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Product Name Oxiglutatione
Other Names Oxidized glutathione, Glutathione disulfide, GSSG
CAS Number 27025-41-8
Molecular Formula C20H32N6O12S2
Molecular Weight 612.63
Applications Personal Care, Dietary Supplements, Functional Foods, Animal Nutrition, etc.
Package 1kg,5kg/bag, 25kg/drum


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What Is Oxiglutatione, and How Is It Used?

Oxiglutatione is an essential cofactor that acts as an inhibitor of free radical formation in the body. Its role in blocking oxidative stress is crucial in preventing various diseases such as heart disease and cancer. Free radicals are harmful molecules that occur when you are exposed to toxins such as tobacco smoke or radiation. As such, the use of Oxiglutatione in inhibiting their formation is a critical factor in maintaining overall health. Oxiglutatione is a potent antioxidant that is synthesized in all human cells. It plays a crucial role in mitigating the harmful effects of free radicals by protecting cells from oxidative damage.

Bulk Oxiglutatione Specification Sheet


Dietary Supplement


White Powder




Kosher, Halal, GMP, etc.

Active Ingredient

Amino acids glycine, Cysteine, Glutamic acid

Test Methods


MOQ (minimum order quantity)



Available (10-20g/bag)

OEM Service

Available, such as capsules, tablets, pills, etc.

ODM Service


Private Label


Contract Manufacturing


General Oxiglutatione Production Process

To initiate the reaction, simply add the enzyme solution to a 50 mM Tris hydrochloride buffer (pH 8.0) that already contains 10 mM ATP, 15 mM L-glutamic acid, 15 mM L-cysteine, and 10 mM magnesium sulfate. Make sure to maintain the temperature at 30°C for optimal results. To halt the reaction, add Γ-glutamylcysteine to the reaction solution. Finally, use high-performance liquid chromatography to accurately quantify the amount of Γ-glutamylcysteine present in the reaction solution. This process will lead to the successful completion of the experiment. GSH I can be sourced from different origins such as microorganisms, animals, and plants. However, GSH I derived from microorganisms is the most desirable option. The most highly preferred sources of GSH I are intestinal bacteria such as Escherichia coli, bacteria like coryneform bacteria, and eukaryotic microorganisms such as yeast.

Oxiglutatione Powder Flow Chart

Health Benefits & Applications

1. Improve Psoriasis

A study was conducted on seven patients who were given a daily dose of a special type of whey protein that increases glutathione levels in the body. After three months, all the patients saw an improvement in their skin, regardless of other treatments they were using. Researchers would like to conduct more large-scale studies to confirm these early positive results.

2. Reduces Stress Oxidation

When molecules undergo oxidation, electrons transfer between them, causing a change in their structure and function. Unfortunately, this process can harm your cells. Luckily, the body has a way to fight this using antioxidant. One such antioxidant is oxiglutathione, which acts like a shield to protect the surrounding cell components from damage caused by oxidation. This causes glutathione to change from its reduced form to its oxidized form.

3. Reduces Liver Damage

The liver is an important organ that helps our body get rid of toxins and breaks down food. However, things like drugs, toxins in the environment, and unhealthy food can damage the liver by creating harmful reactions. To protect itself, the liver produces oxiglutathione, a substance made inside its cells that prevents these harmful reactions.

4. Prevents Aging

The decrease in oxiglutathione levels as we age can cause a significant impact on our body’s antioxidant mechanism, reducing our ability to combat oxidative stress. Oxidative stress is a major factor that leads to cell aging, which makes it crucial to maintain adequate levels of glutathione in the body. By doing so, we can effectively slow down the process of cell aging and protect our bodies from the damage caused by free radicals.

5. Supports Metabolism

Oxiglutathione, an antioxidant, is crucial for the metabolism of essential vitamins and minerals, including vitamins C and E. Its support for nutrient metabolism is vital for maintaining overall health and wellbeing. Nevertheless, it’s important to note that more research is needed to fully understand how glutathione helps in nutrient metabolism.

6. Improves Performance

When muscles are subjected to intense activity, it results in a surge of oxidative molecules, particularly reactive oxygen and nitrogen species. To combat their harmful effects, muscles immediately employ Oxiglutathione as a countermeasure.

 Side Effects and Precautions

When applied topically to the skin, there isn’t enough reliable information to determine the safety of glutathione. However, it’s important to note that it may cause a rash when applied to the skin.

When taken orally, glutathione is safe in doses up to 500 mg per day for no longer than 2 months. Although there is limited information available on its side effects, there haven’t been any significant concerns reported.

When inhaled, oxiglutathione is also considered safe. While information on potential side effects is limited, there haven’t been any significant safety concerns reported.

Is Oxiglutatione FDA-Approved?

It is approved by FDA. The approved medication in reference is Navstel, which is composed of Oxiglutatione as its active component. This medication is known to inhibit glutathione reductase. However, it is to be noted that the chemical structure provided by DrugBank displays opposite stereochemistry when compared to the INN record and the ChEMBL ligand mapped here.

Looking for a Reliable Oxiglutatione Supplier in USA?

Nutri Avenue, as your premier provider of Oxiglutathione powder and top-quality raw ingredient materials in bulk, not only boasts an unparalleled commitment to product excellence but also leverages a robust local logistics advantage. With strategically positioned warehouses spanning California, Florida, and seemingly the New York/New Jersey area, we ensure swift and seamless distribution nationwide. Our local logistics prowess guarantees prompt delivery, allowing us to cater to your needs efficiently and reliably. Trust Nutri Avenue to not only exceed industry standards but also deliver convenience and satisfaction through our unparalleled local logistics capabilities.

If you need high-quality bulk raw powder ingredients, please feel free to contact us and we’ll provide you excellent services.

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