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Magnesium Orotate Powder

Product Name Magnesium Orotate Powder
Other Names Magnesium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate, Magnesium orotate dihydrate, Magnesium diorotate, Magnesium salt of orotic acid,  Magnesium 2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-olate, Orotic acid magnesium salt, Magnesium 2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl carboxylate, Magnesium 2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-carboxylate, Magnesium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate, Magnesium orotate trihydrate.
CAS Number 34717-03-8
Molecular Formula C10H6MgN4O8
Molecular Weight 334.48 g/mol
Applications Personal Care, Dietary Supplements, Functional Foods, Animal Nutrition, etc.
Package 1kg,5kg/bag, 25kg/drum


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Magnesium Orotate Powder


What Is Magnesium Orotate?

Magnesium orotate is a compound made up of magnesium and orotic acid. Orotic acid is a substance found naturally in the body and in certain foods. When magnesium combines with orotic acid, it forms a salt called magnesium rotate.

Magnesium orotate is valued for its potential health benefits and ability to help the body absorb more magnesium. Magnesium is an essential mineral in many vital body processes, such as producing energy, supporting muscle function, transmitting nerve signals, and maintaining healthy bones and teeth.

Combining magnesium and orotic acid has specific advantages. Orotic acid is believed to help magnesium enter cells more efficiently, which may improve how well the body absorbs and uses it. This increased absorption makes magnesium orotate a beneficial supplement, especially for people who have trouble absorbing or using other types of magnesium.

What is Magnesium Orotate Dihydrate?

Magnesium orotate dihydrate is a type of magnesium orotate containing water molecules. Specifically, it has two water molecules for every magnesium orotate molecule, making it a hydrated form.

To create magnesium orotate dihydrate powder, magnesium and orotate ions are combined, and water molecules become part of the compound’s structure. These water molecules are chemically attached to the magnesium orotate.

Water content in magnesium orotate dihydrate powder can affect how it behaves physically and chemically compared to forms without water. It may have different properties regarding how easily it dissolves in liquids and its stability over time.

Magnesium orotate dihydrate is commonly found in dietary supplements and medicines as a source of magnesium. The combination of magnesium and orotate is thought to provide potential health benefits, and the dihydrate form has its specific composition due to the presence of water molecules.

Common Bulk Pure Magnesium Orotate Specifications

The following Magnesium Orotate powder specification is common in the market. You can regard it as a reference.

  • 10% Magnesium Orotate powder
AppearanceWhite crystalline powder
ContentMin. 95% Magnesium Orotate
PurityMin. 99%
CertificationsGMP, ISO 9001
Other IngredientNone
Test MethodHPLC, FTIR, XRD, Moisture Analysis
MOQ (minimum order quantity)1 kg
SampleAvailable (10-20g/bag)
OEM ServiceAvailable, such as capsules, tablets, pills, etc.
ODM ServiceAvailable
Private LabelAvailable
Contract ManufacturingAvailable

What Is The Source Of Magnesium Orotate Powder?

Magnesium orotate powder is made in a laboratory by combining magnesium and orotate ions. Orotate is a substance that occurs naturally in small amounts in the body and in certain foods. However, the specific magnesium orotate powder used as a supplement or ingredient is usually produced through chemical processes in a lab.

The magnesium ions used to create magnesium orotate can come from different sources, such as magnesium chloride, magnesium carbonate, or magnesium oxide. These magnesium salts react with orotate ions derived from orotic acid, forming magnesium orotate.

Synthetic production of magnesium orotate allows for precise control over the quality and composition of the final product. This ensures that the magnesium orotate powder is consistent and meets standardized requirements for dietary supplements and pharmaceutical formulations.

Although the raw materials for magnesium orotate powder come from natural sources, the manufacturing process takes place in a laboratory using chemical synthesis. This is necessary to produce a pure and reliable magnesium orotate suitable for commercial use.

What Is Magnesium Orotate Powder Manufacturing Process?

The manufacturing process of magnesium orotate powder involves several key steps to produce the final product.

  1. Sourcing of Raw Materials: The process begins by obtaining the necessary raw materials, which typically include magnesium salts (e.g., magnesium chloride, magnesium carbonate, or magnesium oxide) and orotic acid.
  2. Mixing and Reaction: The magnesium salts and orotic acid are carefully measured and mixed in specific ratios. This mixture is then subjected to a reaction, often in the presence of solvents or catalysts, to facilitate the formation of magnesium orotate.
  3. Precipitation and Filtration: The reaction mixture is usually treated to encourage the precipitation of magnesium orotate crystals. Filtration is then performed to separate the solid crystals from the liquid components.
  4. Washing and Drying: The filtered magnesium orotate crystals undergo washing to remove impurities and residual solvents. Afterward, the crystals are dried to eliminate any remaining moisture and achieve the desired powder form.
  5. Grinding and Sieving: The dried magnesium orotate crystals may be further processed through grinding or milling to reduce the particle size and obtain a fine powder. Sieving or screening can be performed to ensure uniformity and remove any larger particles.
  6. Quality Control and Testing: Throughout the manufacturing process, various quality control measures and testing are conducted to assess the purity, composition, and physical characteristics of the magnesium orotate powder. This may include techniques like HPLC (High-Performance Liquid Chromatography) for content analysis and FTIR (Fourier Transform Infrared Spectroscopy) for identification.
  7. Packaging and Storage: Once the magnesium orotate powder has passed quality control checks, it is typically packaged in appropriate containers, such as sealed bags or bottles, to protect it from moisture and ensure stability. Proper labeling and storage conditions are implemented to maintain the quality and shelf life of the product.

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What are Magnesium Orotate benefits?

Magnesium orotate offers several potential benefits due to its combination of Magnesium and orotate. Here are some commonly mentioned benefits:

  • Improved Magnesium Absorption: Magnesium orotate is thought to enhance the absorption and utilization of Magnesium in the body compared to other forms of magnesium supplements. This can help ensure sufficient levels of Magnesium for various bodily functions.
  • Cardiovascular Health: Magnesium is vital in maintaining a healthy cardiovascular system. Magnesium orotate is often suggested to support heart health by promoting normal heart rhythm, maintaining healthy blood pressure levels, and supporting overall cardiovascular function.
  • Energy Production and Muscle Function: Magnesium is vital in producing energy within cells and supporting healthy muscle function. Magnesium orotate may help support energy metabolism and maintain healthy muscle function.
  • Bone Health: Magnesium is essential in maintaining healthy bones. It works alongside calcium to support bone density and mineralization. Magnesium orotate may contribute to overall bone health and help support bone strength.
  • Nervous System Support: Magnesium is involved in nerve transmission and supports the proper functioning of the nervous system. Magnesium orotate may aid in maintaining a healthy nervous system and support nerve function.
  • Overall Well-being: Adequate magnesium levels are crucial for general well-being. Magnesium orotate is believed to help maintain optimal magnesium levels in the body, which can positively impact mood, stress management, and overall health.

Who is the top pure bulk Magnesium Orotate Supplier?

Nutri Avenue is a top supplier of pure bulk Magnesium Orotate. We are known for our high-quality supplement ingredients and have earned a strong reputation in the industry. As an FDA-accredited company, we prioritize strict quality standards to guarantee the purity and safety of our raw ingredients. Our customer-focused approach makes us unique, including our five conveniently located warehouses across the USA. Customers can easily access our premium Magnesium Orotate and other supplement ingredients. When you choose Nutri Avenue, you can trust that you are sourcing your bulk Magnesium Orotate from a reliable and reputable supplier.

What types of Magnesium are offered by Nutri Avenue?

Magnesium Orotate: Magnesium orotate powder is a compound where Magnesium is combined with orotic acid. It is known for its potential health benefits and ability to help the body absorb Magnesium more effectively.

Magnesium Citrate: Magnesium citrate powder combines Magnesium and citric acid. The body quickly absorbs it, commonly used to support digestive health. It also has Anhydrous Magnesium Citrate powder to choose from.

Magnesium Taurate: Magnesium taurate powder is a form of Magnesium combined with taurine, a compound similar to amino acids. It is believed to affect cardiovascular health and support a healthy heart positively.

Magnesium L-Threonate: Magnesium L-Threonate powder is a form of Magnesium often praised for its potential cognitive benefits. It can cross the blood-brain barrier, improving brain health and cognitive function.

Magnesium Glycinate: Magnesium glycinate powder is a form of Magnesium bonded to glycine, an amino acid. It is highly bioavailable and is a preferred choice for individuals seeking magnesium supplementation without experiencing gastrointestinal side effects.

Magnesium Stearate: Magnesium stearate powder is a magnesium salt of stearic acid. It is commonly used to produce supplements and medications as a flow agent or lubricant to prevent ingredients from clumping together.

Magnesium Ascorbyl Phosphate Powder: Magnesium ascorbyl phosphate is a magnesium salt of ascorbic acid, a vitamin C form. It is often used in skincare products for its potential antioxidant properties and ability to brighten the skin.

L-Threonic Acid Magnesium Salt Powder: L-Threonic Acid Magnesium Salt is a compound where Magnesium is combined with L-threonic acid. It is sometimes used in dietary supplements and is believed to have potential benefits for overall health.

Magnesium Oxide Powder: Magnesium oxide is a common form of magnesium supplement. It has a high concentration of Magnesium but is less easily absorbed by the body than other forms. It is often used to support magnesium levels in the body.

Magnesium Gluconate Dihydrate Powder: Magnesium gluconate dihydrate is a compound where Magnesium is bound to gluconic acid. It is often a dietary supplement to support magnesium intake and well-being.

For more types of Magnesium powder you want to order, please get in touch with Nutri Avenue to support you at wholesale price.


Magnesium Orotate is generally safe to use in supplements as directed. It’s a type of Magnesium that most people can tolerate well. However, like any dietary supplement, following the recommended dosage and talking to a healthcare professional before starting a new supplement routine is essential. Some people might be more sensitive to magnesium orotate or have certain medical conditions that require caution or adjusting the dosage. Taking high amounts of Magnesium, regardless of the source, can cause a laxative effect. So as long as it’s used responsibly and according to the guidelines, Magnesium Orotate is a safe choice for maintaining magnesium levels in the body.

Magnesium orotate is easily absorbed and used by the body. The orotic acid in magnesium orotate helps Magnesium enter cells more effectively, improving its absorption and utilization. This makes magnesium orotate a beneficial choice for individuals who may struggle with absorbing or using other forms of Magnesium.

Magnesium Orotate Powder is considered to have good bioavailability because it combines Magnesium with orotic acid. Orotic acid helps Magnesium enter cells more quickly, which can improve how well it is absorbed and used by the body. This means that Magnesium Orotate Powder could be a practical choice for people who want to maintain or raise their magnesium levels.


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