Cyanidin-3-Glucoside

What Is Cyanidin-3-Glucosides (C3G)?

Cyanidin-3-glucoside is also known as Cyanidine 3-glucoside, Cyanidin 3-O-glucoside, Cyanidin-3-O-beta-D-glucoside, Cyanidin 3-monoglucoside and so on. monoglucoside, etc.

It is one of the anthocyanosides. It is mainly found in black rice, black beans, purple potatoes, and other plants. Chrysin is an anthocyanin. It is the 3-glucoside of kuromanin.

Sourced From

It is commonly found in berries, grapes, cherries, and purple corn.

Cyanidin-3-Glucoside offered by Nutri Avenue is extracted from Black Rice.

Is It Naturally Occurring or Is It Artificially Synthesized?

It is a natural compound found in plants, and plants can synthesize it through their metabolic processes.

Specification Sheet

Cyanidin-3-Glucosides Benefits

1. Antioxidant and anti-inflammatory

C3G, as an anthocyanin, has powerful antioxidant properties that neutralize free radicals, reduce oxidative stress, and have anti-inflammatory effects.

2. Improves memory and cognitive function

Research suggests that consuming foods rich in C3G may help improve spatial memory and cognitive function.

3. Regulation of energy metabolism

It is believed to affect energy metabolism and insulin sensitivity. It may help regulate systemic energy balance and combat obesity.

4. Promoting the formation and function of brown adipose tissue (BAT)

C3G can increase energy expenditure, limit weight gain, maintain glucose homeostasis, improve cold tolerance, and enhance BAT activity 31.

5. Cellular uptake and transport mechanisms

Its intracellular uptake and transport, as well as the mechanism of its anti-inflammatory effects, have been studied.

6. Neuroprotective effects

In the central nervous system, anthocyanin analogs have been reported to have the potential for the prevention and/or treatment of neurodegenerative diseases.

7. Anti-tumor activity

It shows significant anti-tumor activity and may inhibit tumor cell proliferation through several mechanisms.

8. Improvement of insulin sensitivity and glucose tolerance

The compound is capable of improving insulin sensitivity and glucose tolerance. It has potential benefits for metabolic diseases such as obesity and diabetes.

What Is The Bioavailability Of Cyanidin 3-O-glucoside?

The compound’s structure contains phenolic hydroxyl groups, making it less stable and prone to decomposition under environmental conditions. It limits its use in food and pharmaceutical applications.

How to Improve it?

Below are the various ways researchers have improved the bioavailability of Cyanidin 3- glucoside. Thereby enhancing its potential for application in food additives and drug delivery systems.

1. Nano-encapsulation technology

Encapsulation of C3G in nanocarriers using nanotechnology can improve its stability and bioaccessibility. Examples include liposome technology, guar gum-coated nanotrophs, and carboxymethyl chitosan encapsulated nanotrophs. These technologies can protect C3G from environmental factors and facilitate its absorption in the body.

2. Liposomes and nanoparticles

The solubility and stability of Cyanidin-3-Glucosides in food systems can be improved by customizing them into liposomes or nanoparticles.

3. Polysaccharide- and protein-based carriers

Polysaccharides and proteins are utilized as carrier materials and prepared into nanocapsules or microcapsules by physical or chemical methods.

4. Nano/microgels

Nano or micron-level gel systems encapsulate C3G to improve its stability and release efficiency during digestion.

5. Gut microbiota regulation

The metabolism of C3G in the gut can produce biologically active phenolic metabolites, and the bioavailability and health benefits of C3G can be improved by modulating the composition and function of the gut microbiota50.

        6. Chemical modification

Chemical modification of C3G molecules, such as glycosylation, esterification, etc., to improve their solubility and stability.

7. Food formulation design

Rational matching of C3G with other ingredients, such as lipids and proteins, in food formulations, can improve the solubility and bioaccessibility of C3G.

Applications and Uses

1. Nutritional Supplements: Due to its health benefits, it is integrated as an ingredient in dietary supplements, targeting to improve heart health, blood sugar regulation, and eye health.
2. Food and Beverage Industry:It is typically added to foods and beverages such as smoothies, energy bars, and other drinks to improve their nutritional profile.
3. Sports Nutrition:It is added to sports supplements to improve exercise performance and endurance and reduce fatigue.
4. Cosmetics and Skincare:Due to its antioxidant properties, it is incorporated into skincare products to help against oxidative damage caused by UV radiation.
5. Food Coloring:C3G is a natural pigment responsible for the color of fruits and vegetables, making it a good coloring agent while increasing its nutritional profile.

Does It Have Side Effects?

Mild side effects, such as allergic reactions, may occur, and it may react with medications varying between individuals.

Is It Safe to Consume?

It is generally safe when consumed under the recommended dosage and in a diet.

Where To Buy Cyanidin-3-Glucoside?

Looking for a reliable supplier that offers premium quality products at competitive wholesale prices? Don’t worry, Nutri Avenue is here! We offer C3G and other supplement ingredients that are meticulously sourced and tested.

For orders and information, contact us at info@nutriavenue.com or 423-393-7690