How To Manufacture Creatine Monohydrate Powder?

manufacturing creatine monohydrate powder

Creatine is a compound that enhances the contraction of muscle fibers. It can effectively improve muscle strength, endurance, speed, and size. Therefore, creatine monohydrate powder has become an important supplement for athletes and fitness enthusiasts.

As the creatine market grows, its production process has continuously improved and upgraded. There are two common creatine powder production processes. One is protein extraction. One is synthesis. This article will introduce these two production processes and their main production processes.

Creatine Powder Is Derived From Protein.

The production of creatine requires protein extraction. Protein sources are generally poultry, raw, pig, fish, and other animal muscle tissues. Plant proteins can also be used as raw materials.

Protein extraction requires a series of processes such as alkaline hydrolysis, acid hydrolysis, hydrolysis, and enzymatic hydrolysis to finally obtain the protein liquid. The protein liquid is then processed through filtration, decolorization, etc., to remove impurities.

Two Major Reactions In Creatine Synthesis

Creatine synthesis requires two main reactions, including creatine acidification reaction and creatine shrinkage acidification reaction.

Creatine acidification reaction converts creatine in protein liquid into creatine through a chemical reaction. This process requires using chemical reagents such as dilute sulfuric acid and sodium hydroxide, as well as high-temperature and high-pressure conditions. The creatine produced by the reaction is often incompletely hydrolyzed and requires subsequent processing.

The creatine acidification reaction requires reagents such as sodium creatine, phosphoric acid, and sodium hydroxide. Creatine and ornithine are produced in the early stages of the reaction. Subsequently, dimethylhydroxyacetone phosphate (DHAP) and acetylacetonate phosphate (AcP) is produced. Finally, creatine and creatinine can be generated by migrating acyl groups.

After a complex reaction process, the product may contain a variety of impurities. It requires refining. Refining treatment usually includes acid and alkali neutralization, filtration, decolorization, crystallization, drying, and other processes. Among them, crystallization is the key to the refining process. It enables control of the final purity and particle size of the product. Generally speaking, the most recognized specification on the market is Creatine Monohydrate powder 80/200 mesh.

Synthetic Creatine Monohydrate Powder

Generally speaking, the raw material of synthetic creatine is mainly chloroacetic acid. The creatine solution is obtained by reacting the methylamine solution with the chloroacetic acid solution. It is then dilute-filtered. After washing and drying, crude creatine monohydrate can be obtained. After the final recrystallization, high-quality, high-purity creatine monohydrate can be obtained.

Compared with the protein extraction process, the cost of creatine powder under the synthetic process is lower.

How Is Creatine Packaged And Stored?

Generally speaking, creatine powder is usually packaged in aluminum foil bags and plastic barrels. Storage conditions generally require sealing, dryness, protection from light, and low temperature (not exceeding 25°C).

Creatine Powder Near Me

Recently, chloroacetic acid, the raw material of creatine monohydrate, has been in a shortage. It has resulted in the creatine market being in short supply. Its market price has also increased exponentially. Many factories have stopped quoting prices. If there are still orders, it will basically need to wait until 2024 for delivery. Nutri Avenue also offers creatine monohydrate powder. Inventories are tight. Please contact our sales team to obtain the latest creatine price if necessary.

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