L-Norvaline: A Valine Isomer for nitric oxide boosting Muscle Mass Growth

L-Norvaline is a popular pre-workout ingredient known to help promote muscle mass development

L-Norvaline is a popular pre-workout ingredient known to help promote muscle mass development by increasing workout performance and decreasing recovery time in between workouts. Many users claim that the compound helps produce more energy and prevent exhaustion. It is also shown in studies that the compound may work in the management of Alzheimer’s disease and other degenerative conditions affecting the brain.

What is L-Norvaline?

L-Norvaline is a compound classified as a non-proteinogenic unbranched-chain amino acid. It is an isomer of the valine which plays a vital role as a bacterial metabolite. The compounds are primarily used in the formulation of dietary supplements for athletes and bodybuilders as it is believed to increase nitric oxide production in the body which, in turn, results in an improvement in overall workout performance. Aside from its independent effects in increasing nitric oxide levels, experts say that the compound may also promote wellness by supporting arginine levels in the body.

L-Norvaline is also commonly known as Norvaline; L(+)-Norvaline; L(+)-2-Aminovaleric acid,2-Aminopentanoic acid, 2-Aminopentyric acid, α-Aminopentanoic acid, and Propylglycine. It is identified as having CAS number 6600-40-4 and molecular formula C5H11NO2. The molecular weight of the compound is 117.15 g/mol.

In dietary supplement products, L-Norvaline appears as a fine white crystalline powder. It is generally soluble in water.

L-Norvaline forms and specifications

L-Norvaline in dietary supplement formulations comes in powder forms with a 99% purity assay based on high-performance liquid chromatography. L-Norvaline powder 99% is available for purchase at various ingredient suppliers offering services online such as Nutriavenue.

Customers may purchase the product in bulk or in lesser quantities. In case of bulk purchases from Nutriavenue, the compound may be packed in 25-kilogram paper drums, with two layers of poly bags inside for added protection. Other packaging options may also be availed of as per request.

Difference between L-valine and L-Norvaline

L-valine is a branched-chain amino acid that is useful in the biosynthesis of proteins. L-Norvaline is an isomer of L-valine. Hence, although these compounds have identical molecular formulas, their molecular structure and atomic positions differ.

In terms of health benefits, both L-valine and L-Norvaline are known to improve musculoskeletal health. However, in terms of potential effects against Alzheimer’s disease, studies on L-Norvaline benefits are more extensive than that of L-valine.

Difference between L-Norvaline and Norvaline

The terms L-Norvaline and Norvaline are essentially used interchangeably to refer to the same compound. However, they differ in that L-Norvaline is a stereoisomer of Norvaline labeled as L or left-handed. The L forms of amino acids like Norvaline are the forms that are mostly used in mammals.

Foods containing L-Norvaline

As a Valine isomer, it is believed that L-Norvaline can also be obtained from food sources of Valine. Valine is found in whole grains, mushrooms, soy, cheese, and vegetables. Beef, chicken, pork, and fish are also good sources of Valine and L-Norvaline.

L-Norvaline and L-citrulline malate

L-citrulline malate is another essential workout compound that consists of Citrulline and Malate. When taken in the human body, Citrulline is converted into L-arginine.

Essentially, both L-Norvaline and L-Citrulline Malate are significant compounds that raise L-arginine levels. Hence, they contribute to muscle mass development and energy production.

L-Norvaline vs Agmatine sulfate

Agmatine sulfate is a compound believed to increase Nitric Oxide. It has comparative benefits with L-Norvaline and Arginine. However, while Norvaline is converted into Arginine in the human body, Arginine is converted into Agmatine. Hence, Agmatine is a metabolite of Arginine.

L-Norvaline safety

In recent years, concerns over the use of L-Norvaline were raised following findings in studies that it may cause neurodegenerative diseases and even cause mitochondrial damage with long-term use. However, in a study published in the US National Library of Medicine National Institutes of Health dated December 17, 2019, and entitled “Reports of L-Norvaline Toxicity in Humans May Be Greatly Overstated”, it was argued that the quantities of L-Norvaline used in the study claiming its toxicity was greatly above cytotoxic levels for all amino acids. Hence, it was concluded in the said study that as long as L-Norvaline is taken within recommended doses, it will not necessarily cause cytotoxic effects.

How do L-Norvaline works?

It is believed that L-Norvaline provides health benefits primarily by regulating Nitric Oxide levels and improving blood flow towards the bones and muscles during the performance of exercises. In effect, oxygen and nutrient supply towards affected muscle regions are increased and exhaustion and fatigue are reduced. This also results in the shortening of recovery time as the muscles can receive nutrient supply efficiently.

L-norvaline, l-ornithine and l-arginine combination

The combination of L-norvaline, l-ornithine, and l-arginine in dietary supplement formulations is claimed to synergize the individual effects of the compounds in promoting muscle cell growth. It was also found that the said compounds may significantly help decrease cognitive decline among individual users.

L-Norvaline Benefits

The following are some of the benefits of using L-Norvaline:

It increases nitric oxide levels

L-Norvaline increases nitric oxide levels

An increase in nitric oxide levels results in vasodilation or widening of the blood vessels. Hence, blood supply towards a certain body area, specifically, the muscle regions, is enhanced with increased nitric oxide levels. L-Norvaline is known to improve nitric oxide levels among individual users.

It is useful for bodybuilding

The compound has long been claimed to promote muscle mass growth and development among bodybuilders and athletes. This is because it increases nutrient and oxygen supply towards muscle groups during workouts.

It may be useful for erectile dysfunction

The increase in nitric oxide levels with L-Norvaline supplementation is likewise believed to help treat erectile dysfunction. This is because the compound increases blood flow towards the genitals during a sexual engagement, thereby possibly preventing erectile dysfunction.

Other benefits

In some studies, it was established that L-Norvaline may have antihypertensive properties. Hence, it may be useful in preventing strokes and myocardial infarction brought about by vasoconstriction.

L-Norvaline side effects

Mild gastrointestinal symptoms such as stomach irritation, nausea, and vomiting may result from L-Norvaline supplementation. Nonetheless, these symptoms are expected to eventually disappear. In cases where these symptoms progress or when other adverse symptoms develop, users should discontinue the use of the supplement and immediately consult a physician.

L-Norvaline dosage

Typically, experts recommend the use of L-Norvaline at 100 to 250 mg per day. However, a physician may prescribe a different dose depending on the individual user’s weight, age, and overall physical condition.

Where to buy bulk L-Norvaline powder?

L-Norvaline powder in bulk is available at Nutriavenue, an FDA-registered ingredient supplier which offers high-quality products at very affordable prices. Our company is also recognized by entities like Halal, Kosher, and GMP.

We also offer shipping services through the air, sea, or couriers like UPS and FedEx. For more information on our products and services, you may contact our technical support staff when you visit our website.

You may also avail of a free quote on our page.

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