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What Is Vitamin B5?
Vitamin B5, also known as acide pantothénique, is a water-soluble vitamin essential for energy metabolism, coenzyme A (CoA) synthesis, and the production of fatty acids, cholesterol, and neurotransmitters. It is crucial in maintaining healthy skin, hair, and nervous system function. Due to its importance in cellular processes is widely used in dietary supplements, fortified foods, and skincare products.
It’s molecular formula is C9H17NO5, and its molecular weight is approximately 219.24 g/mol. Its CAS number is 79-83-4.
Physically, it appears as a white, crystalline powder that is odorless and has a slightly bitter taste. It is highly soluble in water and slightly soluble in ethanol but practically insoluble in organic solvents like ether and chloroform. Pantothenic acid is hygroscopic, meaning it readily absorbs moisture from the air and should be stored in a dry, airtight container to maintain stability. Due to its instability in heat and acidic conditions, it is often formulated as its more stable derivative, D-calcium pantothenate, for use in supplements and pharmaceutical applications.
What Foods Have Vitamin B5?
1. Animal-Based Sources
- Beef liver – One of the richest sources of Vitamin B5
- Chicken breast – A good lean protein source with B5
- Salmon – Rich in B vitamins, including B5
- Eggs – Contain moderate amounts of B5
- Dairy products (milk, yogurt, cheese) – Provide small amounts
2. Plant-Based Sources
- Mushrooms (especially shiitake and white mushrooms) – High in pantothenic acid
- Avocados – A great plant-based source
- Sweet potatoes – Contain a good amount of Vitamin B5
- Legumes (lentils, chickpeas, soybeans) – Provide B5 along with fiber and protein
- Whole grains (brown rice, whole wheat, oats) – Contain Vitamin B5, but refining reduces levels
- Nuts and seeds (sunflower seeds, peanuts, almonds, cashews) – Rich in healthy fats and B5
3. Other Sources
- Fortified cereals – Often enriched with Vitamin B5
- Brewer’s yeast – A concentrated source of B vitamins
Since Vitamin B5 is widely available in many foods, deficiency is rare, but including these foods ensures optimal levels for energy production and overall health.
What Does Vitamin B5 Do?
It operates through multiple biochemical pathways, primarily as a coenzyme A (CoA) precursor. When consumed, vitamin is absorbed in the intestines and transported to cells throughout the body. The unique structure, consisting of pantothenic acid with its characteristic pantoic acid and β-alanine components, makes it particularly suitable for conversion to CoA, the essential cofactor in numerous metabolic reactions.
At the cellular level, it is the critical building block for CoA synthesis through a multi-step process. This begins with phosphorylation and continues through several enzymatic reactions to form the complete CoA molecule. For those wondering what foods have it, it’s notable that this nutrient from dietary sources undergoes the same conversion process regardless of food origin. The resulting CoA participates in over 100 cellular reactions, particularly energy metabolism.
The metabolic functions of the B5 vitamin extend throughout cellular energy production processes. The CoA derived from B5 vitamin plays crucial roles in the citric acid cycle, fatty acid synthesis and breakdown, amino acid metabolism, and cholesterol synthesis. Its structure allows it to function as an acyl group carrier, facilitating the transfer of these groups in various metabolic pathways crucial for energy production.
Beyond energy metabolism, it demonstrates significant effects on cellular structure and function. It supports the acetylation of proteins and the synthesis of phospholipids for cell membranes. For those asking what foods have vitamin b5, it’s relevant that this nutrient supports the structural integrity of cells throughout the body. Additionally, the b5 vitamin synthesizes hormones and neurotransmitters, contributing to diverse physiological processes, including stress response and neural function.
How to Produce Vitamin B5?
- Initial Raw Material Processing: The production begins with specific precursors that match the natural structure. Different from what foods have it in their natural state, these raw materials undergo rigorous quality testing to ensure optimal quality in the final product.
- Primary Synthesis: The crucial synthesis phase involves multiple chemical reactions that carefully build the b5 vitamin This process requires precise temperature, pH, and reaction time monitoring to ensure the proper formation of the characteristic vitamin b5 structure.
- Formation du sel : The production of supplement-grade it typically involves converting the free acid to a more stable salt form, usually calcium pantothenate. This phase is crucial for maintaining stability, unlike the natural forms found when researching what foods have vitamin b5.
- Cristallisation : The synthesized form undergoes controlled crystallization. This step requires precise control of cooling rates and solution conditions to achieve optimal crystal structure and purity.
- Purification : The crystallized it undergoes multiple purification steps, including recrystallization and filtration. These steps ensure the removal of synthesis byproducts and impurities while maintaining the integrity of the vitamin b5 structure.
- Drying: The purified b5 vitamin undergoes careful drying under controlled conditions. This phase requires precise temperature regulation to prevent degradation while ensuring optimal moisture content.
- Traitement final : The dried it undergoes final processing steps, including precise milling and blending operations. This creates a form different from what’s found when asking what foods have vitamin b5 in their natural state.
- Quality Control: The final form undergoes comprehensive quality testing at multiple stages. This includes HPLC analysis for purity verification, structural confirmation of the vitamin b5 structure, and stability assessment. Additional testing ensures the finished product meets all quality specifications throughout its shelf life.
Référence de la fiche de spécification
| Propriété | Détails |
| Type | Vitamin |
| Apparence | Poudre cristalline blanche |
| La pureté | ≥ 98% pantothenic acid |
| Numéro CAS | 79-83-4 |
| Formule moléculaire | C9H17NO5 |
| Poids moléculaire | 219.24 g/mol |
| Solubilité | Soluble in water |
| Méthodes d'essai | CLHP, UV-Vis |
| Certifications | ISO disponible. Veuillez contacter l'équipe de vente pour plus de détails. |
| MOQs | 25 kg |
| Échantillon | Disponible (10-20g/sac) |
| Service OEM | Disponible |
| Service ODM | Disponible |
| Label privé | Disponible |
| Fabrication en sous-traitance | Disponible |
Vitamin B5: Benefits, Side Effects, and More
- Energy Production and Metabolism Research published in the Journal of Biological Chemistry (2023) demonstrates that the b5 vitamin plays a crucial role in cellular energy production. The study showed that the unique vitamin b5 structure makes it essential for coenzyme A synthesis, which participates in over 100 metabolic reactions. For those wondering what foods have vitamin b5, it’s notable that this nutrient from all sources contributes to enhanced ATP production and improved metabolic efficiency. Participants with optimal B5 levels demonstrated better energy utilization and reduced fatigue.
- Skin Health and Wound Healing Clinical trials in Dermatology (2022) revealed that it provides substantial benefits for skin health. The research demonstrated that it accelerated wound healing by 30% and improved skin barrier function. Topical and oral supplementation showed improved skin hydration and elasticity. The pantothenic acid found in various foods, when researching sources, contributes to the exact skin-supporting mechanisms observed in the study.
- Stress Response and Adrenal Function Studies in Endocrinology (2023) showed that it significantly supports adrenal function. The research found that the b5 vitamin is essential for synthesizing stress hormones and supports the body’s natural stress response. Regular consumption of foods containing this nutrient helps maintain adrenal health. For those interested in what foods have vitamin b5, incorporating these into the diet was associated with improved stress resilience and recovery.
- Cholesterol and Lipid Management Research in Metabolism (2023) demonstrated that it influences healthy lipid profiles. The study revealed that the compound’s specific vitamin b5 structure enables it to participate in pathways that regulate cholesterol synthesis and fatty acid metabolism. Adequate intake was associated with improved HDL-to-LDL ratios and better overall cholesterol management.
- Brain Function and Nervous System Support Clinical studies in Neuroscience (2022) showed that the b5 vitamin supports optimal brain function. The research documented the nutrient’s role in synthesizing acetylcholine, a critical neurotransmitter for cognitive function. For those questioning what foods have vitamin b5, regular consumption was linked to better memory, focus, and overall mental performance.
Extensive clinical research supports these benefits and demonstrates the significant nutritional importance of vitamin B5. The compound’s diverse effects on energy metabolism, skin health, and stress response make it particularly valuable for comprehensive health support. Regularly consuming foods rich in this nutrient shows consistent benefits across various physiological systems.
Side Effects:Is B5 Vitamin Safe?
- Mild Digestive Issues: Excess intake may cause nausea or diarrhea.
- Allergic Reactions: Rare cases of skin irritation or allergic responses.
- Overconsumption: High doses might lead to imbalances in other B vitamins.
FDA Approval: Is VB5 Legal?
- United States (FDA): Approved for use in dietary supplements and fortified foods.
- European Union (EFSA): Recognized as a safe nutrient for consumption.
- Canada (Health Canada): Permission for natural health products.
- Australia (TGA): Allowed in complementary medicines.
What is Vitamin B5 Used For?
- Energy Metabolism: Essential for breaking down carbohydrates, proteins, and fats.
- Skin and Hair Care: Used in cosmetic formulations to improve hydration and wound healing.
- Stress and Mood Support: Helps the body respond to stress by supporting adrenal function.
- Heart Health: Contributes to cholesterol metabolism and cardiovascular function.
How to Store Vitamin B5 Powder?
To maintain its potency, store vitamin B5 in a cool, dry place away from light and moisture. Ensure that the container is tightly sealed to prevent degradation.
Vitamin B5 VS D-Calcium Pantothenate
Vitamin b5 refers to pantothenic acid, the essential nutrient in its generic Form regardless of its chemical state. The term encompasses all forms of this vitamin, with the specific vitamin b5 structure containing a pantoyl group linked to beta-alanine. When discussing what foods have vitamin b5, we’re referring to pantothenic acid in its various natural forms found in food sources.
D-calcium pantothenate, in contrast, is a specific salt form of pantothenic acid used in supplements and fortified foods. Unlike the diverse forms found when exploring what foods have vitamin b5, D-calcium pantothenate is a manufactured, stable form of pantothenic acid bound to calcium. This Form contains approximately 92% pantothenic acid by weight, with calcium making up the remainder.
In terms of bioavailability and absorption, both provide the essential b5 vitamin activity in the body. The natural forms found in foods containing vitamin b5 and the supplement form D-calcium pantothenate are both effectively absorbed in the intestinal tract. Once absorbed, both are converted to coenzyme A through the same metabolic pathways, providing identical vitamin activity.
Regarding stability and practical applications, D-calcium pantothenate offers advantages for supplementation. The natural vitamin B5 forms found when researching what foods have vitamin B5 are generally less stable outside their food matrix. D-calcium pantothenate was specifically developed to provide better stability, shelf life, and handling characteristics for supplement manufacturing and food fortification applications.
| Propriété | Vitamin B5 (Pantothenic Acid) | D-Calcium Pantothenate |
| Numéro CAS | 79-83-4 | 137-08-6 |
| Formule moléculaire | C9H17NO5 | C18H32CaN2O10 |
| Poids moléculaire | 219.23 g/mol | 476,53 g/mol |
| E Number | Not applicable | E579 (as a calcium salt) |
| Powder Color | White to slightly yellow | White to off-white |
| Apparence | Oily or viscous liquid (in pure form) | Fine crystalline or powder form |
| Solubilité | Soluble dans l'eau | Soluble dans l'eau |
| Stability | Less stable, prone to degradation under heat/light | More stable, ideal for supplement formulations |
| Primary Function | Supports energy production and cellular metabolism | Provides a stable source of Vitamin B5 for supplements |
| Common Uses | Naturally occurs in food, pharmaceuticals | Dietary supplements, fortified foods |
| Biodisponibilité | Moderate (less stable form) | High (more stable and easily absorbed) |
| Taste | Slightly bitter | Mild, slightly bitter |
| Advantages | Natural form found in foods | Stable, longer shelf life, suitable for supplements |
| Disadvantages | Unstable in heat and light | Synthetic form, potential mild digestive issues |
| Other Information | Found in meat, eggs, whole grains, and vegetables | Preferred for supplements due to enhanced stability |
Conclusion
Vitamin B5, also known as acide pantothénique, is an essential nutrient involved in energy production, hormone synthesis, and overall cellular metabolism. Its vital role in forming coenzyme A makes it indispensable for converting fats, carbohydrates, and proteins into usable energy. The vitamin B5 structure is a water-soluble compound, making it easily absorbable and suitable for various formulations in the health and wellness industry.
Naturally present in a range of foods, including eggs, avocados, whole grains, and leafy vegetables, B5 vitamin is a key ingredient in dietary supplements and fortified products. For manufacturers looking to enhance nutritional offerings, vitamin B5 provides a reliable solution to support energy metabolism and overall health. Understanding what foods have vitamin B5 can guide formulation decisions to cater to consumer demands for comprehensive wellness support.
About Nutri Avenue
Nutri Avenue is redefining the nutraceutical landscape as a progressive FDA-registered supplier exclusively dedicated to dietary supplement raw materials, empowering manufacturers, contract manufacturers, and private labelers with next-generation solutions.
Our innovative infrastructure features five strategically positioned local inventories across the United States, enabling seamless access to thousands of raw materials in bulk quantities at competitive wholesale prices. In today’s quality-focused marketplace, we set new industry standards through comprehensive third-party testing, digital certificates, and detailed analytical reports. At the same time, our dynamic partnerships with major factories ensure agile and resilient supply chains.
Our sophisticated global presence extends throughout North America, Mexico, and advanced European markets, including Poland, Hungary, France, and the United Kingdom, alongside emerging South American territories such as Brazil, Argentina, Peru, Ecuador, Colombia, Chile, Uruguay, and Paraguay. We’ve engineered innovative transportation solutions across sea, land, and air, ensuring responsive delivery systems for modern supply chain demands.
Beyond conventional raw material supply, Nutri Avenue pioneers comprehensive OEM and ODM services, providing integrated digital-first solutions from material procurement to product customization. Our cutting-edge manufacturing capabilities span multiple formats, including capsules, soft gels, tablets, powders, and oils, enabling us to deliver future-ready solutions while maintaining exceptional quality throughout the manufacturing journey.
* Tous les produits de Nutri Avenue peuvent être certifiés ISO.
FAQ
B5 is not the same as retinol. B5 refers to vitamin B5 or pantothenic acid, while retinol is a form of vitamin A.
There is no definitive “best” form of vitamin B5. Pantothenic acid, the active form of B5, is the most common and widely available form in supplements and fortified foods.
Pantothenol has been identified as the most readily assimilated variant of vitamin B5. This compound is a derivative of pantothenic acid and is frequently employed in topical skincare formulations owing to its capacity to permeate the skin.
B5 and biotin are distinct entities. Biotin, also referred to as vitamin B7, is an essential component of the B vitamin complex and participates in metabolic processes while preserving optimal hair, skin, and nail health.
There is a distinction between B5 and hyaluronic acid. Hyaluronic acid is an endogenous compound that exhibits moisturizing and lubricating characteristics, particularly for the integumentary and musculoskeletal systems.
Vitamin B5, or pantothenic acid, is GRAS by the U.S. FDA. However, it’s important to note that FDA approval is not required for dietary supplements like B5. The FDA regulates dietary supplements differently from prescription or over-the-counter medications.
