Meclofenamate Sodium is a non-steroidal anti-inflammatory drug used in the treatment of various inflammatory conditions including arthritis and dental pain. It is also used widely in the prevention and treatment of menstrual cramps, as well as other forms of muscle cramping. The compound may also be used for the treatment of vertigo.
What is Meclofenamate Sodium?
The compound Meclofenamate Sodium is the sodium salt of Meclofenamate. It belongs to the fenamate class of NSAIDs and is considered a cyclooxygenase (COX) inhibitor. The use of the compound as a drug for mild to moderate pain brought about by several associated conditions has become widespread over the years since it was approved for use by the Food and Drug Administration in the 1980s. Aside from its use in human pharmacology, the compound is also beneficial in the treatment of chronic musculoskeletal disease and other inflammatory conditions in horses and other animals. The compound is also shown to help reduce blood loss from menstrual periods.
Meclofenamate Sodium is also known as Meclofenamic acid, Sodium Meclofenamate, and Meclofenamic acid sodium salt. It is also popular for its brand name Meclomen. The CAS number of the compound is 644-62-2. Its molecular formula is C14H11Cl2NO2 and its molecular weight is 296.15 g/mol.
The compound is described as having a white to creamy white crystalline powder appearance. It is generally odorless and is soluble in organic solvents like DMSO, ethanol, and dimethylformamide. Without its sodium salt component, Meclofenamate sodium is poorly soluble in aqueous solutions.
Meclofenamate Sodium forms and specifications
For pharmaceutical product formulations, Meclofenamate Sodium is commonly used in powder forms with 99% purity assays. Meclofenamate Sodium powder 99% is available at various ingredient supplier stores online.
When bought in bulk at Nutriavenue, the product is usually packed in paper drums with two layers of poly bags inside. Each drum contains about 25 kilograms of the compound. Packaging may vary depending on the customer’s preference and the number of products to be purchased.
Meclofenamate vs Diclofenac
Diclofenac is another non-steroidal anti-inflammatory drug used in the treatment of several inflammatory conditions. Just like Meclofenamate, Diclofenac is a powerful painkiller, especially when used for menstrual pain relief.
While there are no distinctive differences between the said compounds, they generally vary in terms of general classifications. Meclofenamate is classified mainly as an anti-inflammatory compound. In contrast, Diclofenac is categorized as an antipyretic drug and a non-narcotic analgesic. Also, while Meclofenamate is a balanced Cox 1/Cox2 inhibitor, Diclofenac is a selective Cox 1/Cox 2 inhibitor.
Meclofenamate and Metformin
Metformin is a common drug used to control blood sugar levels among diabetic patients. Studies reveal that the use of Meclofenamate along with Metformin may cause lactic acidosis or the accumulation of lactic acid in the blood. This can be potentially life-threatening and may bring about long-term and short-term effects such as unstable congestive heart failure and liver damage.
Due to the potential interaction between Meclofenamate and Metformin, the use of the drug in combination should be prevented.
Meclofenamate Sodium and Naproxen Sodium
Naproxen Sodium is another non-steroidal anti-inflammatory drug used in joint stiffness, muscle aches, and menstrual cramps. Due to risks of bleeding and other accompanying adverse effects, Meclofenamate Sodium should not be used along with Naproxen Sodium. This is because the combination of the compounds may lead to unlikely drug interactions.
How does Meclofenamate Sodium work?
Meclofenamate Sodium works primarily as a cyclooxygenase (COX) inhibitor. By inhibiting the activity of these enzymes, it is believed that the compound effectively prevents the formation of prostaglandins and thromboxanes.
Prostaglandins are natural bodily enzymes that are produced during acute trauma or infection. The increase in prostaglandins results in pain and inflammation. Meclofenamate Sodium helps reduce pain and inflammation during infection and inflammation by acting as a prostaglandin synthase.
The compound also helps reduce blood clotting by preventing the formation of thromboxanes.
What is Meclofenamate used for?
The following are among the most well-known benefits of using Meclofenamate:
It may be used for muscular pain
Muscular pain brought about by inflammatory conditions such as arthritis may be controlled with the intake of Meclofenamate Sodium. The compound may also help reduce menstrual pains brought about by irregularities in hormone production. This is because Meclofenamate Sodium works as a Cox1/Cox 2 inhibitor which, in effect, helps reduce pain sensation.
It may be used for cramps
Mild to moderate cramps brought about by muscle contraction may also be controlled with Meclofenamate Sodium intake. However, since the compound is usually taken orally, the effects of pain reduction for cramping may take time and are not immediate.
It may work against vertigo
Vertigo can be caused by various factors including underlying disorders. If the condition is caused by a stroke or brain trauma, it may be controlled with the intake of non-steroidal drugs like Meclofenamate Sodium. However, if the condition is caused by factors including infection or blood vessel constriction, Meclofenamate Sodium may not be used to treat it.
Meclofenamate Sodium side effects
Meclofenamate Sodium should not be taken for long periods unless with a physician’s recommendation. Some of the common side effects of using Meclofenamate Sodium include headaches, nausea, diarrhea, and other mild gastrointestinal symptoms. However, short-term use of the compound within recommended doses does not necessarily cause side effects, especially among healthy adults.
Meclofenamate Sodium dosage
Most physicians recommend the intake of Meclofenamate Sodium for pain relief at 100 mg, taken three times a day. However, the said recommended dosage may vary depending on the individual user’s age, weight, and overall physical condition.
Pregnant and lactating women are advised to consult their physicians before using the compound for any purpose.
Where to buy bulk Meclofenamate Sodium powder?
Meclofenamate Sodium powder may be purchased in bulk or lesser quantities from Nutriavenue. Our company is duly registered as an ingredient supplier with the Food and Drug Administration. We are also recognized and certified by regulatory entities like Kosher, GMP, and Halal.
Aside from Meclofenamate Sodium, we also offer many other compounds and ingredients which may be useful for pharmaceutical product formulations and other purposes. We are among the best suppliers as we offer high-quality products at very affordable prices.
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