Simply Know What Soy Isoflavones Is

soy isoflavones

Simply Know What Soy Isoflavones Is

Soy isoflavones are flavonoids found in soybeans. Daidzein and Genistein are two of the most common ingredients. Today, Nutri Avenue will introduce what Soy Isoflavone is. What are Daidzein and Genistein, respectively? Which one is better?

What Is Soy Isoflavones?

Soy Isoflavones is a phytochemical. It belongs to plant flavonoids. It is mainly derived from pods of leguminous plants, especially in soybeans, with a high content of 0.1%-0.5%.

Soy Isoflavones Types

The main structural form of Soy Isoflavones is a group of compounds with 3-benzopyrone as the parent core. There are a total of 12 kinds of natural Soy Isoflavones, which can be divided into three categories, namely Daidzin groups, Genistin groups, and Glycitin groups. Each type exists in four forms: free form, glucoside form, acetyl glucoside form, and malonyl glucoside form. Free Aglycon accounts for 2%-3% of the total, including Genistein, Daidzein, and Glycitein. Bound Glycosides account for 97%-98% of the total and mainly exist in Genistin, Daidzin, 6”-O-malonylGenistin, and 6”-O-malonyl daidzin. They account for about 95% of the total.

Pure soy isoflavones are colorless crystalline substances. Genistein is a colorless, flaky crystal. Daidzein is a colorless needle-shaped crystal. Industrially, soy isoflavone products are white or light yellow powder. Soy isoflavones are related to the bitter taste and astringency of soy products. The free aglycones, especially Genistein and Daidzein, have stronger unpleasant flavors than their glycoside compounds.

What Is Daidzein?

Daidzein, also known as Daidzein, Daidzein, and Daidzein, appears as a white to off-white crystalline powder. This component is soluble in ethanol and ether. It is present in the roots of Pueraria lobata (Willd) Ohwi, Trifolium pratense L., and the whole plant of Medicago sativa L. Daidzein’s CAS number is 486-66-8. Its molecular formula is C15H10O4, and its molecular weight is 254.237 g/mol.

Daidzein VS Daidzin

Daidzin, also known as Daidzoside, appears as a white powder. Its CAS Number is 552-66-9. Its molecular formula is C21H20O9, and its molecular weight is 416.3781 g/mol. It is mainly extracted from the yellow seed coat of Glycine max(L) merr.

Daidzein is a form of soy isoflavones. It is a natural isoflavone compound found in leguminous crops such as soybeans. Soy isoflavones are produced as secondary metabolites during soybean growth. It is mainly located in the cotyledons and hypocotyls of soybean seeds. Soy isoflavones exist in glycoside form. Daidzein is the form that exerts its main functional activity. Daidzin is the glycoside form of daidzin.

What Is Genistein Powder?

Genistein, also known as 5,7,4’-trihydroxyisoflavone, is mainly found in the leguminous family. Common sources include the roots of Genista tinctoria Linn., Sophora Subprostrala Chun et al., etc. Its CAS number is 446-72-0. Its molecular formula is C15H10O5, and its molecular weight is 270.24 g/mol. The appearance of Genistein is gray-white dendritic needle crystal powder. It is almost insoluble in water. But soluble in dilute alkali. On the market, the common specification is 98% purity.

Genistein is the most active type of isoflavone. It is a single ingredient. It is a non-estrogenic compound with weak estrogen-like effects. This ingredient is widely used in pharmaceuticals, health products, and other fields.

Daidzein VS Genistein: Which One Is Better?

Genistein and its aglycone are the most abundant components of soy isoflavones. The aglycone form of soy isoflavones is more active than the glycoside form, especially Genistein. Genistein is one of the main active factors in soybean abnormal flavonoids. It is the most effective functional ingredient in soybean isoflavone products and has a variety of physiological functions.

Soy isoflavones mostly exist in the form of various glucosides. They can have strong physiological functions when these glucosides are hydrolyzed in the body to form aglycones. Research shows that in the human body, soy isoflavone aglycone’s absorption rate and amount are much greater than that of its glycoside form. Among them, Genistein is more active.

Additionally, studies have shown that Genistein degrades at higher temperatures and alkaline pH (9). Meanwhile, Daidzein showed a 15% reduction at 120°C and pH 9. It was observed that Daidzein is 40% less stable than Genistein at neutral pH. Compared to Genistein, the concentration is reduced by 22%.

Therefore, Genistein powder may be a better choice.


Animal experiments show that soy isoflavones have weak estrogenic, antioxidant, anti-hemolytic, and antifungal activity. It can effectively prevent and inhibit the occurrence of leukemia, osteoporosis, colon cancer, lung cancer, gastric cancer, breast and prostate cancer, menopausal syndrome, and other diseases, especially breast cancer and prostate cancer. Therapeutic effect. Among them, Genistein powder is the most active and stable form.

Nutri Avenue recommends Genistein powder. Welcome to contact us for more product details and the latest quotation.

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