Magnesium L-Threonate Powder: Is It Good For Hair Loss?

Magnesium L-Threonate for hair loss

Magnesium L-Threonate Powder: Is It Good For Hair Loss?


Because of the patent problem about Magnesium L-Threonate in the USA, Nutri Avenue has decided not to sell Magnesium Threonate powder from now on. We’re so sorry for the inconvenience caused to you. Once there is the latest news, we will update and inform you in time.

The following information is available for you who are interested in this ingredient to study and research. If you want to know more, please contact us.


Hair loss is becoming a common concern for many younger and older individuals. And it will be a source of significant distress in the following years. This issue can be attributed to different factors, including genetic predisposition, hormonal fluctuations, and inadequate nutrient intake.

The global hair loss market has been growing steadily over the years due to various reasons. For example, the increasing prevalence of hair loss issues, rising awareness about available treatment options, and technological advancements. According to the data by Grand View Research, the global market size of hair loss was valued at $8.8 billion in 2020. And it is expected to expand at a CAGR of 6.8% from 2021 to 2028.

In recent years, there has been a growing demand for natural and organic hair loss products as consumers become more conscious about the ingredients on their hair and scalp. Additionally, there is an increasing trend of personalized hair loss treatments, where companies offer customized solutions based on an individual’s specific hair loss condition.

And now, a potentially effective remedy that shows promise is a distinctive dietary supplement ingredient – Magnesium L-Threonate. This compound, known for its ability to cross the blood-brain barrier, has been gaining attention for its potential benefits for hair health.

A Brief History Of Magnesium L-Threonate

The narrative surrounding Magnesium L-Threonate commences with a collective of researchers affiliated with the esteemed Massachusetts Institute of Technology (MIT). They searched for a form of magnesium that could effectively increase the brain’s magnesium levels. The result was a compound that achieved this goal and showed potential benefits for cognitive function. This discovery marked a significant advancement in the field of nutritional neuroscience.

However, the potential benefits of Magnesium L-Threonate extend beyond the brain. More recently, researchers have begun to explore its effects on other aspects of health, including hair health. It has led to a surge of interest in Magnesium L-Threonate as a potential solution for hair loss.

The Science Behind Magnesium L-Threonate And Hair Loss

Magnesium is a vital dietary component pivotal in numerous physiological processes, including protein synthesis, neuromuscular activity, glycemic management, and cardiovascular homeostasis. It’s also involved in the structural development of bone and is required for synthesizing DNA, RNA, and the antioxidant glutathione.

Magnesium’s role is less well-known regarding hair health. A previous study claimed that dihydrotestosterone (DHT)-induced dickkopf-1 (DKK-1) expression is one of the critical factors in androgen-enhanced alopecia. In addition, studies have demonstrated that L-ascorbic acid 2-phosphate (Asc 2-P) inhibits DHT-induced DKK-1 expression in cultured dermal papilla cells (DPC).

Here, we investigated whether Magnesium L-Threonate could attenuate DHT-induced DKK-1 expression. We observed attenuation of DHT-induced DKK-1 expression in the presence of it by RT-PCR analysis and ELISA. We also found that DHT-induced activation of DKK-1 promoter activity was significantly inhibited by L Threonic acid. Additionally, a co-culture system featuring outer root sheath (ORS) keratinocytes and DPCs showed that DHT inhibited the growth of ORS cells. L-Threonate significantly reversed this phenomenon. Collectively, these results suggest that L-Threonate inhibits DKK-1 expression in DPCs and, thus, is a promising therapy for the prevention of androgen-driven alopecia.

Such emerging research suggests it could be significant. Some studies indicate that a magnesium deficiency could contribute to hair loss. Magnesium forms hair follicles, the tiny sacs in the skin where hair growth begins. Without enough magnesium, the hair follicles may not function properly, leading to hair loss.

In addition, magnesium may support to reduce inflammation, which has been linked to hair loss. According to certain studies, there is evidence to suggest that inflammation occurring in the scalp has the potential to impair hair follicles and impede the process of hair growth. By reducing inflammation, magnesium could help protect the hair follicles and promote healthy hair growth.

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Magnesium L-Threonate Formulation References

Regarding hair health, a multi-faceted approach often yields the best results. Magnesium L-Threonate, unique ability to cross the blood-brain barrier and contribute to various physiological processes, is a promising supplement ingredient for hair health. However, its potential can be further amplified with other proven hair-loss ingredients. 

  • Vitamin B7 Biotin
  • Saw Palmetto Extract:
  • Vitamin D
  • Omega-3 Fatty Acids
  • ETC.

The ingredients mentioned above are all good for hair loss. For example, Biotin is a commonly acknowledged nutritional supplement ingredient believed to have beneficial effects on nails, hair, and skin health. Saw Palmetto is a plant known for its health benefits. It has the potential to inhibit the enzymatic activity responsible for the conversion of testosterone to DHT, a hormone associated with the occurrence of alopecia. Vitamin D is essential for creating new hair follicles and promoting growth. Omega-3 fatty acids display anti-inflammatory qualities that may have the capacity to improve the condition of the scalp and stimulate hair growth.

Magnesium L-Threonate Reviews: What Do The Experts Say?

The potential benefits of Magnesium L-Threonate for hair health have sparked interest among several experts and professional bodies. For instance, the American Hair Loss Association emphasizes the significance of a balanced diet for hair health, including sufficient consumption of vital nutrients such as magnesium.

The National Institutes of Health also acknowledges that while further research is required, magnesium might have a role to play in hair health. They highlight that magnesium participates in several vital processes crucial for hair growth, such as protein synthesis and the creation of new hair follicles.

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In Conclusion: The Potential Of Magnesium L-Threonate For Hair Health

Research on the potential benefits of Magnesium L-Threonate for hair health is still in its early stages, but the current evidence is promising. This form of magnesium uniquely can cross the blood-brain barrier, directly impacting the brain and nervous system, which can have wide-ranging effects on overall health.

Magnesium L-Threonate regulates hormonal balance, which is crucial for various aspects of health, including hair growth. Imbalances in hormones like DHT can lead to hair loss, and by helping to regulate hormonal balance, it may prevent hair loss and promote healthy hair growth.

Another benefit is its role in reducing inflammation. Chronic inflammation has been linked to hair loss and other health issues. By reducing inflammation, Magnesium L-Threonate can create a healthier environment for hair follicles, promoting hair growth and preventing hair loss.

Furthermore, Magnesium L-Threonate is involved in protein synthesis, including the synthesis of keratin, an essential structural component of hair. It can provide the necessary building blocks for hair growth by supporting protein synthesis.

Although more research is needed to fully understand the extent of Magnesium L-Threonate’s benefits for hair health, the existing evidence suggests it could be a valuable tool for addressing hair loss. Its unique properties and involvement in critical physiological processes make it a promising option for supporting hair health.

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