Vitamin K2 MK7

What Is Vitamin K2 MK7?

Vitamin K2-MK-7, a subtype of vitamin K2, is a fat-soluble vitamin critical for human health. Unlike Vitamin K1, which is involved in blood clotting, Vitamin K2-MK-7 plays a significant role in bone and cardiovascular health. It is found in fermented foods or animal products and is synthesized by bacteria in the gut. The most potent and bioavailable form of Vitamin K2, MK-7, is well-known for its longer half-life in the human body, providing more extended protection and health benefits than other forms of Vitamin K.

Sources from

• Natto: A traditional Japanese food made from fermented soybeans, natto is one of the richest sources.
• Cheese: Certain cheeses, especially aged varieties, contain substantial amounts of Vitamin K2-MK-7 due to bacterial fermentation.
• Animal Products: Meat, especially liver and eggs, are also good sources.
• Fermented Foods: Other fermented foods like sauerkraut and miso also contribute to Vitamin K2 intake.

Vitamin K2 MK7, like other fat-soluble vitamins, generally appears as a yellow to amber oily liquid or as a powder. Here’s a more detailed look at its appearance in various forms.

Appearance of Vitamin K2 MK7

• Pure Form.

1. Liquid: In its pure form, Vitamin K2 MK-7 is an oily liquid. The color can range from pale yellow to amber.
2. Powder: When processed into a powder form for supplements, it can appear yellowish to off-white.

• Supplement Form.

Capsules: Vitamin K2 MK-7 is often encapsulated in soft gels or hard capsules. These capsules are typically opaque or translucent and may be colored to protect the contents from light exposure, which can degrade the vitamin.

Tablets: It can also be compressed into tablet form. Tablets might be coated to protect the vitamin from light and to ensure stability.

Liquid Supplements: Some liquid supplements may contain Vitamin K2 MK-7 in a solution, usually combined with a carrier oil to aid absorption. These liquid supplements are often packaged in dropper bottles.

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High-quality supplements will clearly indicate the type of Vitamin K2 (MK-7) and its dosage. They may also provide information on the source and any additional ingredients. Look for third-party supplements tested for purity and potency to ensure you’re getting a high-quality product.

All in all, Vitamin K2 MK7 appears as a yellow to amber oily liquid in its pure form and can also be found as a yellowish powder. In supplements, it is commonly encapsulated or formulated into tablets or liquids. Proper packaging and storage are essential to maintain its stability and effectiveness.

How Does It Work?

Vitamin K2 MK7 works by activating proteins that regulate calcium deposition in the body. It activates osteocalcin, a protein that aids in binding calcium to the bones, enhancing bone strength and density. Additionally, vk2 mk7  activates matrix Gla-protein (MGP), which prevents calcium deposition in arteries and soft tissues, thus promoting cardiovascular health. The long half-life of MK-7 ensures prolonged activity in the body, providing continuous benefits over time.

Specification sheet reference

Vitamin K2 MK7 VS MK4

Vitamin K2 has several forms, the most common being MK-4 (menaquinone-4) and MK-7 (menaquinone-7). Both forms have unique properties and benefits, which are important to understand when supplementing.

• Vitamin K2 MK4

Structure and Sources: MK-4 is a short-chain menaquinone found in animal products such as meat, eggs, and dairy.

Absorption and Half-life: MK-4 has a relatively short half-life in the body, around 1-2 hours, which means it needs to be taken more frequently to maintain its levels.

Function and Benefits:

1. Bone Health: MK-4 is known to activate osteocalcin, which is critical for bone mineralization.
2. Cardiovascular Health: MK-4 helps prevent arterial calcification by activating matrix Gla-protein (MGP), which inhibits calcium deposits in the arteries.
3. Other Benefits: Some studies suggest that MK-4 may have additional roles in brain function and cancer prevention.

Dosage: Commonly supplemented in higher doses (e.g., 1-45 mg per day) due to its short half-life and rapid utilization by the body.

• Vitamin K2 MK 7

Structure and Sources: MK-7 is a long-chain menaquinone primarily found in fermented foods, especially natto (fermented soybeans).

Absorption and Half-life: MK-7 has a much longer half-life, approximately 72 hours, which allows for more stable blood levels and less frequent dosing.

Function and Benefits:

1. Bone health: MK-7 effectively activates osteocalcin, aiding calcium binding to the bone matrix.
2. Cardiovascular Health: Like MK-4, MK-7 also activates matrix Gla-protein (MGP), reducing the risk of arterial calcification.
3. Other Benefits: MK-7 may have anti-inflammatory effects and has been shown to improve vascular elasticity.

Dosage: Typically taken in smaller doses (e.g., 90-200 mcg per day) due to its longer half-life and sustained activity in the body.

3 Key Differences Between Vitamin K2 MK7 VS MK4

Half-life: MK-4 has a short half-life and requires more frequent dosing, while MK-7 has a long half-life and maintains steady levels with less frequent dosing.

Source and Bioavailability: MK-4 is found in animal products and is rapidly utilized by the body, whereas MK-7 is found in fermented foods and remains active in the bloodstream longer.

Supplementation Needs: The choice between MK-4 and MK-7 may depend on specific health goals, dietary preferences, and individual response to each form.

Vitamin K2 MK7 And MK4: Combined Supplementation

Some supplements include MK-4 and MK-7 to leverage the unique benefits of each form. This combination can provide comprehensive support for bone and cardiovascular health by ensuring rapid and sustained activation of vitamin K-dependent proteins.

In conclusion, MK-4 and MK-7 have important roles in health, particularly for bone and cardiovascular systems. MK-4 offers rapid utilization, while MK-7 provides longer-lasting effects.

Vitamin D3 VS K2 MK7

Vitamin D3 (cholecalciferol) and K2 Vitamin (menaquinone) are two vitamins that work synergistically in the body, especially in maintaining bone and cardiovascular health. Here’s a closer look at each of these vitamins and their combined benefits.

• Vitamin D3

Function: Vitamin D3 is crucial for calcium absorption in the gut and maintaining adequate serum calcium and phosphate concentrations, which enables normal mineralization of bone and prevents hypocalcemic tetany (involuntary contraction of muscles).

Sources: Sun exposure is a primary source of Vitamin D3. It can also be obtained from fatty fish (salmon, mackerel), fish liver oils, and fortified foods (dairy products and cereals).

Deficiency: Lack of Vitamin D3 can lead to rickets in children and osteomalacia in adults with weak or soft bones.

• K2 Vitamin

Function: Vitamin K2 is essential for the carboxylation of certain proteins required for blood clotting and calcium binding in bones and other tissues. This carboxylation process activates proteins like osteocalcin, which is crucial for bone health.

Sources: Vitamin K2 is found in animal products and fermented foods, such as meat, cheese, and natto (fermented soybeans).

Deficiency: A deficiency in Vitamin K2 can lead to impaired blood clotting, bone weakness, and calcification of arteries and other soft tissues.

Vitamin D3 And K2: Combination Benefits

For Bone health. Vitamin D3 increases calcium absorption from the diet. At the same time, K2 Vitamin ensures that the calcium is deposited in the bones and teeth where needed rather than in the arteries and other soft tissues where it can cause harm.

For Cardiovascular Health. By directing calcium to the bones and preventing its deposition in the arteries, Vitamin K2 helps prevent arterial calcification, a risk factor for cardiovascular diseases.

For Immune Function. Both vitamins support the immune system. Vitamin D3 modulates the immune response, while K2 has anti-inflammatory properties.

Given their synergistic roles, Vitamin D3 and K2 are often combined in supplements. This combination can be particularly beneficial for people at risk of deficiencies or having higher needs due to age, lifestyle, or certain health conditions. Common doses might include 1,000-5,000 IU of Vitamin D3 and 100-200 mcg of Vitamin K2.

It’s important to be aware of potential interactions with other medications, especially blood thinners, since Vitamin K2 can affect blood clotting.

Regular monitoring of blood levels of these vitamins can help ensure optimal health benefits while avoiding toxicity.

In conclusion, combining Vitamin D3 and K2 supplementation can provide significant health benefits, particularly in supporting bone and cardiovascular health.

K2 Vitamin Factory: How To Produce It In Bulk?

1. Fermentation: Soybeans or other substrates are fermented using specific bacterial strains like Bacillus subtilis to produce Vitamin K2-MK-7.
2. Extraction: The fermented substrate is extracted using solvents like ethanol to isolate Vitamin K2-MK-7.
3. Purification: The extract is purified using techniques such as chromatography to achieve high purity levels of Vitamin K2-MK-7.
4. Concentration: The purified ingredient is concentrated using vacuum evaporation to increase potency.
5. Drying: The concentrated extract is dried to a fine powder using spray drying or freeze drying methods.
6. Quality Control: To assure the purity and potency, the final product undergoes rigorous quality control tests, including HPLC and GC.
7. Packaging: The Vitamin K2 MK7 powder is packaged in 1kg, 5kg/bag, or 25kg/drum to maintain stability and shelf life.

Vitamin K2 MK7: Health Benefits, Uses, And More

Bone Health: Vitamin K2-MK-7 enhances bone mineralization by activating osteocalcin, which binds calcium to bones, thus preventing osteoporosis and fractures.

Cardiovascular Health: It prevents arterial calcification by activating MGP, which inhibits calcium deposits in arteries, reducing the risk of atherosclerosis and heart disease.

Dental Health: By promoting the calcification of dental tissues, Vitamin K2-MK-7 helps maintain strong and healthy teeth.

Anti-inflammatory Effects: It exhibits anti-inflammatory properties, which can help reduce inflammation and associated chronic diseases.

Cognitive Function: Some studies suggest that Vitamin K2-MK-7 might support brain health and prevent cognitive decline.

What Is Vitamin K2 MK7 Used For?

Vitamin K2-MK-7 is widely used in dietary supplements to improve bone and cardiovascular health. It is incorporated into functional foods and beverages to enhance nutritional value and promote health benefits.  Vitamin K2 MK7 is used in skin care products for potential anti-aging and health benefits.

Dosage and Usage

For dietary supplements, the standard dosage of Vitamin K2 MK7 ranges from 50 to 200 micrograms per day. It is typically consumed with meals to enhance absorption.

Vitamin K2 MK7 Side Effects: Is It Safe?

K2 Vitamin MK-7 is generally considered safe for most people when taken at recommended doses. It is well-tolerated with no known severe adverse effects. However, potential side effects may include mild stomach issues, such as nausea or diarrhea, particularly at higher doses.

How To Store Vitamin K2 MK7 Powder?

Vitamin K2 MK-7 is sensitive to light, so supplements are often packaged in dark-colored bottles or opaque materials to protect from light exposure.

In order to maintain potency, it should be stored in a cool, dry place away from direct sunlight and excessive heat.

Always follow the manufacturer’s storage instructions to ensure the product remains effective and has a long shelf life.

Wholesale Vitamin K2 MK7 Supplier: Nutri Avenue Inc

As an FDA-registered dietary supplement ingredient supplier, Nutri Avenue stands at the forefront of the global market for wholesale vitamin k2 mk7 powder. We ensure superb quality, purity, and potency through rigorous third-party testing of our natural ingredients. Our extensive infrastructure, featuring five strategically located warehouses in the United States, guarantees reliable supply chains and convenient client access.

Nutri Avenue offers large quantities of ingredients at competitive wholesale prices and accommodates diverse shipping needs via sea, air, and international express. Our comprehensive services include OEM and ODM options, allowing us to customize raw materials into finished products tailored to specific ingredient formulas or functional requirements. Esteemed across various sectors – dietary supplements, functional foods, personal care, etc. – Nutri Avenue is synonymous with exceptional customer service.

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