On April 27, foreign media reported that PLT Health Solutions is launching a new ingredient that supports immune health. This ingredient is called the Spectramune Immune Defense Complex (or “Spectramune”), a synergistic combination of Withania Somnifera and Terminalia chebula.
What Is Spectramune Immune Defense Complex?
Spectramune powder has a mild taste, 70%-80% water solubility, and is suitable for various dosage forms, including tablets, capsules, soft capsules, functional foods and beverages, and various immune formulas.
Seth Flowerman, president and CEO of PLT Health Solutions, said that while the immune health support category has grown dramatically over the past few years, many ingredient solutions on the market have been around for decades, if not longer. This new ingredient was developed to address industry and consumer demand for novel immune health support solutions.
According to Flowerman, the goal of developing the Spectramune process with innovative partner Laila Nutraceuticals (a health supplement company) was to create a new approach to immune health support. The selection of plants with immunomodulatory potential was narrowed down to 40 through an advanced screening process, and the optimal formulation was identified through systematic testing of potential combinations.
And he mentions: “The clinical work done to support Spectramune demonstrates an advanced ingredient capable of bringing something new and exciting to the field of immune health. Formulators of immune health products can use Specramune as a base ingredient Or in combination with existing formulations to meet a wide range of immune healthcare needs of consumers.”
Did Spectramune Have Any Clinical Studies?
Data from clinical studies of immune biomarkers showed significant improvement in targeting innate, cell-mediated, and humoral immunity across a wide range of immune cells. These markers are associated with the first line of immune defense (innate), supporting the body’s slower immune response to unfamiliar pathogens (cell-mediated) and memory/antibodies to exposure to new pathogens and vaccinations (humoral) reaction.
In order to confirm whether Specramune can achieve the expected effect, a series of clinical studies are needed to confirm.
PLT also conducts clinical research.
In a four-week randomized, double-blind, placebo-controlled trial, male and female subjects (35-60 years) considered themselves immunocompromised and consumed 500 mg of Spectramune per day compared to placebo.
- Humoral immunity
Spectramune affects key markers of humoral immunity. Supplementation significantly increased serum IgG levels compared with placebo, suggesting a humoral immune response.
- Cell-mediated immunity
Spectramune also affected key markers of cell-mediated immunity, including total T cell population, CD4+ T cells, and CD4+/CD8+ ratio. Supplementation with Spectramune significantly increased total T cells and CD4+ T cells (compared to baseline and placebo). In addition, the CD4+/CD8+ balance was significantly improved (compared to baseline and placebo).
- Innate immune factors and immune function
Spectramune increases IFN-γ and improves perceived immune function. Spectramune supplementation significantly increased serum IFN-γ levels compared with placebo. NK cells increased significantly compared to the control group but not significantly compared to the placebo group. Perceived immune status improved from baseline in both groups, but at day 28, the improvement was significantly greater in the Spectramune group than in the placebo group.
Jennifer Murphy, director of innovation and clinical development at PLT, said the study’s findings provide some support for immune health product developers. Many immune ingredients on the market, including those derived from fungi, such as polysaccharides or other fibers, support the immune system similarly.
Besides this new ingredient, many other ingredients, such as Vitamin C, Vitamin B 6, Vitamin E, Zinc ingredients, etc., support the immune system. And these raw ingredients are available from Nutri Avenue.
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