Phophatidylserine: Sustainer of the Brain’s Cellular Function


Phophatidylserine: Sustainer of the Brain’s Cellular Function

Optimum brain function is brought about by the interaction of neurotransmitters, nerve cells and essential brain enzymes. While most nootropics work on neurotransmitters and nerve cell protection, some effective ones primarily act upon essential enzymes, thus maintaining optimum mental health. A classic example of a phospholipid nootropic which helps improve cognitive function by maintaining the brain’s cellular function is Phosphatidylserine. The compound Phosphatidylserine is readily found in several food sources such as cabbage and soybeans but due to their limited contents in food and their degeneration during chemical digestion, supplementation of the drug in specific dosages through nootropic health supplements is more advisable.

What is Phosphatidylserine?

Otherwise known as Bovine Cortex Phosphatidylserine or PtdSe, the compound Phosphatidylserine was originally derived from cow’s brains. With the rising issues on health risks due to their sources, however, experts have shifted sources to common fruits and vegetables containing Phosphatidylserine. The compound is naturally-occurring in the body and is primarily responsible for various nerve cell functions including perception and stimulus interpretation. With massive neuron degeneration secondary to aging, however, the amount of Phosphatidylserine reduces, leading to decline in overall mental function. The effects of naturally-derived Phosphatidylserine in the body have long been established to be as effective as the naturally-occurring ones. Since the derivative sources are also natural in form, many experts say that the inclusion of Phosphatidylserine in nootropic supplement formulations is best for individual users.

What are the benefits of using Phosphatidylserine?

Adequate Phosphatidylserine levels among elderly individuals can lead to a lot of health benefits. The following are the benefits of using the compound:

  1. It can prevent age-related cognitive disorders

Age-related cognitive disorders like Alzheimer’s disease and Dementia remain to be untreatable due to their rapid effects on the patients after diagnosis. While some experts believe that the development of the disorder is brought about by neurotransmitter decline and neuron damage, some theories provide that the reduction of naturally-occurring Phosphatidylserine can lead to the conditions. Supplementation of the enzyme through Phosphatidylserine-containing health supplements can help prevent age-related cognitive disorders and their rapid progression.

  1. It may reduce ADHD symptoms

ADHD or Attention Deficit Hyperactive Disorder is a common mental condition affecting children. Although the exact cause of the disorder is still unknown, experts believe that ineffective use of the compound Phosphatidylserine can predispose children to the condition. Phosphatidylserine nootropics help regulate the uptake and use of the compound for better brain function and the reduction of ADHD symptoms.

  1. It may contribute to inflammation control

Inflammation control works through the integration of the immune system and the nervous system. There are only a few studies conducted on finding the relation between inflammation and Phosphatidylserine supplementation but most studies say that the compound may help prevent inflammation and muscle soreness after strenuous exercises.


Although Phosphatidylserine supplementation has long been associated with mild side effects like gastrointestinal upset, physicians say that these side effects are considered normal during the first few doses. Phosphatidylserine is one of the best ways to prevent Alzheimer’s disease and protect the elderly from stressful cognitive dysfunction symptoms.

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