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Naringenin Powder

Product Name Naringenin Powder
Other Names (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one, (S)-Naringenin, Naringenol, Naringinol, 4′,5,7-Trihydroxyflavanone, 5,7,4′-Trihydroxyflavanone, NAR, 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (S)-NSC 407291
CAS Number 480-41-1
Molecular Formula C15H12O5
Molecular Weight 272.25 g/mol
Applications Personal Care, Dietary Supplements, Functional Foods, Animal Nutrition, etc.
Package 1kg,5kg/bag, 25kg/drum


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What Is Naringenin?

Naringenin is a flavonoid compound found in various citrus fruits, particularly grapefruits. It belongs to a class of plant compounds known as flavonoids for their antioxidant and anti-inflammatory properties. Naringenin is responsible for the bitter taste of grapefruits and has gained attention for its potential health benefits.

Research suggests that Naringenin may have various biological activities, including antioxidant, anti-inflammatory, anti-cancer, and anti-diabetic effects. It has been studied for its potential to inhibit certain enzymes involved in the metabolism of drugs, which can affect their absorption and bioavailability in the body.

Naringenin has also been investigated for its potential to modulate lipid metabolism and reduce cholesterol levels, making it a subject of interest in cardiovascular health research. Additionally, it has shown promise in neuroprotective studies, with potential applications in preventing and treating neurodegenerative diseases.

While Naringenin is naturally present in citrus fruits, it is also available in supplement form. It is important to note that further research is needed to fully understand the therapeutic benefits and potential risks associated with naringenin supplementation.

Common Bulk Pure Naringenin Powder Specifications

The possible purities of standard bulk pure Naringenin powder can include the following.

  1. Naringenin Pure 98% Powder (Grapefruit extract)
  2. Naringenin 99% Pure Powder
  3. Pure Powdered Naringenin ≥99% by HPLC
AppearanceOff-white to light yellow powder
Content≥98% Naringenin
Purity≥99% by HPLC
Particle SizeCustomizable, fine powder
CertificationsISO 9001, GMP, Halal, Kosher
Other IngredientNone
Water Content≤5%
Test   MethodHPLC, FTIR, Microbiological
MOQ (minimum order quantity)1kg
SampleAvailable (10-20g/bag)
OEM ServiceAvailable, such as capsules, tablets, pills, etc.
ODM ServiceAvailable
Private LabelAvailable
Contract ManufacturingAvailable

What Does Naringenin Powder Make From?

Naringenin is a naturally occurring compound found in various citrus fruits, with grapefruits being one of the primary sources. The citrus plant synthesizes it through its metabolic pathways. Specifically, Naringenin is derived from a precursor compound called naringenin chalcone.

When the plant undergoes specific enzymatic reactions, such as the action of chalcone synthase, naringenin chalcone is formed. Subsequently, through chalcone isomerase, naringenin chalcone is converted into Naringenin.

It’s important to note that Naringenin is not exclusively found in grapefruits. It is also present in other citrus fruits, such as oranges, lemons, and limes, albeit in varying concentrations. Additionally, Naringenin can be obtained from grapefruit extract or through extraction methods from citrus fruit peels or other botanical sources.

Naringenin is a natural compound synthesized by citrus plants and can be obtained from various citrus fruits and their extracts.

What Is The Best Source Of Naringenin Powder?

The most commonly used source of Naringenin powder is grapefruit extract. Grapefruits are a rich source of Naringenin and are often used as the primary raw material for extracting Naringenin. The peel and seeds of grapefruits contain relatively higher concentrations of Naringenin than flesh or juice.

The extraction process involves isolating Naringenin from the grapefruit peel or other parts of the fruit. After extraction, the Naringenin is typically further processed and purified to obtain a concentrated powder form, which can be used in various applications and formulations.

While grapefruit extract is the most commonly used source of Naringenin powder, it’s worth mentioning that Naringenin can also be derived from other citrus fruits, such as oranges, lemons, and limes, although the concentrations may vary. Additionally, Naringenin can be synthesized in laboratories through chemical processes, but natural sources like grapefruit extract are preferred for obtaining Naringenin due to their higher compound content.

What Is Naringenin Powder Manufacturing Process?

The manufacturing process of Naringenin powder typically involves the following steps:

  1. Sourcing and Preparation: The initial step involves sourcing the raw materials, often grapefruits or other citrus fruits known to contain Naringenin. The fruits are carefully selected, ensuring they are ripe and of good quality. The peels are separated from the fruit pulp.
  2. Extraction: Naringenin is extracted from the citrus fruit peels using various methods, such as solvent extraction or steam distillation. Solvents like ethanol or water may be used to extract Naringenin from the peels. The extraction process aims to separate Naringenin from other compounds present in the peels.
  3. Purification: After extraction, the crude Naringenin extract undergoes purification to remove impurities and isolate the Naringenin compound. Techniques like filtration, solvent evaporation, and chromatography may be employed to achieve a higher purity level.
  4. Drying: The purified Naringenin solution or concentrate is then subjected to drying methods to remove excess moisture and obtain a dry powder form. Standard drying techniques include spray drying, freeze drying, or vacuum drying.
  5. Particle Size Reduction: Depending on the desired specifications, the Naringenin powder may undergo further processing to achieve the desired particle size. This step involves milling or grinding the dried powder to reduce particle size and improve its dispersibility.
  6. Quality Control and Testing: Throughout the manufacturing process, quality control measures are implemented to ensure the purity, potency, and safety of the Naringenin powder. High-performance liquid chromatography (HPLC) or spectroscopy is utilized to verify the concentration of Naringenin and detect potential impurities.
  7. Packaging: The final Naringenin powder is typically packed in suitable containers, such as airtight pouches or sealed jars, to protect it from moisture, light, and oxidation. Proper packaging helps maintain the quality and stability of the Naringenin powder during storage and transportation.
Naringenin powder manufacturing process

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What is Naringenin good for?

Naringenin has been studied for its potential health benefits and is believed to possess several beneficial properties. Here are some of the areas where Naringenin shows promise.

  1. Antioxidant Activity: Naringenin demonstrates antioxidative properties, thereby offering cellular protection against oxidative stress and the detrimental effects induced by free radicals.
  2. Anti-inflammatory Effects: Naringenin has anti-inflammatory properties and may help reduce inflammation. Chronic inflammation is associated with various diseases, so reducing inflammation can positively affect overall health.
  3. Cardiovascular Health: Naringenin has been studied for its potential cardiovascular benefits. It may help reduce cholesterol levels, improve blood lipid profiles, and enhance blood flow, promoting heart health.
  4. Anti-Cancer Potential: Some research suggests that Naringenin may have anti-cancer properties, including inhibiting the growth of cancer cells and promoting apoptosis (programmed cell death) in certain types of cancer cells. However, more studies are needed to understand its effectiveness in cancer prevention and treatment fully.
  5. Metabolic Health: Naringenin may have beneficial effects on metabolic health. It has been investigated for its potential to regulate blood sugar levels, improve insulin sensitivity, and support weight management.
  6. Neuroprotective Effects: Naringenin has shown promise in protecting neurons and supporting brain health. It may help prevent or delay neurodegenerative diseases and improve cognitive function.

Who is the top pure powdered Naringenin Supplier?

Nutri Avenue, the leading supplier of pure powdered Naringenin! With our commitment to quality and excellence, we provide the finest Naringenin sourced from premium citrus fruits. Our rigorous manufacturing process ensures superior purity and potency, delivering the true potential of Naringenin. Choose Nutri Avenue for your Naringenin needs and unlock the power of nature’s best.


The solvent commonly used for Naringenin extraction is ethanol, a mixture of ethanol and water.

Naringenin is sparingly soluble in water but more soluble in organic solvents like ethanol and methanol.

The bioavailability of Naringenin is relatively low due to its poor absorption and rapid metabolism in the body. However, specific formulations or delivery systems can enhance their bioavailability.

Naringenin is not typically found in significant quantities in grapefruit seed extract. It is primarily present in the peel and pulp of grapefruits.

Naringenin is considered the more active and beneficial form compared to Naringin.

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