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What Is Radix Polygalae Extract？
It is a natural substance derived from the roots of the Polygala plant, scientifically known as Polygala tenuifolia. Radix Polygalae Extract is frequently utilized in traditional Chinese medicine due to its therapeutic attributes. It contains active compounds such as triterpenoid saponins, including tenuifolin and polygalasaponins, which are believed to contribute to its therapeutic effects.
Radix Polygalae extract is known for its potential neuroprotective, memory-enhancing, and anti-inflammatory properties, making it a subject of interest in research and health applications.
Active Ingredients In Radix Polygalae
Radix Polygalae, containing these active ingredients, holds promise in natural medicine, offering potential therapeutic effects for cognitive health and inflammation-related conditions.
- Tenuifolin. It is a triterpenoid saponin found in Radix Polygalae. It is renowned for its neuroprotective properties, potentially enhancing cognitive function and memory retention. Additionally, tenuifolin exhibits anti-inflammatory effects, contributing to its therapeutic benefits.
- Polygalasaponins. They are another group of triterpenoid saponins present in Radix Polygalae.
These compounds are related to various health advantages, such as neuroprotective impacts and possible enhancements in cognitive abilities. Additionally, polygala saponins exhibit anti-inflammatory properties, which may contribute to their role in promoting overall health and well-being.
What Is Saponins?
It is a class of natural organic compounds widely found in the plant kingdom. They belong to glycosides and have unique foaming properties.
Saponins are usually composed of sapogenin and sugar molecules. Among them, sapogenin can be triterpenoids or spirostanols compounds.
It gets its name from its foaming properties. This property made them used as detergents in ancient times. In Latin, “Sapo” means soap. It reflects their similarity to soap.
Saponins have various ecological functions in plants, including helping plants resist pathogens and pests as part of the plant’s defense mechanism. In addition, this organic compound is also used in the pharmaceutical and food industries. They are believed to have a variety of biological activities, such as antibacterial, antipyretic, soothing, and anti-cancer.
In traditional Chinese medicine, saponins are the main active ingredients of many plants, such as ginseng extract, polygala tenuifolia, Platycodon, Licorice, Anemarrhena, and Bupleurum. Their appearance can be white to light yellow-brown powder or tea brown to brown-black paste. Its solubility in water depends on its specific chemical structure. But usually, they can form colloidal solutions in water and show excellent foaming and emulsifying effects.
Specitification Sheet Reference
| Tyyppi | Kasviuute |
| Ulkonäkö | Fine brownish powder |
| Puhtaus | 20% saponins (common range: 5% to 50% for specialized extracts) |
| Sertifikaatit | ISO, Kosher, Halal, etc. |
| Aktiivinen ainesosa | Saponiinit |
| Testimenetelmät | High-Performance Liquid Chromatography (HPLC), UV Spectroscopy |
| MOQ (vähimmäistilausmäärä) | 1kg |
| Näyte | Saatavana (10-20g/säkki) |
| OEM-palvelu | Saatavilla, kuten kapselit, tabletit, pillerit jne. |
| ODM-palvelu | Saatavilla |
| Yksityinen tuotemerkki | Saatavilla |
| Sopimusvalmistus | Saatavilla |
General Radix Polygalae Extract Production Process
- Collecting mature Polygala roots.
- Thoroughly removing impurities.
- Using methods like air drying.
- Grinding or milling for increased surface area.
- Using solvents like water or ethanol.
- Removing insoluble particles.
- Increasing compound concentration.
- Optional step for enhanced purity.
- Removing remaining solvent.
- Ensuring consistency and purity.
- Storing in appropriate conditions.
Radix Polygalae/Polygala Tenuifolia Extract: Benefits, Applications, And More
This extraction, derived from the roots of Polygala species, has garnered attention for its potential health benefits. Abundant in bioactive components, this extract has a history of traditional herbal medicine usage and is currently under scientific investigation.
- Active ingredients in Polygala tenuifolia root Extract may support cognitive function, memory, and learning.
- It may possess anti-inflammatory effects, potentially alleviating inflammation-related conditions.
- Radix polygalae extract offers neuroprotective properties, potentially guarding against neurological disorders.
- It may exhibit anxiolytic and antidepressant properties, aiding mood-related issues.
- Studies suggest Polygala tenuifolia may enhance sleep quality and regulate sleep patterns.
- Its antioxidants combat oxidative stress, reducing chronic disease risks.
- It may benefit heart health, reducing cardiovascular disease risks.
- Traditional use and preliminary studies suggest Radix Polygalae aids digestion and relieves gastrointestinal discomfort.
- It may promote anti-aging benefits with its antioxidant and neuroprotective effects.
- Utilized for centuries in traditional medicine, it is under study for modern therapeutic applications
FDA-Approved: Yes Or No?
Radix Polygalae Extract is not FDA-approved as a standalone medication or supplement. It has been involved in clinical trials and research activities, but this does not constitute FDA approval for public market use.
However, the policy approval situation for the main active ingredients in the Polygala tenuifolia root plant, the saponins, is slightly clearer. Yucca plants are a valuable source of steroidal saponins and are approved as GRAS by the FDA. They are widely used in beverages, animal feed, cosmetics, and agriculture.
However, it is important to note that not all types of saponins are classified as GRAS. The GRAS status of saponins depends on various factors, including their chemical structure, source, dosage, and specific use in food. Therefore, not all saponins are considered generally safe. Especially in high concentrations, they may adversely affect the gastrointestinal system.
While some specific saponins are listed as GRAS by the FDA, not all saponins enjoy this status. When using saponins as food additives, you must ensure they meet the FDA’s safety standards and regulations.
If you are interested in Radix Polygalae extract and saponins, contact our sales team to discuss the details.
Buy Polygala Tenuifolia Root Extract On Nutri Avenue
Nutri Avenue is your trusted supplier for manufacturers seeking premium Radix Polygalae Extract. We offer a reliable source of high-quality extract sourced from reputable manufacturers.
With our dedication to superior quality and rigorous quality assurance protocols, rest assured that our Radix Polygalae Extract conforms to the highest benchmarks set by the industry. Partner with Nutri Avenue for seamless procurement and access to top-tier ingredients for your manufacturing needs.
UKK
It can cause mild nausea and, if taken in larger doses, may lead to nausea, vomiting, abdominal distension, diarrhea, and adverse reactions of hemolysis.
Polygalae Extract may interact with certain medications or supplements, particularly those affecting neurotransmitter levels or blood clotting.
Yes. It is typically derived from plant sources and is ideal for vegetarians and vegans.
