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Vitamin B12 Powder

Product Name Vitamin B12 Powder
Other Names Cyanocobalamin, Cobalamin, Hydroxocobalamin, Methylcobalamin, Adenosylcobalamin
CAS Number 68-19-9
Molecular Formula C63H88CoN14O14P
Molecular Weight 1,355.37 g/mol
Applications Personal Care, Dietary Supplements, Functional Foods, Animal Nutrition, etc.
Package 1kg,5kg/bag, 25kg/drum


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Vitamin B12 Powder

What Is Vitamin B12 Cyanocobalamin?

Cyanocobalamin, commonly referred to as Vitamin B12, is a water-soluble micronutrient essential for many physiological functions within the human body. This compound belongs to the B-vitamin group and is imperative for the satisfactory operation of the nervous system, the creation of erythrocytes, and the amalgamation of deoxyribonucleic acid.

Cyanocobalamin is the most commonly available form of vitamin B12 and is often used in supplements and fortified foods. It is a synthetic form of the vitamin and contains a cyanide molecule bound to a cobalamin (B12) molecule. Although the cyanide molecule is tightly bound and generally considered safe in small amounts, it is converted into a harmless substance in the body.

Upon consumption, cyanocobalamin undergoes a sequence of biochemical transformations within the human body, ultimately resulting in the liberation of the biologically active forms of vitamin B12, namely methylcobalamin, and adenosylcobalamin. Enzymes within the human body utilize dynamic shapes to perform various crucial functions.

The primary food sources of Vitamin B12 are derived from animal-based products, including meat, fish, eggs, and dairy. Individuals adhering to a rigorous vegetarian or vegan dietary regimen may face an elevated likelihood of experiencing a deficiency in vitamin B12, as plant-derived food sources do not inherently possess substantial quantities of this particular vitamin. Supplements containing cyanocobalamin or other variants of vitamin B12 are frequently suggested in such instances to fulfill the body’s demands.

What Is The Best Form Of B12?

The best form of vitamin B12 can vary depending on individual needs and preferences. Here are the most common forms of vitamin B12 and their characteristics:

  1. Cyanocobalamin: Cyanocobalamin is the most stable and widely available form of vitamin B12. It has an excellent shelf life and is commonly used in supplements and fortified foods. While it is an effective form of B12, some individuals prefer other forms due to concerns about the small amount of cyanide in the molecule. However, the cyanide is converted to a harmless substance in the body.
  2. Methylcobalamin: Methylcobalamin, the biologically active form of vitamin B12, obviates the need for metabolic conversion. There is a prevailing belief that the substance in question exhibits a notable degree of bioavailability and is efficiently assimilated by the body. Methylcobalamin is involved in various biochemical reactions, including methylation processes in the body. It is commonly found in sublingual (under the tongue) B12 supplements.
  3. Hydroxocobalamin: Hydroxocobalamin is another natural form of vitamin B12 that is often used in injectable formulations. It has a longer half-life than cyanocobalamin and can be converted into active forms of B12 as needed. Hydroxocobalamin is sometimes preferred for individuals with certain health conditions or specific requirements.

The “best” form of vitamin B12 depends on individual needs, absorption ability, and personal preferences.

Typical Bulk Vitamin B12 Powder Specifications

Vitamin B12 powder is typically available in various purities depending on the manufacturing process and intended use. Here are some typical purities for Vitamin B12 powder:

  • Vitamin B12 Powder 98%
  • Vitamin B12 Powder 99%
AppearanceFine, crystalline powder
Content≥ 98% (on a dry basis)
Purity≥ 99%
Particle Size≤ 200 microns
Other IngredientNone
CertificationsGMP, ISO 9001
Water Content≤ 1%
Test MethodHPLC, FTIR
MOQ (minimum order quantity)1kg
SampleAvailable (10-20g/bag)
OEM ServiceAvailable, such as capsules, tablets, pills, etc.
ODM ServiceAvailable
Private LabelAvailable
Contract ManufacturingAvailable

What Foods Have Vitamin B 12?

The primary dietary sources of Vitamin B12 are animal-based foods because specific bacteria present in the intestines of animals are responsible for their production. The following are commonly recognized nutritional sources of vitamin B12.

  1. Meat: Beef, pork, lamb, and poultry (such as chicken and turkey) are good sources of vitamin B12. Organ meats like liver are wealthy in B12.
  2. Fish and Shellfish: Fish varieties like salmon, trout, tuna, and sardines contain vitamin B12. Shellfish such as clams, mussels, and crabs are also good sources.
  3. Eggs and Dairy: Eggs and dairy products like milk, cheese, and yogurt contain vitamin B12. However, the content may vary depending on the processing methods and animal diet.
  4. Fortified Foods: Some plant-based foods are fortified with vitamin B12 to provide options for vegetarians and vegans. These may include fortified plant-based milk (soy, almond, etc.), breakfast cereals, nutritional yeast, and meat substitutes.

What Is The Source Of Vitamin B12 Powder?

The source of vitamin B12 powder depends on whether it is a synthetic or natural form of the vitamin. Here are the two primary sources.

  • Vitamin B12 Powder Synthetic

The predominant type of vitamin B12 utilized in dietary supplements and fortified food items is of synthetic origin, commonly derived via fermentation processes. In this process, certain strains of bacteria are grown in large-scale fermentation tanks, and they have vitamin B12 as a byproduct. The vitamin B12 is then extracted from the bacteria and processed into a powder.

  • Vitamin B12 Powder Natural

Natural vitamin B12 is derived from animal sources. It is extracted from animal tissues, such as the liver, through various methods. However, it’s important to note that the production of natural vitamin B12 is more complex and expensive than synthetic production, making synthetic vitamin B12 more commonly used in commercial products.

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What are the benefits of Vitamin B12?

The essentiality of Vitamin B12 in sustaining general health and promoting a state of well-being is of paramount importance. Several notable advantages are associated with the consumption of vitamin B12, including:

  1. Red Blood Cell Formation: Vitamin B12 is necessary to produce healthy red blood cells. DNA synthesis is facilitated by it and plays a role in erythropoiesis within the bone marrow. Adequate levels of vitamin B12 are imperative in preventing specific forms of anemia, including megaloblastic anemia, which may result in symptoms such as fatigue and weakness.
  2. Nervous System Function: Vitamin B12 maintains a healthy nervous system. It helps produce myelin, a protective sheath around nerve fibers, facilitating proper signal transmission. Adequate B12 levels are necessary for optimal nerve function and can help prevent neurological disorders and symptoms such as numbness, tingling, and difficulty with balance.
  3. Cognitive Function: It is widely postulated that Vitamin B12 is implicated in maintaining cognitive function and optimal brain health. Several research studies have proposed a correlation between the inadequacy of vitamin B12 and the deterioration of cognitive abilities, such as memory impairment and the onset of dementia. Adequate B12 levels support healthy brain function and help maintain cognitive skills.
  4. Energy Production: Vitamin B12 metabolizes carbohydrates, proteins, and fats, converting them into usable energy. It helps the body extract energy from food and plays a vital role in maintaining energy levels and reducing fatigue.
  5. DNA Synthesis: Vitamin B12 is necessary to synthesize DNA, the genetic material in all cells. Adequate B12 levels are essential for proper cell division and growth.
  6. Heart Health: Some research suggests that maintaining adequate vitamin B12 levels may help support cardiovascular health. B12, in conjunction with other B vitamins such as folate, is purported to regulate homocysteine levels. Increased levels of homocysteine have been associated with an elevated risk of cardiovascular disease.

Where can you buy bulk VB12 Cobalamin powder online?

Discover the ultimate destination for all your bulk Vitamin B12 Cobalamin powder needs online – Nutri Avenue! We offer premium quality B12 Cobalamin powder in bulk quantities, ensuring you always have this essential nutrient. Nutri Avenue provides a comprehensive selection of B12 Cobalamin products at competitive prices and a user-friendly online shopping platform, making it a convenient destination for all your B12 Cobalamin needs. Nutria Avenue offers an opportunity to enhance your health journey. Shop now to avail the benefits.

What Is Vitamin B12 Powder Manufacturing Process?

Vitamin B12, also called cobalamin, is a hydrophilic vitamin commonly synthesized via bacterial fermentation. The following is a comprehensive outline of the manufacturing procedure for vitamin B12 powder.

B12 powder manufacturing process


Folic acid and vitamin B12 exhibit a strong interrelationship. They collaborate in diverse physiological processes, such as the generation of erythrocytes and the amalgamation of DNA. Sufficient quantities of both vitamins are imperative for achieving optimal health.

The superiority of liquid vitamin B12 over pills still needs to be conclusive. Both modalities can be efficacious, and the selection may hinge on subjective inclination and specific requirements. Individuals may prefer either liquid or pill medication, with some finding the former easier to assimilate and others favoring the latter due to convenience.

The choice between taking vitamin B12 alone or a B complex supplement depends on individual needs. If you have a specific deficiency or require higher levels of B12, taking vitamin B12 alone may be sufficient. However, a B complex supplement provides a combination of B vitamins, including B12, and may benefit overall B vitamin support.

Vitamin B12 (cyanocobalamin) is GRAS by the U.S. FDA. It is available over the counter as a dietary supplement and is widely used in various food products. However, it’s important to note that FDA approval is not required for dietary supplements like vitamin B12. The FDA regulates dietary supplements differently from prescription or over-the-counter medications.

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