Dicalcium Phosphate Dihydrate

What Is Dicalcium Phosphate Dihydrate?

Dicalcium phosphate dihydrate is a white, odorless powder derived from calcium phosphate. It is widely used in diverse industries due to its excellent bioavailability and versatile properties. Dicalcium Phosphate Dihydrate is a source of calcium and phosphorus, making it a valuable ingredient in dietary supplements, functional foods, and animal nutrition products. It also plays a significant role in personal care products due to its gentle abrasive and stabilizing properties.

Sources from

Dicalcium phosphate dihydrate powder is typically sourced from naturally occurring mineral deposits or synthesized through chemical processes. The majn raw materials for its production are phosphoric acid and calcium carbonate. These compounds react to form Dicalcium Phosphate Dihydrate, which is then purified and processed into a fine powder.

Specifications sheet reference

Dicalcium Phosphate Dihydrate VS Anhydrous

Dicalcium phosphate (DCP) is a commonly used chemical in various industries, particularly in animal feed, pharmaceuticals, and food additives. It exists in two primary forms: dihydrate (DCPD) and anhydrous (DCPA). Here’s a comparison between the two.

Dicalcium Phosphate Dihydrate (DCPD)

Chemical Formula: CaHPO4·2H2O

Molecular Weight: 172.09 g/mol

Water Content: Contains two water molecules (dihydrate).

Appearance: Typically appears as a white, crystalline powder.

Solubility: More water-soluble than its anhydrous counterpart.

Applications:

• Animal Feed: Commonly used as a dietary supplement for livestock to provide calcium and phosphorus.
• Food Additive: Utilized as a leavening agent in the baking industry.
• Pharmaceuticals: Used as a tableting agent and a source of calcium and phosphorus in dietary supplements.

Stability: Less stable under high-temperature conditions than anhydrous form.

Dicalcium Phosphate Anhydrous (DCPA)

Chemical Formula: CaHPO4

Molecular Weight: 136.06 g/mol

Water Content: Contains no water molecules (anhydrous).

Appearance: Typically appears as a white, crystalline powder.

Solubility: Less soluble in water than in dihydrate form.

Applications:

• Pharmaceuticals: Widely used as an excipient in tablet formulations due to its good compressibility.
• Food Industry: Functions as a calcium and phosphorus supplement and in some leavening agents.

Stability: The dihydrate form is more stable under high-temperature and humid conditions.

Key Differences Between Dicalcium Phosphate Dihydrate VS Anhydrous

1. Water Content: The dihydrate form contains water molecules, while the anhydrous form does not.
2. Solubility: DCPD is more water soluble than DCPA.
3. Stability: DCPA is more stable under high temperature and humidity than DCPD.
4. Applications: Both forms are used in the pharmaceutical, food, and feed industries, but their specific uses may vary depending on their properties, such as solubility and stability.

Selection Criteria

Solubility Needs: Choose DCPD if higher solubility is required.

Stability Requirements: Opt for DCPA for applications requiring stability under heat and moisture.

Application-Specific Needs: Consider the application’s specific requirements, such as the need for an excipient in pharmaceuticals or a nutrient supplement in animal feed.

Both forms of dicalcium phosphate are valuable in their respective applications, and the choice between dihydrate and anhydrous depends on the specific requirements of the end-user.

Dicalcium Phosphate Dihydrate VS Hydroxyapatite

These two ingredients are both calcium phosphate compounds widely used in various fields such as medicine, dentistry, and materials science. Here is a detailed introduction to Hydroxyapatite.

Chemical Formula: Ca10(PO4)6(OH)2

Molecular Weight: 502.31 g/mol

Water Content: Does not contain water molecules but has hydroxyl groups.

Appearance: Typically appears as a white to off-white powder.

Solubility: Poorly soluble in water.

Applications:

• Biomedical Applications: Widely used in bone grafts, dental implants, and tissue engineering due to its similarity to natural bone mineral.
• Orthopedics and Dentistry: Utilized for coating metal implants to improve biocompatibility and promote bone growth.
• Drug Delivery: Used as a carrier for controlled drug release due to its biocompatibility and ability to bond with bone tissue.
• Cosmetics: Incorporated in some skincare products for their mild abrasiveness and remineralizing properties.

Stability: Highly stable, especially under physiological conditions, making it suitable for long-term implants in the body.

Key Differences Between Dicalcium Phosphate Dihydrate VS Hydroxyapatite

Chemical Composition: DCPD contains water molecules, while HA contains hydroxyl groups.

Solubility: DCPD is more soluble in water than HA, which is poorly soluble.

Applications:

DCPD: More commonly used in animal feed, food additives, and pharmaceutical formulations.

HA: Predominantly used in biomedical applications, particularly for bone and dental repair and regeneration.

Biocompatibility: HA is highly biocompatible and osteoconductive, making it ideal for medical implants and bone grafts, whereas DCPD is less commonly used for such applications.

Stability: HA is more stable under physiological conditions and suitable for long-term medical use, while DCPD is less stable under high temperatures.

Selection Criteria

1. Biomedical Applications: HA is preferred for its superior biocompatibility, osteoconductivity, and stability, making it suitable for implants and bone grafts.
2. Nutritional Supplements: DCPD is chosen for its solubility and ease of incorporation into dietary supplements for livestock and humans.
3. Industrial Use: The specific properties required for the application, such as solubility and stability, will dictate the choice between DCPD and HA.

In summary, while dicalcium phosphate dihydrate and hydroxyapatite are valuable calcium phosphate compounds, their applications differ significantly due to their distinct chemical properties and stability profiles.

2 More Comparisons: Dicalcium Phosphate Dihydrate VS 

• Tricalcium Phosphate

These two are calcium phosphate compounds used in supplements and food fortification. However, they differ in their calcium and phosphorus content.

Dicalcium Phosphate Dihydrate contains a higher proportion of phosphorus, making it more suitable for applications requiring a balanced source of both minerals. On the other hand, Tricalcium Phosphate has a higher calcium content and is often used when additional calcium is needed without a corresponding increase in phosphorus.

• Calcium Carbonate

While both are used as calcium supplements, they have different properties and applications. Dicalcium Phosphate Dihydrate provides calcium and phosphorus, making it suitable for mineral supplementation. Calcium Carbonate, which has a higher calcium content, is primarily used for calcium supplementation and antacid formulations. Calcium Carbonate may cause gastrointestinal discomfort in some individuals, while Dicalcium Phosphate Dihydrate is generally better tolerated.

Factories: How To Produce Bulk Dicalcium Phosphate Dihydrate Powder?

1. Raw Material Selection: High-quality phosphoric acid and calcium carbonate are chosen to produce.
2. Reaction: The phosphoric acid and calcium carbonate react under controlled conditions to form this compound.
3. Filtration: The mixture is filtered to remove impurities and isolate the ingredient.
4. Washing: The filtered product is washed to ensure purity and remove residual reactants.
5. Drying: The washed Dicalcium Phosphate Dihydrate is dried to achieve the desired moisture content.
6. Grinding: The dried product is ground into a fine powder to ensure uniform particle size and consistency.
7. Quality Control: Comprehensive tests ensure the product meets industry standards for purity, composition, and particle size.
8. Packaging: The final product is packed in appropriate containers to maintain stability and prevent contamination.

How Does It Work?

Dicalcium Phosphate Dihydrate works primarily as a source of calcium and phosphorus, two essential minerals for the human body. Calcium is crucial for more robust bones and teeth, muscle contraction, and blood clotting. Phosphorus, on the other hand, is vital in energy production, bone mineralization, and the formation of DNA and RNA. The bioavailability of these minerals from this compound makes it an effective ingredient in supplements and functional foods.

Dicalcium Phosphate Dihydrate: Benefits, Uses, And More

• Bone Health: It provides a readily absorbable form of calcium and phosphorus, essential for bone density and strength.
• Dental Health: It is used in dental care products to promote strong teeth and prevent cavities.
• Muscle Function: Calcium from this ingredient supports muscle contraction and relaxation.
• Metabolic Functions: Phosphorus is involved in energy production and metabolic processes.
• Nerve Function: Calcium is crucial in neurotransmitter release and nerve signal transmission.

Applications And Uses

First, Dicalcium Phosphate Dihydrate is a popular ingredient in dietary supplements due to its high bioavailability and mineral content. It is used to fortify products with calcium and phosphorus, supporting bone health, muscle function, and overall well-being. It is available in various forms, including tablets, capsules, and powders.

Then, in functional foods, it is used to enhance the nutritional profile of products. It is commonly added to cereals, beverages, and snack bars to provide an additional source of calcium and phosphorus.

In personal care products, Dicalcium Phosphate Dihydrate is a gentle abrasive in toothpaste, providing cleaning action without damaging tooth enamel. It also acts as a stabilizer in creams and lotions, ensuring product consistency and shelf stability.

Standard Dosage and Usage

The standard dosage of Dicalcium Phosphate Dihydrate for dietary supplements varies depending on the intended use and formulation. Typically, a daily dose of 200-600 milligrams is recommended, providing approximately 90-270 milligrams of elemental calcium and 70-210 milligrams of elemental phosphorus. It is usually divided into two or three doses and is often taken with meals to enhance absorption.

Is It Safe?

Dicalcium Phosphate Dihydrate is generally considered safe when used as directed. However, excessive calcium intake may lead to hypercalcemia, a condition characterized by an increased calcium level in the blood. This condition can cause nausea, vomiting, constipation, and kidney stones. Phosphorus is also safe in recommended amounts, but excessive intake can lead to calcium and phosphorus levels imbalances. Adhering to recommended dosages and consult a healthcare professional is critical before starting any new supplement regimen.

How Should It Be Stored?

Dicalcium Phosphate Dihydrate must be safely kept in a cool, dry place. It must also be stowed away from direct sunlight and moisture. It must be kept in an airtight container to prevent contamination and degradation. The storage area should be free from strong odors and chemicals that might affect the product’s quality. For long-term storage, refrigeration is recommended to maintain its stability and potency. Always follow the manufacturer’s storage instructions to ensure the product remains effective and has a long shelf life.

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