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Product Name Aconitine
Other Name Wolfsbane, Monkshood, or Devil’s helmet
CAS Number 302-27-2
Molecular Formula C34H47NO11
Molecular Weight 645.73 g/mol
Applications Personal Care, Dietary Supplements, Functional Foods, Animal Nutrition, etc.
Package 1kg,5kg/bag, 25kg/drum


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What Is Aconitine?

Aconitine is a highly potent toxin found in plants of the Aconitum genus, known as wolfsbane, monkshood, or devil’s helmet. This chemical has a long history, appearing in European folklore and used in ancient times as a poison. While plants containing It was once utilized in highly diluted forms within traditional Medicine, Modern Medicine strongly advises against its use due to its extreme toxicity. As a valuable chemical compound supplement ingredient,  Aconitine is Useful in Improving Overall Health when taken in Low Doses.

History of Aconitine

The history of this chemical stretches back to ancient times, when plants containing this toxin were employed as poisons in hunting and warfare across various cultures, including China, Greece, Rome, and by indigenous groups. In medieval Europe, monkshood became infamous for its poisonous properties. A significant milestone occurred in the early 19th century when it was isolated in its pure form. This breakthrough allowed scientists to delve into the precise effects of this potent toxin.

Bulk Aconitine Specification Sheet

Purities of this compound differ depending on the manufacturing process.

Standard-Grade: Highly purified Compound (≥98%) is commonly used as an analytical standard.

  • Calibration:It calibrates instruments used to analyze this compound’s content in plant samples or research solutions.
  • Reference Point:It provides a benchmark for comparing the purity of this chemical extracted or isolated for other research purposes.

Research-Grade: This purity is used in general research can vary more widely.

  • Mid-Range:Around 80-95% of Purities are available and might be suitable for some research applications.
  • High-Grade:Purities closer to the analytical standard (≥98%) can be found and are essential for work where trace contaminants could significantly affect results. 


Standard Grade


White to off-white crystalline powder





Other Ingredient


Test Methods

HPLC, NMR, Melting Point

MOQ (minimum order quantity)



Available (10-20g/bag)

OEM Service

Available, such as capsules, tablets, pills, etc.

ODM Service


Private Label


Contract Manufacturing


 Purpose of Aconitine

It isn’t something intentionally produced. Instead, it exists as a natural defense mechanism within Aconitum plants. Its potent toxicity serves to deter herbivores, ultimately protecting the plant from being consumed.

Applications and Uses

Due to its extreme toxicity, this chemical has limited practical applications. Historically, it has been used in highly diluted forms within traditional Chinese Medicine and some homeopathic practices. However, modern Medicine strongly warns against any use of it because of the significant risks. Its primary application today lies in careful scientific research, where it helps scientists investigate the effects on the nervous system and heart, providing insights into these physiological processes.

Why Is It Being Used for Research Today?

It is primarily used in research today for its pharmacological properties and potential therapeutic applications. Despite its toxicity, researchers are interested in studying the compound and its derivatives for several reasons:

  1. Biomedical Research:It’s impact on ion channels and receptors aids in studying the nervous system and cardiac function, informing therapeutic strategies for pain, arrhythmias, and neurological disorders.
  2. Drug Discovery:This compound and its analogs are lead compounds for new drug development. Structural modifications can produce safer, more effective medications for various conditions.
  3. Pharmacological Screening:This is also used in assays to screen potential drugs’ effects on ion channels and receptors, identifying promising candidates for further development.
  4. Toxicology Studies:Understanding it’s toxicity is crucial for assessing the safety of herbal remedies containing Aconitum species informing regulatory decisions and healthcare practices.

 Is It Safe to Consume?

This compound is not safe to consume. It is a highly poisonous substance, with even minuscule amounts posing a risk of fatality. Symptoms of aconitine poisoning include numbness and tingling sensations in the face and limbs, nausea and vomiting, irregular heartbeats, difficulty breathing, and paralysis. In extreme instances, fatalities may result from heart or respiratory dysfunction.

Exploring Aconitine’s Role in Homeopathic Treatments:  Functions and Benefits

In the realm of  homeopathy, aconitine is believed to be used to treat a range of symptoms, including:

Fear, anxiety, and restlessness: Aconitine is said to alleviate feelings of tension and anxiety.

Acute sudden fever: It is believed to help reduce symptoms of sudden fever.

Weather-related symptoms: It may be helpful for symptoms caused by exposure to dry, cold weather or hot weather.

Piercing pain, coldness, and numbness: These symptoms are purportedly relieved by aconitine.

Influenza or congested colds: It is thought to have some efficacy against flu or colds accompanied by congestion.

Headaches: Particularly heavy, throbbing headaches may find relief with aconitine.

It is important to note that homeopathy is an alternative medicine approach and its theory and practice are different from conventional medicine. In conventional medicine, aconitine is considered to be highly toxic and hence its use in homeopathy should be done with caution and under the guidance of a professional. It is recommended to consult a physician prior to treatment to ensure safety and suitability.

Where to Find a Wholesale Aconitine Powder Supplier?

NutriAvenue stands out as a global leader in supplying supplement ingredients and research compounds, including Aconitine Powder, catering to diverse industries worldwide. NutriAvenue guarantees global accessibility and dependability for clients through its wide-reaching network of partners across the USA, Mexico, Poland, Hungary, France, the UK, and various South American countries, including Brazil, Argentina, Peru, Ecuador, Colombia, Chile, Uruguay, and Paraguay. NutriAvenue is well-known for its dedication to quality, safety, and innovation, providing diverse products supported by thorough testing and adherence to regulatory standards.


While Aconitine has historically been used in traditional Medicine, its extreme toxicity and lack of therapeutic index have led modern Medicine to abandon its use. There are no approved medical applications for Aconitine.

Treatment for Aconitine poisoning is primarily supportive and focused on managing symptoms. It may include respiratory support and cardiac monitoring.

Extreme caution should be exercised when handling this compound or products containing it. Protective equipment such as gloves and masks should be worn, and exposure should be minimized. Proper storage and labeling are also essential to prevent accidental ingestion or contact.

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