Nicotinamide Riboside

What Is Nicotinamide Riboside?

Known as an alternative form of Vitamin B3 or Niacin, Nicotinamide riboside is a popular compound believed to increase nicotinamide adenine dinucleotide (NAD+) levels in the human body. This is because the compound, once introduced into the body through supplementation, is converted into NAD+. As a helper molecule, NAD+ maintains certain processes of vital organ systems, thereby preventing their damage and rapid wear and tear.

While experts say that NAD+ can be increased to promote health and wellness by consuming its natural food sources such as dairy products, fish, and mushrooms, taking supplement products with compounds such as nicotinamide riboside can boost healthy aging and support the normal function of the human body.

What Does Nicotinamide Riboside Do?

Health supplement products with NR are usually indicated to prevent rapid aging, which is one of the factors affecting the onset of disease processes. It is believed that this compound provides the said benefit by serving as a precursor to NAD+. NAD+ supports many processes in the body, including repairing damaged DNA and maintaining the body’s immune system. It is also established in health studies that the compound is necessary for converting food into energy. NAD+, however, reduces in quantity with age.

The gradual decrease of NAD+ in the body is a natural phenomenon. Thus, it is necessary to prevent deterioration and compromise of bodily processes.

But in fact, the market’s mainstream is selling nicotinamide riboside chloride polvere, which is a chloride form of nicotinamide riboside (nr). There is almost no such product as nicotinamide riboside powder on the market. Why? Here is the answer.

Nicotinamide Riboside Chloride VS Nicotinamide Riboside

NRC is more stable than NR. NR is very easily oxidized. After bulk powder is opened, if it is not sealed in time, it will be oxidized soon and even change color. It can easily affect ingredient powder quality.

So, chloride is added to Nicotinamide Riboside, but the function of the ingredient is the same. The aim just makes the product more stable. It is also more conducive to processing.

Specification sheet reference

Because NR is easy to oxidize, factories and manufacturers will add Chloride to this powder to increase its stability. This is also convenient and ensures customers will not be troubled and lost due to quality problems when purchasing and applying this ingredient powder.

Nicotinamide Riboside Chloride (CAS number: 23111-00-4) is the mainstream form of NR sold in the market. The most famous market specification is 99% purity.

Nicotinamide Riboside Chloride Benefits

It is a form of chloride salt. Aside from increasing NAD levels, the compound is believed to activate certain pathways which help promote weight loss and address conditions associated with a high-fat diet. The compound is a potent synergized form, also sold in the market for optimal body function.

Niacinamide VS Nicotinamide Riboside

Niacinamide (Nicotinamide) and nicotinamide riboside (NR) are both forms of vitamin B3, but they work differently. The former is primarily used in skin care, with anti-inflammatory, anti-aging, and moisturizing effects while also supporting cell health and energy metabolism. However, its effect in increasing NAD+ levels is milder. NR is more effective in increasing NAD+ in the body, helping fight aging, promoting cell energy metabolism, and improving overall health. It is particularly suitable for products seeking to improve cell health and slow aging.

Nicotinamide Riboside VS Niacin

Although both are known to increase NAD levels, studies show their effects on the human body may vary. At the outset, NR is a derivative of Nicotinamide. One study supports the claim that Nicotinamide is more similar to NAD than Niacin and is associated with lesser risks when used to treat skin conditions.

In leading health studies, it is observed that Niacin supplementation causes skin flushing among patients with Pellagra, otherwise known as Vitamin B3 deficiency. Although experts say skin flushing is not alarming and is not associated with inflammation, it is still a side effect.

On the other hand, NR supplementation for Vitamin B3 deficiency does not cause any associated side effects. Health experts also prefer NR as it has longer bioavailability than niacin.

One research also shows that nicotinamide riboside may prevent acne. This benefit is not necessarily found in Niacin supplementation.

Nicotinamide Riboside VS NMN

Experts consider efficiency-wise, NR as supreme over Nicotinamide Mononucleotide, otherwise referred to as NMN. Its CAS number is 1094-61-7, and its molecular formula is C₁₁H₁₅N₂O₈P.

While both compounds act as precursors for NAD+, studies have observed that NR is smaller than NMN. This means that the delivery of Nicotinamide Riboside to body cells is more efficient, especially in supporting mitochondrial processes for cellular energy. As a result, NR promotes longevity in cells and muscles more than NMN.

The latest news about NMN, the FDA banned NMN from being sold as a dietary supplement in 2022/11.

Nicotinamide Riboside: Benefits, Side Effects, And More

The increase of NAD+ through Nicotinamide Riboside supplementation produces natural benefits, as revealed in studies and confirmed by product reviews.

One study found that increasing NAD+ prevents various neurologic conditions linked with the degeneration of brain cells. Hence, it is said that NR may be helpful for patients searching for a preventive measure for Alzheimer’s disease and Dementia.

It is also among the enzymes that fuel energy delivery to various parts of the human body. Thus, it may help promote weight loss among individuals who engage in healthy exercises as it boosts energy and prevents related rapid deterioration of cells.

Animal studies also show that Nicotinamide Riboside and Resveratrol togehther can help prevent cardiac cell damage and improve the powder’s brain-protective effects. This also promotes blood circulation and enhances DNA repair.

The increasing interest in NR has become the subject of many research studies conducted on humans and animals. Among the subjects of today’s research are NAD and nicotinamide adenine dinucleotide + hydrogen or NADH and their effects on maintaining the body’s energy production rate through the ATP mechanism. One research established that higher NAD to NADH ratio is more beneficial to humans than the other way around. Thus, it is recommended by health experts for persons to take Nicotinamide Riboside supplements for better health, as it is a so-called NAD precursor.

Dosage: Is It Safe?

The daily dose for adults for Nicotinamide Riboside powder supplement is 1000-2000mg. When taken within this range, no side effect relative to the product is expected, except among individuals suffering from certain conditions.

Understanding that various related factors must be considered in developing the proper dosage for Nicotinamide Riboside supplementation is essential. These factors include the person’s age, current vitamins and medications being taken, weight, and current health condition.

Is Any Side Effects?

Other than mild gastric effects like nausea and indigestion, Nicotinamide Riboside supplementation has no known side effects when taken within recommended doses. However, when the product causes difficulty breathing or other symptoms affecting the respiratory tract, especially among persons of advanced age, it should be discontinued, and the patient must be brought to a physician.

How To Store This Powder?

Depending on the shop and supplier, bulk nicotinamide riboside chloride powder can be available with free shipping services. The powder is usually packed in a double-sealed PP bag for transport protection.

The compound is not shelf-stable at high temperatures. Thus, it must be stored in cool and dark places after purchase, especially among individuals who live in humid environments.

Nicotinamide Riboside And Pterostilbene: A Powerful Duo for Cellular Health and Longevity

One of the key compound combinations for the body’s effective muscle and DNA repair is Nicotinamide Riboside and Pterostilbene. Among athletes and bodybuilders who often engage in energy-boosting exercises, muscle wear, and tear is always a problem. Studies on animal subjects suggest that NR supplementation combined with Pterostilbene is the key to muscle cell repair and regeneration. Pterostilbene also augments the intended effect of Nicotinamide Riboside supplementation, primarily for healthy aging.

Best NR Nicotinamide Riboside Supplier: Nutri Avenue

If you are looking for a one-stop shop for supplement ingredients like Nicotinamide Riboside and its chloride form, the best source for bulk purchase is Nutri Avenue.

Our company offers a wide variety of products at an affordable price. It is also a registered ingredient supplier with the FDA and is a well-known product distributor.

For more information about Nutri Avenue, you may visit our website. Technical support is also available when checking our page.

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