Naringin: An Antioxidant Flavonoid Against Cellular Aging

Naringin helps maintain healthy blood pressure

Naringin is a naturally occurring flavonoid compound known for its various pharmacological actions. It is believed to help reduce oxidative stress in body cells, thereby preventing rapid aging and degeneration. It is also known to have anti-inflammatory and antioxidant properties.

What is Naringin?

Naringin is supplement ingredient classified as a flavanone-7-O-glycoside between naringenin and the disaccharide neohesperidose. It is a disaccharide derivate isolated primarily from grapefruit and other citrus fruits. Essentially, the compound Naringin is responsible for the bitter taste of its plant sources. However, when metabolized in the human body through naringinase which is present in the gut, its bitter taste disappears. As a metabolite, Naringin is believed to possess antineoplastic and antihypertensive properties, among other health benefits.

Other names for the compound include Naringetol, Salipurol, Salipurpol, (2S)-4′,5,7-Trihydroxyflavan-4-one, and grapefruit extract. It is identified as having CAS number 10236-47-2. Its molecular formula is C27H32O14 and its molecular weight is 580.54 g/mol.

In dietary supplement formulations, Naringin has a yellow to whitish powder appearance. While the compound is soluble in water, its solubility in aqueous solutions is said to be poor. Nonetheless, the inclusion of cyclic oligosaccharides in the compound may improve water solubility.

Naringin sources and bioavailability

Naringin is typically derived from grapefruit peel extract or Citrus paradisi. Although the term “naringin” is said to be derived from the term “narangi” which refers to the citrus fruit “oranges”, experts say that Grapefruit contains the highest concentrations of Naringin. The compound may also be found in tomatoes, oregano, and cherries.

Being in the glycosidic form, the compound is known to have lesser bioavailability than the aglycol form Naringenin.

Naringin forms and specifications

Naringin is included in dietary supplement formulations in powder forms with 98 to 99% purity assays. Pure Naringin powder is available among suppliers of dietary supplement products online. When making a purchase, it is important to choose only the best legitimate ingredient suppliers like Nutriavenue.

Depending on the quantity of your purchase, the compound may be packed in paper drums with two layers of poly bags inside. Each drum typically contains a net weight of 25 kilograms. You may also purchase lesser quantities and request changes to the product packaging.

Citrus Bioflavonoids

Citrus bioflavonoids are known for their powerful antioxidant properties. They may be isolated from various parts of citrus plants such as the roots, stem, or fruits. Among the most popular citrus bioflavonoids are Naringin, Narirutin, Neohesperidin, Nobiletin, Rutin, and Tangeretin.

Naringenin to Naringin

Naringenin is the predominant flavone in grapefruit extract. The inclusion of disaccharide neohesperidose in the skeleton structure of the aglycone flavonoid Naringenin results in the production of Naringin. Naringin is believed to have a lesser potential pharmacologic effect due to the interaction of stearic hindrance in the scavenging group of the compound.

Kaempferol and Naringin

Kaempferol is another bioflavonoid compound isolated from grapefruit and other citrus fruits. They are also found to exist in the Chinese medicinal product Drynariae rhizome. Both compounds are known to possess antioxidant properties. It is also suggested that these compounds may be useful in the prevention of osteoporosis and other bone-related health conditions.

Vitamin C and Naringin

Vitamin C and Naringin are currently being combined for their potential antihyperglycemic effects among Type II Diabetes Mellitus patients. It is believed that the combination of the compounds creates a synergistic effect not only in diabetes control but also in providing antioxidant benefits.

How does Naringin work?

Naringin is believed to help improve health and wellness by acting as a modulator to various bodily processes. It is said that the compound modulates certain signaling pathways in the body. It also reduces oxidative stress and promotes detoxification of body cells to prevent rapid wear and tear brought about by circulating free radicals.

Naringin benefits

Naringin in dietary supplement formulations may provide various health benefits which include the following:

It provides antioxidant benefits

As an antioxidant compound, Naringin is known to help prevent the hasty progression of various cancer types. It may also prevent the rapid development of signs of aging among individual users. The use of Naringin along with Vitamin C is also said to result in an enhanced antioxidant effect.

It prevents cellular aging

Oxidative stress is one of the factors that hasten cell death. According to researches, Naringin may help prevent cellular aging by reducing oxidative stress. These are among the benefits of using Naringin as an antioxidant compound.

It supports cardiovascular health

Many studies suggest that Naringin supplementation may effectively protect the heart from myocardial infarction and hypertrophy. It may also prevent various cardiac anomalies by acting as a modulator to signaling pathways.

It helps maintain good cholesterol levels

Having normal levels of High-density lipoproteins (HDLs) or good cholesterol help improve wellness by preventing the development of various metabolic disorders. Experts say that Naringin supplementation may help maintain good cholesterol levels.

It helps maintain healthy blood pressure

Naringin is also a well-known antihypertensive compound. The compound works relaxing muscles covering blood vessels, thereby promoting dilation of same. Improved blood pressure results in healthy circulation of oxygen and nutrients in the various vital organs of the body.

Naringin side effects

Taking Naringin dietary supplements is not necessarily associated with serious side effects. Nonetheless, some of the notable mild side effects associated with the use of the compound include nausea, stomach ache, and stomach irritation. If serious adverse effects occur, health practitioners suggest users immediately consult a physician.

Naringin dosage

There is no fixed recommended dose for Naringin supplementation. However, most physicians suggest that a dose of 40 to 80 mg/kg body weight may be beneficial among individual users. The recommended dose may vary depending on the age, weight, and overall physical condition of the individual user. It may also vary depending on what is the intended purpose of supplementation is

Where to buy bulk Naringin powder?

Naringin powder in bulk or lesser quantities can be purchased from Nutriavenue, an FDA-registered ingredient supplier recognized and certified by Halal, Kosher, and GMP. When it comes to high-quality and affordable ingredients, our company is the best choice.

Aside from Naringin powder, we also offer shipping services through air, sea, and couriers like FedEx and UPS.

For more information on our products and the services we offer, you may visit our website or you may contact our technical support staff. You may also avail of a free quote when you visit our website.

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