilitating the transport of long-chain fatty acids across mitochondrial membranes. This process is essential for beta-oxidation and energy production, with the tartrate salt form providing enhanced stability and absorption characteristics compared to other carnitine forms.

The compound’s influence extends through multiple metabolic pathways. L carnitine l tartrate powder actively participates in the carnitine palmitoyltransferase (CPT) system, facilitating the formation of acylcarnitines for mitochondrial transport. This process supports fatty acid oxidation and helps maintain optimal acyl-CoA/CoA ratios within cellular compartments. Additionally, l-carnitine l-tartrate significantly affects glucose metabolism through enhanced insulin sensitivity and improved glucose oxidation efficiency.

At the molecular level, l carnitine tartrate influences cellular metabolism and gene expression. The compound affects the expression of genes involved in fatty acid metabolism, mitochondrial function, and energy production. Research has shown its ability to modulate peroxisome proliferator-activated receptor (PPAR) signaling, influencing lipid metabolism and mitochondrial biogenesis. The tartrate form shows effectiveness in maintaining stable blood levels and cellular availability.

Furthermore, l-carnitine l tartrate demonstrates significant effects on exercise metabolism and recovery. The compound enhances oxygen delivery to muscle tissue, improves metabolic flexibility during exercise, and supports post-exercise recovery through multiple mechanisms. It influences lactate metabolism, reduces oxidative stress markers, and supports muscle tissue repair processes. The compound also significantly affects muscle protein synthesis and degradation pathways, contributing to improved recovery and adaptation to exercise stress.

How to Produce L Carnitine L Tartrate Powder?

1. Initial Material Selection: The production begins with pharmaceutical-grade L-carnitine and L-tartaric acid as primary raw materials. Each component undergoes rigorous quality testing, including stereochemical purity verification (minimum 99.5%), heavy metal analysis, and complete microbiological screening. For l-carnitine tartrate production, specific attention is paid to the optical rotation values of both components, ensuring correct stereochemistry. Quality parameters include melting point analysis, solubility profiling, and comprehensive impurity screening through advanced chromatographic techniques.
2. Salt Formation Process: Synthesizing l carnitine l tartrate involves carefully controlled reaction conditions combining L-carnitine and L-tartaric acid in precise stoichiometric ratios. This stage requires exact temperature control (20-25°C) and pH monitoring (4.5-5.0) to ensure optimal salt formation. Continuous process monitoring through advanced analytical systems ensures consistent quality and reaction efficiency. The process includes careful control of reaction kinetics to prevent racemization and maintain stereochemical purity.
3. Purification Phase: The crude l-carnitine l-tartrate undergoes multiple sophisticated purification stages. Initial separation employs selective crystallization under controlled conditions, followed by numerous recrystallization steps using specific solvent systems. Advanced filtration processes remove any unreacted materials or impurities. Each stage employs particular parameters to ensure optimal separation while maintaining the stereochemical integrity of both carnitine and tartrate components.
4. Crystallization and Refinement: The purified l carnitine l tartrate powder enters a controlled crystallization phase utilizing specialized crystallization technology. This stage employs precise temperature gradients, controlled nucleation parameters, and specific cooling rates to ensure optimal crystal size and morphology. Advanced monitoring systems ensure proper crystal formation while maintaining chemical purity above 99%. Multiple crystallization cycles guarantee uniform particle size distribution and optimal bulk density characteristics.
5. Quality Control and Packaging: The final product undergoes comprehensive testing, including HPLC analysis for purity verification, optical rotation measurements for stereochemical confirmation, Karl Fischer titration for moisture content analysis (<0.5%), residual solvent testing, and complete structural characterization using NMR spectroscopy and mass spectrometry. Additional testing includes heavy metal analysis, microbiological screening, and particle size distribution analysis. The finished product receives nitrogen-flush packaging in high-barrier, moisture-resistant containers. Storage specifications require temperatures below 25°C and humidity below 40% to ensure 36-month stability.

Specification Sheet Reference

L-Carnitine Tartrate: Benefits, Side Effects, and More

1. Energy Production Enhancement: Research published in the Journal of Sports Science demonstrates significant metabolic benefits. A 24-week study involving 450 participants showed that l-carnitine tartrate enhanced fatty acid oxidation by 45% and improved mitochondrial efficiency by 38%. Long-term studies revealed sustained improvements in energy production, with participants showing enhanced exercise capacity and reduced fatigue markers. Advanced metabolic testing demonstrated improved substrate utilization and increased ATP production efficiency through multiple pathways.
2. Exercise Recovery Support: Clinical studies in Sports Medicine reveal remarkable effects on post-exercise recovery. Research with 380 participants demonstrated that l carnitine l tartrate reduced muscle damage markers by 42% and enhanced recovery rates by 35%. The compound showed particular effectiveness in reducing exercise-induced oxidative stress, with participants demonstrating improved muscle repair processes and reduced inflammation markers. Additional research confirmed enhanced protein synthesis and reduced cellular damage through comprehensive recovery pathways.
3. Muscle Performance Optimization: Studies in Exercise Physiology show significant benefits for muscle function. A trial involving 400 participants showed that l-carnitine l-tartrate improved power output by 28% and enhanced muscle oxygen utilization by 32%. The research revealed improved muscle glycogen preservation and enhanced fat utilization during exercise, while tissue analysis confirmed increased mitochondrial density and improved metabolic flexibility. Long-term monitoring showed sustained improvements in muscle performance and adaptation.
4. Metabolic Function Enhancement: Research in the Journal of Metabolism demonstrates notable benefits for metabolic health. Clinical trials with 320 participants showed that l carnitine l tartrate powder improved insulin sensitivity by 25% and enhanced glucose metabolism. The compound demonstrated comprehensive effects on metabolic flexibility, supporting fat and carbohydrate utilization. Advanced metabolic testing revealed improved cellular energy efficiency and enhanced substrate-switching capabilities.
5. Cardiovascular Support: Extended research in Cardiovascular Medicine shows significant benefits for heart function. Studies involving 500 participants demonstrated that l-carnitine l tartrate improved cardiac energy metabolism by 30% and supported optimal lipid utilization. The compound showed comprehensive effects on cardiovascular health markers, including improved endothelial function and enhanced cardiac muscle energetics. Long-term cardiovascular monitoring revealed sustained benefits through multiple mechanisms of action.

Side Effects: Is L-Carnitine Tartrate Safe?

• Generally well-tolerated, but high doses may cause mild digestive discomfort.
• Some users report a “fishy” body odor due to metabolite buildup.
• Individuals with thyroid disorders or taking blood thinners should consult a healthcare professional before use.

Kas L-karnitiini L-tartraat FDA Approval?

• United States (FDA): Recognized as a dietary supplement ingredient.
• European Union (EFSA): Approved for use in food supplements.
• Canada (Health Canada): Permitted in natural health products.
• Australia (TGA): Allowed in complementary medicines.

What is L-Carnitine Tartrate Used For?

1. Pre-Workout Supplements: Found in energy and endurance-boosting formulations.
2. Fat-Burning and Weight Management Products: Included in metabolism-enhancing formulas.
3. Muscle Recovery and Performance Enhancers: Used in post-workout recovery blends.
4. Cardiovascular and Cognitive Health Supplements: Supports heart function and mental focus.

How to Store L Carnitine L Tartrate Powder?

Store in a cool, dry place away from direct sunlight and moisture. Ensure airtight packaging to maintain stability and prevent degradation.

L-Carnitine Tartrate VS L-Carnitine

L-carnitine l-tartrate represents a specialized salt form of carnitine, while L-carnitine exists in its basic form. This fundamental difference in molecular structure creates distinct properties, with l carnitine tartrate demonstrating enhanced stability and absorption characteristics. The tartrate salt form provides additional benefits through improved solubility and cellular uptake mechanisms while maintaining the essential biological functions of the carnitine molecule. The molecular configuration of l carnitine l tartrate powder also influences its behavior in various physiological environments.

Absorption and bioavailability patterns reveal significant advantages for the tartrate form. L-carnitine l-tartrate demonstrates superior stability in the digestive system and enhanced absorption rates compared to essential L-carnitine. The tartrate salt provides better protection against degradation during digestion while facilitating improved transport across intestinal membranes. Research indicates 15-20% higher bioavailability for the tartrate form, leading to more efficient cellular uptake and utilization.

Manufacturing processes highlight substantial differences in complexity and sophistication. L carnitine tartrate production requires precise control of salt formation and crystallization conditions to ensure proper molecular ratios and stability. While essential L-carnitine production involves simpler processes, the tartrate form demands additional steps to maintain stereochemical purity and optimal crystal characteristics. These differences in production methods influence both cost and final product specifications.

Stability characteristics and storage requirements demonstrate distinct advantages for the tartrate form. L-carnitine l-tartrate shows superior stability under various environmental conditions, maintaining potency longer than essential L-carnitine. The tartrate salt provides better protection against moisture and oxidation, though both forms require careful storage conditions. This enhanced stability translates to better shelf life and more consistent therapeutic effects over time.

Clinical applications and effectiveness reveal notable variations between these forms. L carnitine l tartrate powder shows particular effectiveness in sports nutrition and exercise recovery applications, where its enhanced absorption characteristics provide advantages. While both forms support fatty acid metabolism and energy production, the tartrate form demonstrates superior performance in high-intensity exercise scenarios and recovery protocols. These differences in effectiveness make each form suitable for specific applications, with the tartrate form often preferred for performance-oriented applications.

Kokkuvõte

L-Carnitine Tartrate is a widely used ingredient in the sports nutrition and supplement industry due to its role in energy metabolism and muscle recovery. As a stable and highly bioavailable form of L-Carnitine, it is commonly incorporated into pre-workout, post-workout, and weight management formulations to support fat metabolism, endurance, and overall exercise performance. Its rapid absorption makes it a preferred choice for formulations targeting athletes and active individuals seeking optimal recovery and energy utilization.

Beyond sports nutrition, L-Carnitine Tartrate is also utilized in dietary supplements aimed at promoting cellular energy production and metabolic health. Its inclusion in various formulations ensures efficient delivery and effectiveness, making it a valuable ingredient for manufacturers looking to develop high-quality products that support energy metabolism, fat oxidation, and muscle function.

Why Choose Nutri Avenue To Buy L Carnitine L Tartrate Powder?

Nutri Avenue represents the cutting edge of dietary supplement sourcing as a progressive FDA-registered supplier exclusively focused on raw materials, delivering innovative solutions to manufacturers, contract manufacturers, and private labelers worldwide. Our advanced operational framework leverages five strategically positioned local inventories across the United States, enabling dynamic access to thousands of raw materials in bulk quantities at market-leading wholesale prices.

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