Everything About Fisetin You Should Know 2024

Fisetin sources

The global anti-aging market is expected to grow to around USD 22 billion by 2023 amidst the value economy and aging population. With the rapid development of the anti-aging market, the Fisetin market space will continue to expand. Currently, it is relatively stable, but overall, it is a growing trend.

Fisetin is known as the focus of scientific research due to its unique chemical structure and superior biological activity. It has antioxidant, anti-inflammatory, anti-tumor, and anti-aging properties.

What Is Fisetin?

Fisetin is a flavonol, a type of flavonoid. It is also a naturally occurring polyphenol compound. It is also found in a variety of fruits and vegetables, such as strawberries, apples, persimmons, grapes, onions, and cucumbers.

Scientists have known about the substance for almost 200 years, since 1833, when it was first isolated from the Venetian lacquer tree plant. But, it wasn’t until 2018 that research on the ingredient entered the realm of anti-aging and longevity. At that time, it was recognized as an anti-aging therapeutic agent or a substance that destroys senescent cells.

Nutri Avenue offers Fisetin. It is extracted from Cotinus coggygria Scop., a polymeric pharmaceutical ingredient. The CAS number is 528-48-3, and the molecular weight is 286.24 g/mol. Fisetin has a predominantly yellow powder appearance.

Fisetin Benefits For

Brain(Neuroprotective Properties)

It improves long-term memory and increases concentration. Its natural substances have various effects on the human body.


It eliminates damaged or senescent cells, thereby reducing susceptibility to age-related diseases. It directly slows down the effects of aging. On the other hand, this natural substance prevents cells from entering a damaged state.

Bone Health

Lacin is also used to treat osteoporosis. The natural active ingredient both stimulates the activity of osteoblasts and prevents them from differentiating into osteoclasts and inhibiting their activity. In turn, it has a positive effect on bone density.

About Fisetin Dosage

Human studies on Fisetin have been conducted, and all have used a daily dose of 100 milligrams.

Some studies mention that laccasein slows skin aging by removing senescent cells and attenuating the senescence-associated secretory phenotype (SASP) in aging skin. For example, a study conducted by Japanese scholars confirmed that lacin can improve skin aging by selectively removing senescent cells in the skin and inhibiting SASP.

According to another study, mammals regularly supplemented with 100mg/kg of Fisetin could remove 90% of their aging cells within 28 days and clearly showed “youthfulness” regarding their appearance.

Therefore, this dosage is based on extensive animal data showing efficacy and safety, as well as human dosage according to FDA guidelines.

How To Order Large Quantities Of Fisetin Worldwide?

The ingredient is manufactured in various countries, including China, India, Europe, and the United States.

First of all, China, as a big producer of Fisetin powder, has abundant raw material resources and a mature production process. The product quality is stable and reliable. The international market well recognizes it.

Secondly, India’s unique production technology and lower composition make its products competitive internationally.

Finally, Europe and the United States are relatively small in production scale. However, their R&D strength and innovation ability are stronger. The quality and technical content of the products are higher.

And, Nutri Avenue fulfills all the above advantages. Our Fisetin Powder is characterized by its natural extraction, high purity, high stability, and high production volume, which meets the research and production of dietary supplements, skin care products, and promotional products in various parts of the world, including North America, South America, UK, France, Mexico, Poland, etc.

How To Test Powder Quality?

Fisetin powder is generally tested in two ways.

The first is the area normalization method. This method is based directly on the percentage of peak area occupied by the liquid phase. Usually, the system will show it at the bottom of the graph.

The other way is called the external standard method. It involves weighing the sample and the size of the peak area and then calculating it based on a formula.

The 98% purity of Fisetin powder offered by Nutri Avenue, as detected by the area normalization method, is actually equal to 85% under the external standard testing method. On top of that, we have a medium purity option at 50%. This natural substance is mainly sold commercially in the form of capsules.


Numerous studies have shown that lacinin extracts exhibit great potential and broad prospects in biomedicine, health care, and other fields. Meanwhile, it is noteworthy that this ingredient has shown steady growth in the international market. But, at present, its market offer is still stable. Welcome to contact us for more Fisetin information.

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