In recent years, Rutin powder has become very popular in the US market. Many people may not be very familiar with this ingredient. However, the market awareness of quercetin is a little higher. Is there any relationship between these two ingredients? What is the difference between Rutin and Quercetin? Nutri Avenue will introduce these two related ingredients today.
What Is Rutin?
Rutin, also known as rutin and quercetin, is a flavonoid compound with many sources. It mainly exists in the flower buds and fruits of Sophora Japonica L., namely Sophora Japonica L. and Sophora Japonica L. Its content can reach 20%. At the same time, it is also called vitamin P. Rutin can be decomposed by adding water when encountering strong acidity and alkalinity. The color is unstable in alkaline foods. In ethanol, this ingredient can improve the light resistance of pigment preparations and prevent the gradual disappearance or change of fragrance. Additionally, it has antioxidant capabilities. Combined with vitamin E, etc., it can improve its antioxidant capacity.
Flavonoids play a decisive role in treating cardiovascular and cerebrovascular diseases, of which rutin is a typical representative. It can purify blood vessels, improve circulation, and relieve arthritis symptoms.
During COVID-19, as a preventive measure, rutin can reduce viral damage to achieve cardiovascular protection and anti-inflammatory effects. It also promotes collagen production. If rutin is taken together with Vitamin C, it can also help the body better absorb and utilize these nutrients.
Rutin Powder Benefits
- It promotes heart health.
A 2018 study found that it suppresses heart disease by signaling to specific protein kinases, ERK1/2 and Akt. Using rutin helps reduce the size of necrotic tissue in the hearts of pigs with heart disease. And suppress urine protein concentration and improve blood circulation.
- It relieves arthritis symptoms.
Animal studies have shown that this antioxidant can suppress acute and chronic inflammation, making it a potential natural treatment for arthritis.
Russian researchers found it reduces the excessive production of free radicals in rheumatoid arthritis.
Additionally, a 2017 study found that this ingredient improved joint surface tissue formation, improved cartilage and bone erosion, and reduced inflammation. It also suggests that it has a protective effect against rheumatoid arthritis.
- It assists in the fight against cancer.
Due to its antioxidant and anti-inflammatory effects, it can aid in the fight against cancer. It has also been shown to induce apoptosis, or cancer cell death, and exhibit anti-tumor effects. Flavonoids can sensitize cancer cells to anticancer drugs and improve drug resistance in cancer patients. A scientific review of rutin’s pharmacological potential found that the flavonoid exhibits anticancer effects against several cancers, including leukemia, colon, colorectal, melanoma, liver, and lung cancer.
A study published in Phytotherapy Research found that this phytochemical acts as a chemosensitizer on two human breast cancer cell lines.
Rutin significantly increases the anticancer activity of anticancer drugs and helps halt cell cycle progression. Another study published in Science World Magazine found that it helped fight neuroblastoma. It is a common cancer of the adrenal glands in children. It induces apoptosis and regulates the expression of genes related to apoptosis.
- It protects brain health.
Research shows that rutin has protective effects against brain damage and age-related injuries. Due to its anti-inflammatory and antioxidant properties, it also promotes brain health.
In 2018, research published in Oxidative Medicine and Cellular Longevity showed that bioflavonoids are promising neuroprotective compounds. It is used to treat neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease.
Researchers believe it protects brain health by reducing pro-inflammatory cytokines, improving antioxidant enzyme activity, and restoring the activity of mitochondrial complex enzymes in cells.
- It prevents blood clots.
Researchers at Harvard University found that rutin inhibits protein disulfide isomerase. PDI is rapidly secreted from platelets and endothelial cells during thrombosis. By blocking the secretion of PDI, the ingredient blocked the formation of blood clots in the arteries and veins of mice. It is said to be the only drug that can prevent both types of blood clots.
Rutin VS Quercetin: What Is The Relationship Between Them?
Rutin powder is a glycoside of the flavonoid quercetin. It comes from a combination of quercetin and the disaccharide rutin. In fact, it’s sometimes called purple quercetin.
Quercetin is also a flavonoid antioxidant. It is found in berries, broccoli, and leafy green vegetables. The benefits of this ingredient, similar to rutin powder, include fighting oxidative stress, reducing inflammation, improving cardiovascular health, promoting circulation, and reversing cognitive impairment.
Another study in 2014 found that a combination of rutin and quercetin reduced the cardiovascular effects of hypertension in rats. Even more surprising, the combination of rutin and quercetin was more effective than nifedipine, a drug used to treat high blood pressure and chest pain.
How To Convert Rutin Powder To Quercetin?
First, the collected sophora buds are steamed, dried, crushed, and percolated.
Then, it undergoes flocculation and clarification to remove gum and chlorophyll impurities.
Next, antioxidants and complexing agents are used to protect the complexing process, mixed acid is added to adjust to acidity, and quercetin is hydrolyzed by heating and pressure.
The re-refining process of crude rutin shortens the process flow and reduces production costs. The content of the finished products produced after one-step hydrolysis reaches international standards. The content of quercetin detected by high-performance liquid chromatography (HPLC) can reach more than 95%.
Conclusion: Is Rutin Powder One Of The Best Quercetin Substitutes?
Rutin and quercetin can both be extracted from Sophora Japonica Extract. A molecule of rutin, minus a molecule of rhamnose and glucose, becomes quercetin. In other words, quercetin is the aglycone of rutin. In other words, rutin powder is hydrolyzed to produce quercetin. So, rutin could be one of the quercetin substitutes to bring products with the same functions.
Therefore, 뉴트리 애비뉴 recommends that customers who need quercetin can also learn more about the ingredient rutin powder.
