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Semen Aesculi Extract

Product Name Semen Aesculi Extract
Active Ingredients Sodium Aescinate
CAS Number 20977-05-3
Molecular Formula C55h86o24
Molecular Weight 1131.26 g/mol
Applications Personal Care, Dietary Supplements, Functional Foods, Animal Nutrition, etc.
Package 1kg,5kg/bag, 25kg/drum

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Semen Aesculi Extract

What is Semen Aesculi Extract?

This supplement ingredient comes from the seeds of the horse chestnut tree (Aesculus hippocastanum). It is prized for its bioactive compounds, including aescin, flavonoids, and tannins, which offer notable health benefits. The extract is extensively used in personal care, dietary supplements, functional foods, and animal nutrition due to its anti-inflammatory, antioxidant, and venotonic properties. These benefits make it a versatile ingredient across various industries.

Active Ingredients

Sodium aescinate, the active compound in Semen Aesculi Extract, is a potent saponin derived from horse chestnut seeds (Aesculus hippocastanum). It is recognized for its anti-inflammatory, anti-edematous, and venotonic effects. Sodium Aescinate reduces swelling and inflammation by inhibiting enzymes that weaken capillary walls, thereby enhancing capillary permeability and improving blood circulation. It is widely used to treat chronic venous insufficiency, varicose veins, and hemorrhoids. Additionally, Sodium Aescinate effectively relieves pain and swelling from sports injuries and surgeries.

Common Sources

Semen Aesculi Extract, or Horse Chestnut extract, is sourced exclusively from the leaves and bark of Aesculus hippocastanum due to the toxicity of its seeds. Widely used in alternative medicine, this plant is known for its ability to prevent and reduce edema, which involves fluid leakage from veins and capillaries. Traditionally, it has been used to manage edema and related issues, though its exact mechanisms have only recently been scientifically validated. Despite effectively managing symptoms, further research is needed to understand its effectiveness in addressing the diverse causes of edema.

How Does It Work?

Semen Aesculi Extract operates through its anti-inflammatory, antioxidant, and venotonic properties. Its main component, aescin, reduces inflammation by blocking the release of inflammatory substances and reducing capillary permeability. Acting as an antioxidant, it counters free radicals, safeguarding cells against oxidative harm. Furthermore, aescin boosts venous tone, enhancing blood circulation and alleviating symptoms linked to chronic venous insufficiency.

Production Process

Harvesting

Leaves and bark are collected from Aesculus hippocastanum trees during peak seasons to maximize the concentration of bioactive compounds.

Drying

Harvested leaves and bark undergo thorough drying to reduce moisture content, preserving the integrity of bioactive compounds.

Extraction

Dried leaves and bark are extracted using appropriate solvents to isolate desired compounds like aescin, flavonoids, and tannins.

Filtration

The solution is then filtered to purify the extract and remove solid particles, ensuring a pure extract.

Concentration

The filtered extract may undergo concentration methods such as evaporation or distillation to enhance the potency of active ingredients.

Standardization

The extract is standardized to maintain consistent levels of bioactive compounds across batches, meeting quality standards.

Testing

Rigorous quality control tests the extract for purity, potency, and absence of contaminants before approval for use in supplements, cosmetics, or pharmaceuticals.

Packaging

The finalized Semen Aesculi Extract is packaged under controlled conditions to preserve stability and efficacy until distribution.

Bulk Semen Aesculi Extract  Specifications

Type Plant Extract
Appearance Brownish-yellow powder
Purity 98%
Certifications Halal, Kosher, etc.
Active Ingredient Sodium Aesculi
Test Methods Gas Chromatography, HPLC, etc.
MOQ (minimum order quantity) 1kg
Sample Available (10-20g/bag)
OEM Service Available, such as capsules, tablets, pills, etc.
ODM Service Available
Private Label Available
Contract Manufacturing Available

Semen Aesculi Extract: Benefits, Side Effects, And More

For Skin

Semen Aesculi Extract benefits skin health by acting as an antioxidant, neutralizing free radicals to reduce oxidative stress and prevent premature aging. Its anti-inflammatory properties help alleviate redness, swelling, and conditions like eczema. The extract’s tannins also tighten and tone the skin, promoting wound healing and minimizing pore size.

For Blood Vessels

Semen Aesculi Extract has significant effects on vascular health. Aescin enhances vein tone and elasticity, aiding in managing chronic venous insufficiency and varicose veins. It can reduce swelling and pain in blood vessels while enhancing blood circulation, lowering risks of blood clots, and improving overall vascular health.

For Joints

Semen Aesculi Extract benefits joint health by providing relief from conditions like arthritis. It also has the ability to reduce inflammation. It protects joint tissues from oxidative stress, supporting joint health and mobility.

For Digestive Health

Semen Aesculi Extract offers advantages for digestive wellness. Its tannins aid in managing diarrhea by reducing intestinal inflammation and tightening mucosal tissues. The extract’s anti-inflammatory effects also help manage conditions such as irritable bowel syndrome by stopping inflammation in the digestive tract.

Industry Applications and Uses

Dietary Supplements

Semen Aesculi Extract is widely utilized in dietary supplements and is available in capsules, tablets, and powders. It is included in formulations to support vascular health, reduce inflammation, and enhance skin health. The extract’s venotonic and anti-inflammatory properties make it prevalent for supplements that manage chronic venous insufficiency and joint health.

Functional Foods

Semen Aesculi Extract is incorporated into functional foods and beverages for health benefits. It is added to fortified drinks, bars, and snacks to boost antioxidant intake and support vascular health. Nutraceutical products also utilize Semen Aesculi Extract for its anti-inflammatory and venotonic effects.

Personal Care Products

Semen Aesculi Extract is extensively used in personal care products like lotions, creams, and serums. Its antioxidant and anti-inflammatory properties help diminish wrinkles, enhance skin elasticity, and treat conditions like eczema and varicose veins. The extract’s astringent properties contribute to skin tightening and pore reduction.

Standard Dosage and Usage

The typical dosage of Semen Aesculi Extract in dietary supplements ranges from 100 to 300 milligrams per day, available in capsules, tablets, or powder forms. Dosage adjustments can vary based on individual requirements and product specifications. Dividing the daily dose into smaller portions helps maintain consistent levels in the body. For optimal absorption, it is advised that the extract should be taken with a meal containing fat.

Safety and Side Effects

Semen Aesculi Extract is generally safe when taken at recommended doses for short-term use, with no severe adverse effects reported in human studies. However, long-term safety and higher dosage effects require further investigation and should be overseen by a healthcare professional. Minor side effects may include gastrointestinal discomfort (such as nausea or diarrhea), allergic reactions (rarely causing rashes or itching), or mild headaches.

Semen Aesculi Extract vs Rutin

Both Semen Aesculi Extract and rutin are valued for their venotonic and anti-inflammatory properties, yet they differ in mechanisms of action and chemical composition. Rutin, a flavonoid found in various plants, contrasts with Semen Aesculi Extract, derived from horse chestnut seeds and rich in aescin as its primary active ingredient. Both are effective against chronic venous insufficiency, but Semen Aesculi Extract’s astringent properties offer additional benefits.

Semen Aesculi Extract vs Grape Seed Extract

Semen Aesculi Extract and Grape Seed Extract offer antioxidant-rich and anti-inflammatory properties that benefit overall health. Grape seed extract, known for its proanthocyanidin content, supports cardiovascular health and reduces inflammation throughout the body. In contrast, Semen Aesculi Extract contains a high level of aescin, which enhances venous tone and addresses symptoms of chronic venous insufficiency. This unique characteristic of Semen Aesculi Extract makes it particularly effective for improving blood circulation and alleviating discomfort associated with venous issues. While both extracts support vascular health, Semen Aesculi Extract’s targeted benefits for venous tone and chronic venous insufficiency make it a preferred choice for individuals seeking relief from venous-related conditions.

How should this ingredient be stored?

Store Semen Aesculi Extract in a cool, dry place. Store it away from heat and sunlight, ideally in an airtight container to shield it from moisture and air exposure. Ensure the storage area is free from strong odors and chemicals that could contaminate the product. Room temperature storage is suitable, while refrigeration preserves stability and potency for extended shelf life. Follow manufacturer guidelines for optimal storage conditions to maintain product effectiveness.

Where can I find Wholesale Semen Aesculi Extract Supplier?

For wholesale needs, Nutri Avenue is a trusted global supplier of Semen Aesculi Extract. They source high-quality extracts from natural origins, ensuring purity and potency through rigorous testing. Nutri Avenue offers competitive pricing, reliable supply chains, and exceptional customer service and serves various sectors, including dietary supplements, functional foods, personal care, and pharmaceuticals. In addition, we offer diverse customizations like OEM/ODM services for the convenience of supplement manufacturers. Visit their website for inquiries and detailed product information.

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