Astragalus Polysaccharides

What is Astragalus Polysaccharides?

Astragalus Polysaccharides are derived from the roots of Astragalus membranaceus, a traditional medicinal herb used in China and other Asian countries for centuries. The polysaccharides in Astragalus are a group of bioactive compounds with significant therapeutic potential. These complex carbohydrates are known for their immunomodulatory, antioxidant, and anti-inflammatory properties, making them popular ingredients in dietary supplements, functional foods, and health-related products. Astragalus Polysaccharides are widely used to boost immune function, support respiratory health, and promote general wellness.

Active Ingredients

The primary active ingredients in Astragalus Polysaccharides include several complex sugars and saponins, the most notable being Astragaloside IV. This saponin is the crucial compound associated with many health benefits attributed to Astragalus Polysaccharides, including immune system enhancement and anti-inflammatory effects. In addition to Astragaloside IV, other polysaccharides and flavonoids within the root contribute to its therapeutic potential. These active compounds help regulate the body’s immune response, combat oxidative stress, and improve cell regeneration and repair.

Common Sources

Astragalus Polysaccharides are extracted primarily from Astragalus membranaceus, a perennial plant native to China’s northern and eastern regions. The plant has been cultivated extensively in these areas for its medicinal properties and is also found in parts of Mongolia and Korea. The root of Astragalus is harvested during the autumn, as it contains the highest concentration of bioactive compounds at this time. Once harvested, the root is processed to extract the polysaccharides in supplements, personal care products, and pharmaceuticals.

How Does It Work?

Astragalus Polysaccharides modulate various biological pathways, particularly those related to the immune system and inflammation. The polysaccharides in Astragalus stimulate the production of immune cells, like lymphocytes and macrophages, and promote their activity which are essential for the body’s defense against infections and diseases. They also increase the secretion of cytokines, proteins that regulate immune responses and inflammation.

Astragaloside IV, an essential compound, protects cells from oxidative damage by neutralizing free radicals. This antioxidant activity reduces the dangers of chronic diseases and promotes overall health. Additionally, Astragaloside IV has been found to strengthen the heart health by improving blood circulation and reducing cholesterol levels.

Regarding its adaptogenic properties, Astragalus Polysaccharides help the body resist physical, emotional, and environmental stressors by supporting homeostasis and improving energy metabolism.

Production Process

Harvesting: Mature roots of Astragalus membranaceus are harvested when they reach their peak concentration of active polysaccharides, typically in the autumn season.

Cleaning and Sorting: The roots are thoroughly cleaned to remove soil or impurities. After cleaning, they are sorted based on size and quality to ensure uniformity in the final product.

Drying: The roots are dried naturally under controlled conditions to preserve the bioactive compounds. Alternatively, they can be dried using a low-temperature drying machine to speed up the process while maintaining potency.

Grinding: Once dried, the roots are turned into a fine powder. This powder is sieved to ensure a consistent particle size for the extraction process.

Extraction: The ground powder is soaked in a solvent, such as ethanol or water, to extract the polysaccharides. The solution is filtered to separate plant material, leaving only the liquid extract.

Concentration: To increase the potency of the polysaccharides, excess solvent is removed from the extract using techniques like rotary evaporation or vacuum concentration.

Purification and Standardization: The extract is purified using methods like chromatography to isolate and concentrate the desired active ingredients, such as Astragaloside IV. The concentration of active compounds is standardized to ensure consistency across batches.

Final Processing: The purified extract is mixed with other ingredients (if necessary) to produce the final product, which is then packaged in airtight containers to maintain stability and shelf life.

Quality Control: Each batch undergoes rigorous testing to meet quality and potency standards. Certifications such as Halal and Kosher are obtained as needed for market-specific demands.

Bulk Astragalus Polysaccharides Specifications

Astragalus Polysaccharides: Benefits, Side Effects, And More

Immune System Support: Astragalus Polysaccharides enhance the body’s immune response by promoting the activity of white blood cells and increasing cytokine production. This makes them effective in combating infections and boosting overall immunity.

Anti-inflammatory Effects: Astragalus’s polysaccharides help reduce inflammation in the body, relieving inflammatory conditions such as arthritis and respiratory infections.

Antioxidant Properties: Astragalus Polysaccharides protect cells from oxidative stress, which is a key factor in aging and various chronic diseases by scavenging free radicals.

Cardiovascular Health: Studies suggest that Astragaloside IV helps reduce cholesterol levels and improves blood flow, which can lower the risk of heart disease.

Adaptogenic Effects: Astragalus is an adaptogen that assists the body to cope with stress by balancing cortisol levels and supporting energy production.

Industry Applications and Uses

Dietary Supplements: Astragalus Polysaccharides are commonly used in dietary supplements designed to support immune health, enhance energy levels, and promote overall well-being.

Functional Foods: The extract is often incorporated into functional foods, such as energy bars, herbal teas, and health drinks, to provide additional health benefits, particularly for immune support and stress reduction.

Personal Care Products: Due to its exceptional antioxidant and anti-inflammatory properties, Astragalus Polysaccharides are used in personal care products, including skincare creams, lotions, and anti-aging serums. These products help protect the skin from oxidative damage and reduce inflammation, promoting healthier, more youthful skin.

Animal Nutrition: Astragalus Polysaccharides are also used in animal nutrition to enhance livestock’s immune response and overall health, particularly in promoting growth and improving resistance to infections.

Pharmaceuticals: In traditional Chinese medicine and modern pharmaceuticals, Astragalus Polysaccharides are utilized to treat various ailments, including colds, respiratory infections, and fatigue. Their immunomodulatory effects make them a valuable ingredient in medications designed to boost the body’s natural defenses.

Standard Dosage and Usage

The typical dosage of Astragalus Polysaccharides for dietary supplements ranges from 200 to 500 milligrams on a daily basis, depending on the concentration of active ingredients such as Astragaloside IV. The extract is often taken in divided doses to ensure optimal absorption. It may be taken with or without food. A lower dosage may be sufficient for general immune support, while higher doses may be recommended for managing specific health conditions.

The concentration of astragalus polysaccharides in functional foods or personal care products will vary depending on the intended application and desired benefits. It is important to follow the manufacturer’s guidelines and consult a healthcare professional before using high-concentration extracts, especially for individuals with pre-existing health conditions.

Safety and Side Effects

Astragalus Polysaccharides are generally considered safe when used at recommended doses. However, some individuals may experience mild side effects, such as gastrointestinal discomfort, bloating, nausea, or diarrhea. These symptoms are usually temporary and resolve once the body adjusts to the supplement.

Individuals with autoimmune diseases should use caution when taking Astragalus Polysaccharides, as their immunomodulatory effects could potentially exacerbate symptoms. Additionally, individuals taking immunosuppressive drugs or anticoagulants should consult a healthcare professional before using Astragalus supplements.

Astragalus Polysaccharides VS Reishi Mushroom Polysaccharides

Astragalus Polysaccharides and Reishi Mushroom Polysaccharides are known for their immune-boosting properties, but they differ in their specific mechanisms of action. Astragalus Polysaccharides modulate the immune system by increasing white blood cell activity and cytokine production. At the same time, Reishi Polysaccharides are known for balancing immune function by acting as immunomodulators. Reishi also provides additional benefits for liver health and stress reduction, making it a complementary but distinct option for immune support.

Astragalus Polysaccharides VS Ginseng Extract

Astragalus Polysaccharides and Ginseng Extract are widely used in traditional medicine for their adaptogenic properties. While Astragalus primarily supports immune health and reduces inflammation, Ginseng is known for its ability to boost physical performance, reduce fatigue, and improve cognitive function. Both extracts offer complementary benefits, but Ginseng is more commonly associated with energy and mental clarity, whereas Astragalus focuses on immune support and stress resistance.

How Should This Ingredient Be Stored?

Astragalus Polysaccharides must be stowed away in a cool, dry place that is away from direct source of heat and sunlight. The extract is sensitive to moisture and air, so be sure to kee it in an airtight container to prevent degradation. Refrigeration is recommended for long-term storage to preserve its potency and extend its shelf life. Always follow the storage instructions provided by the manufacturer to ensure the product remains effective.

Where Can I Find Wholesale Astragalus Polysaccharides Supplier?

For high-quality, wholesale Astragalus Polysaccharides, Nutri Avenue is a trusted global supplier. The company sources its Astragalus from premium natural sources and ensures stringent quality control through comprehensive testing. Nutri Avenue offers competitive pricing, reliable supply chains, and customization options, including OEM and ODM services. They cater to businesses in the dietary supplement, personal care, and pharmaceutical industries. For more information or to place an order, visit Nutri Avenue’s website.