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Diosmin Powder

Product Name Diosmin Powder
Other Names Diosmetin-7-O-rutinoside, Venosmin, Daflon, Diosmina, Diovenor, Diosvein, Flavonoid 450, Vasculera
CAS Number 520-27-4
Molecular Formula C28H32O15
Molecular Weight 608.54 g/mol
Applications Personal Care, Dietary Supplements, Functional Foods, Animal Nutrition, etc.
Package 1kg, 5kg/bag, 25kg/drum


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What Is Diosmin?

Diosmin is a naturally occurring flavonoid compound that belongs to a larger group of plant pigments known as citrus bioflavonoids. It is primarily derived from citrus fruits, particularly the bitter orange (Citrus aurantium) and certain species of the Rutaceae family. It is often used as an ingredient in dietary supplements and medications.

Common Bulk Pure Diosmin Powder Specifications

  • Diosmin 90% pure powder
  • Diosmin 95% pure powder
  • Diosmin 98% pure powder
AppearanceFine powder
Content≥ 90%
Purity≥ 95%
Particle Size80 mesh or as per customer requirement
CertificationsGMP, ISO 9001, ISO 22000
Other IngredientNone
SolventEthanol or water
Water Content≤ 5%
Test MethodHPLC, UV-VIS
MOQ (minimum order quantity)1kg
SampleAvailable (10-20g/bag)
OEM ServiceAvailable, such as capsules, tablets, pills, etc.
ODM ServiceAvailable
Private LabelAvailable
Contract ManufacturingAvailable

Where Does Diosmin Extract From?

Diosmin is primarily extracted from the peel of citrus fruits, particularly the bitter orange (Citrus aurantium) and certain species of the Rutaceae family.

What Is Diosmin Powder Manufacturing Process?

The citrus peels are typically dried and subjected to various extraction methods to extract diosmin. Solvent extraction, such as using ethanol or a mixture of water and ethanol, is commonly employed to obtain diosmin from the dried citrus peels. The extraction process helps separate diosmin from other components of the citrus peel, resulting in a concentrated form of the compound.

After extraction, the diosmin extract may undergo further purification to remove impurities and obtain a higher purity level. These purification processes can involve techniques such as chromatography or crystallization.

Once the diosmin has been extracted and purified, it can be processed into various forms, such as dietary supplements or medications. It can promote venous health and manage conditions related to venous insufficiency.

Diosmin Powder Manufacturing Process

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What is Diosmin used for?

Diosmin is used for various purposes, particularly in vascular health areas.

Diosmin is recognized for its potential therapeutic effects on the circulatory system, precisely its venotonic and vasoprotective properties. It is commonly used to manage various vascular conditions, particularly those related to venous insufficiency, such as chronic venous disorders and hemorrhoids.

When ingested, diosmin is believed to improve venous tone and function by increasing the venous return and reducing the permeability of the blood vessels. These actions help alleviate symptoms associated with venous insufficiency, such as leg pain, swelling, heaviness, and the appearance of varicose veins.

Additionally, diosmin is thought to have anti-inflammatory effects and antioxidant activity. It may help reduce inflammation, oxidative stress, and the release of inflammatory mediators, contributing to its potential benefits for various conditions, including chronic venous disorders and other inflammatory conditions.

What ingredients can use with Diosmin?

Who is the top bulk Diosmin supplier?

Nutri Avenue offers common flavonoids, including Diosmin. We ship by air, ship, and couriers. Five U.S. warehouses support our customers in getting raw ingredients more quickly.


Yes, Diosmin is the main ingredient in the medication Daflon, a brand name product containing Diosmin and another flavonoid called hesperidin. They are used for similar purposes in managing venous disorders.

Yes, Diosmin is generally considered safe when used as a dietary supplement ingredient.

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