PQQ Powder: How To Use It In Different Products?


Currently, the common PQQ supplement products on the market are mainly aimed at brain health, sleep aids, energy supplements, oral beauty, and fertility assistance. PQQ powder is often used with various raw materials such as coenzyme Q10, GABA (Γ-aminobutyric acid), Ginkgo leaf extract, phosphatidylserine (PS), etc.

PQQ And COQ10 For Heart Health

Both PQQ and CoQ10 are involved in mitochondrial energy production. The two can be used together to achieve better results. This combination is the most common among PQQ-related supplements currently on the market. It is primarily used in heart health, energy, and brain-boosting supplements.

PQQ And Phosphatidylserine Powder, Targeting Brain Health

Over time, the mitochondria of nerve cells in the nervous system and brain degrade. In addition to impairing memory and attention, mitochondrial degradation has been linked to diseases such as Alzheimer’s and Parkinson’s. PQQ is supplemented with nootropic ingredients such as Phosphatidylserine PS, which prevents mitochondrial degradation, supports better brain performance, and enhances memory.

PQQ Powder And GABA Powder For Sleep Health

PQQ can relieve sleep disorders caused by anxiety by reducing the stress hormone cortisol. It effectively reduces the time it takes to fall asleep and improves sleep quality. It can be used in combination with GABA and other sleep aid ingredients.


  1. PQQ Powder can also be used with kudzu root, turmeric, probiotics, etc., to relieve hangovers.
  2. Pyrroloquinoline quinone disodium salt is used with vitamin C, zinc, vitamin D, etc., to enhance the body’s immunity.

PQQ Pyrroloquinoline Quinone: What Are Its future application directions?

With the continuous deepening of knowledge, PQQ Powder has achieved the most comprehensive efficacy certification in recent years. It is widely used as a dietary supplement or food in many countries and regions worldwide. Judging from PQQ’s current application market distribution, it is more concentrated in overseas markets and is often used in energy, sports, electrolytes, nutritional supplements, etc.

PQQ powder has been recognized as a new raw ingredient for its positive effects on nutrition and health. Due to its powerful functions, high safety, and good stability, it has broad development prospects in functional foods.

How To Manufacture PQQ Powder?

PQQ powder has two production processes, including synthesis and microbial fermentation.

  • Synthesis

Pyrroloquinone quinone disodium salt is made from 6-amino-5-methoxy-1H-benzoic acid ethyl ester and 2-oxoprenedioic acid dimethyl ester. The two raw materials are made through coupling ring-forming reaction, formation of ring, oxidation reaction, ester hydrolysis reaction, and refining.

  • Microbial fermentation synthesis

Methylovorus Glucosotrophus is used as the fermentation strain and is made through fermentation, extraction, purification, crystallization, drying, and other processes.

Currently, PQQ powder based on microbial fermentation synthesis method is more recommended on the market. Its quality is better, and its purity is higher.


Nutri Avenue discovered this high-quality ingredient early and registered its own trademark product – NUTRIPQQ®. There are already many PQQ supplements that use NUTRIPQQ® as their main ingredient. Feel free to contact our sales team for more information.

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