4-Hydroxy-3-Methoxybenzylamine HCL Controls Inflammation and Prevents Development of Cancer Cells.
What Is 4-Hydroxy-3-Methoxybenzylamine Hydrochloride?
4-Hydroxy-3-Methoxybenzylamine Hydrochloride is a chemical compound derived from benzene. It features hydroxyl, methoxy, and amine groups attached to its molecular structure. The hydrochloride salt form of this compound improves its stability and water solubility. It’s often used as a precursor in synthesizing more complex molecules, particularly in the pharmaceutical industry.
Properties
Quality Level | 200 |
Assay | 98% |
mp | 219-221 °C (dec.) (lit.) |
SMILES string | Cl.COc1cc(CN)ccc1O |
InChI | 1S/C8H11NO2.ClH/c1-11-8-4-6(5-9)2-3-7(8)10;/h2-4,10H,5,9H2,1H3;1H |
InChI key | PUDMGOSXPCMUJZ-UHFFFAOYSA-N |
Bulk 4-Hydroxy-3-Methoxybenzylamine HCL Sources
Common Specifications
Type | 4-Hydroxy-3-Methoxybenzylamine HCL |
Appearance | White or off-white crystalline powder |
Purity | >98% |
Assay (argentometric) | 98.0% – 102.0% |
Melting range (lower value) | 180°C (approximate) |
Melting range (upper value) | 185°C (approximate) |
Identity (IR) | Conforms |
Certifications | Kosher, Halal, GMP, etc. |
Active Ingredient | None |
Test Methods | HPLC, Titration, IR Spectroscopy |
MOQ (minimum order quantity) | 1kg |
Sample | Available (10-20g/bag) |
OEM Service | Available, such as capsules, tablets, pills, etc. |
ODM Service | Available |
Private Label | Available |
Contract Manufacturing | Available |
How Does It Work?
4-Hydroxy-3-Methoxybenzylamine HCl acts on several systems in the body. Firstly, it interacts with receptors related to neurotransmitters like serotonin, dopamine, and norepinephrine. This interaction suggests it might have a role in regulating mood and pain perception, though researchers are still investigating the exact details. Secondly, this compound targets the TRPV1 receptor, an ion channel on sensory neurons that plays a role in sensing pain and temperature. Activating TRPV1 can potentially desensitize these neurons, leading to a possible reduction in pain signals.
Potential Health Benefits of 4-Hydroxy-3-Methoxybenzylamine HCL
Higenamine is a compound that has been investigated for its potential health benefits.
1.Pain Management
Its interaction with the TRPV1 receptor presents the most concrete possibility for health benefits. It suggests a potential role in treating various types of pain, especially chronic pain conditions.
2.Mood Regulation
Due to its effects on neurotransmitters like serotonin and dopamine, there’s speculation that it could have applications in managing mood disorders. However, the research on this is less established.
3.Other Investigational Areas
Researchers also explore its potential in inflammation and nerve health conditions.
Industry Applications and Research
It has found its way into some pre-workout and fat-burning supplements. Still, its use in this industry remains controversial due to questions about its safety and whether it works. It also has roots in traditional Chinese and Japanese medicine, though its historical uses may differ from the areas researchers are focused on today. The most promising research surrounds its potential for pain management due to its effects on the TRPV1 receptor. Additionally, researchers are exploring the possibility of applications in neurological health, cardiovascular effects, and inflammation, although these areas require further investigation.
Safety and Risks
Understanding the safety and risks of Higenamine is essential, given its increasing use in supplements and ongoing research. There’s limited long-term safety data on its effects in humans, and some studies suggest potential impacts on heart rate and blood pressure. It means those with cardiovascular conditions should exercise caution.
Additionally, its effects on neurotransmitters raise concerns about interactions with medications, particularly those for mood or pain. Several sports organizations also ban it due to its potential stimulant-like effects.
Finally, when found in supplements, be aware of quality and purity issues, as contamination is a concern.
Exploring Multifunctional Roles of 4-Hydroxy-3-Methoxybenzylamine HCL in Neuroprotection and Antioxidation
While this is a promising area of research, keep in mind that much of the evidence is still in its early stages.
Neuroprotection
Nerve Cell Survival: Studies suggest that Higenamine might promote the survival and health of neurons (nerve cells), potentially protecting them against damage.
Anti-inflammatory Action: It may have anti-inflammatory effects on the brain and nervous system. Inflammation is implicated in various neurodegenerative diseases.
Neurotransmitter Modulation: Due to its interaction with neurotransmitters like dopamine and serotonin, Higenamine could protect brain function, though the precise mechanisms are still being studied.
Antioxidation
Scavenging Free Radicals: Higenamine appears to be able to scavenge harmful free radicals in the body. Free radicals can damage cells and contribute to various diseases affecting the brain.
Upregulation of Antioxidant Systems: There’s some evidence that Higenamine might increase the body’s natural antioxidant defenses, providing a longer-term protective effect.
How to Store 4-Hydroxy-3-Methoxybenzylamine Hydrochloride?
To maintain the stability and integrity of this compound, it’s essential to store it properly.
- Store between 2°C to 8°C.
- Keep dry in a sealed container.
- Avoid direct light exposure.
- Seal tightly to prevent oxidation.
- Store away from incompatible substances.
- Mark the container with relevant information.
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FAQs
It has shown potential for clinical use in specific treatments, but further research and clinical trials are necessary to determine its efficacy and safety profile in medical applications.
The synthesis of this compound involves various chemical processes, including reactions between appropriate precursors under controlled conditions to achieve the desired compound.
Yes, it is generally considered safe for human consumption when used responsibly and according to recommended dosages.