Trans resveratrol and resveratrol are two isomers. They have similar chemical structures but slightly different molecular configurations. Specifically, their benzene rings are bonded differently, which gives them different physical and chemical properties. Today, Nutri Avenue will talk about these two ingredients. Among supplements, do I need Trans Resveratrol or Resveratrol?
Natural Resveratrol: It Has 2 Major Isomers.
Resveratrol is a non-flavonoid polyphenol compound with a strong biological activity of stilbene structure. It is mainly derived from grapes, including skins and seeds, knotweed, peanuts, mulberries, and other plants. It not only has some common characteristics of plant polyphenols but also has unique biological activities. Among them, Polygonum cuspidatum, a Chinese medicinal material, has a higher resveratrol content.
Initially, the ingredient was found in red wine, but in very small amounts. It is generally believed that Pinot Noir wine with the highest content contains only 1 to 2 mg per bottle. Here is a comparison. If you need to take resveratrol supplements, it is generally believed that the daily dosage should be at least 500mg. The content of peanuts is even less. Therefore, the raw materials of natural resveratrol powder on the market are generally extracted and prepared from grapes.
Its chemical name is (E)-3,5,4-trihydroxystilbene. The molecular formula is C14H12O3, and the relative molecular mass is 228.25. Natural resveratrol appears as white true crystals. This ingredient is easily soluble in organic solvents like ether, chloroform, methanol, ethanol, acetone, acetic acid, and ethyl ester. But it is difficult to dissolve in water. Its melting point is 253-255℃.
It can produce fluorescence under ultraviolet light irradiation with a wavelength of 365nm. It turns blue when exposed to ferric chloride-potassium ferricyanide solution and red when exposed to alkaline solutions such as ammonia. Resveratrol powder is unstable to light. Trans-resveratrol is stable in ethanol for several months when completely protected from light. The stability is slightly reduced only at high pH (≥10). However, cis-resveratrol is only stable in a neutral environment when protected from light. It can be seen that different forms of resveratrol have different stabilities under different conditions. Therefore, when analyzing resveratrol content, it is recommended that the reference solution and sample solution be prepared and used together.
3 Key Benefits Of Resveratrol Powder
Resveratrol is a polyphenolic compound found naturally in some plants and has been shown to have various biological activities, such as antioxidant, anti-inflammatory, anti-platelet aggregation, etc. These biological activities are believed to prevent and treat various diseases, such as cardiovascular disease, diabetes, tumors, etc.
One is the protective effect on the cardiovascular system.
As the incidence of cardiovascular disease increases year by year, the cardiovascular protective effect of resveratrol has become a research hotspot. It can play a cardiovascular protective role by reducing myocardial ischemia-reperfusion injury, inhibiting atherosclerosis formation, anti-inflammation, antioxidant, vasodilation, etc.
The second is the antibacterial effect.
Resveratrol is known as a plant antibacterial agent produced by grape plants when they are affected by adverse conditions such as fungal infection and ultraviolet radiation.
The third is a natural oxidant.
This ingredient mainly works by scavenging or inhibiting the generation of free radicals. Inhibit lipid peroxidation to achieve antioxidant effect. It promotes skin cell renewal. It also promotes the proliferation of collagen, fibroblasts, and epidermal glial cells. In turn, it increases skin elasticity. Finally, achieves an anti-aging effect. Resveratrol mimics tyrosine. It reduces melanin production by depleting the activity of tyrosine. The final result is fairing and glowing skin.
2 Major Isomers Of Resveratrol: Cis-resveratrol And Trans Resveratrol
Resveratrol exists in free form and glycoside form under natural conditions. The chemical structures of resveratrol and its glycosides also include two isomers, cis and trans, namely cis-resveratrol (cis-Res), trans resveratrol (trans-Res) and cis-resveratrol (trans-Res). Resveratrol glycoside (cis-PD), trans-resveratrol glycoside (trans-PD). The latter two forms release resveratrol under the action of glycosidase enzymes in the intestine. Resveratrol mainly exists in the form of trans isomers in plants. Research shows that Trans Resveratrol is more biologically active than cis. It is an important phytoalexin found in grapes. Some scholars believe that the trans isomer of resveratrol is an important component in preventing and treating atherosclerosis and coronary heart disease.
Who Should Not Take Resveratrol?
- Patients with blood disorders that may cause bleeding.
- People undergoing surgery should stop taking it two weeks before surgery. Also, don’t take it for two weeks after surgery to decrease the risk of bleeding.
- Do not take resveratrol supplements while pregnant or breastfeeding. There is a lack of research demonstrating safety in this area.
- Resveratrol has mild estrogenic activity. Therefore, use with caution in women with cancer and other estrogen-sensitive conditions.
- Children should avoid use.
- Resveratrol can reduce the activity of enzymes involved in drug metabolism. However, whether it has a significant effect on humans has not been studied.
Conclusion: Trans Resveratrol Has High Biological Activity.
Natural resveratrol is a polyphenolic bioflavonoid antioxidant. Trans resveratrol is an isomer of resveratrol. Moreover, it is a form with strong biological activity. Therefore, the resveratrol powder provided by ニュートリ・アベニュー is mainly trans resveratrol. In addition to naturally extracted products, we also offer a synthetic version of this ingredient prepared through fermentation. Both preparation processes can achieve a high purity of 98%. Welcome to inquire about more product documents.
