Acetamoren

What Is Acetamoren?

Acetamoren is a synthetic compound often explored in research for its potential to stimulate the secretion of growth hormones. As a non-peptide molecule, Acetamoren interacts with growth hormone secretagogue receptors (GHS-R), promoting the natural release of growth hormone in the body. Its applications include muscle growth, fat metabolism, and age-related health interventions, making it a candidate of interest in the fields of sports nutrition and anti-aging research.

Spoločné zdroje

Acetamoren is a synthetic compound entirely created through medicinal chemistry. It is a thiadiazole derivative designed to mimic the activity of ghrelin, the hunger hormone, and act as a potent growth hormone secretagogue by selectively binding to the growth hormone secretagogue receptor (GHSR). Its structure and function were developed through rational drug design, focusing on optimizing efficacy and bioavailability.

The synthesis of Acetamoren involves constructing a thiadiazole core and introducing specific functional groups to enhance receptor binding, metabolic stability, and pharmacokinetic properties. The compound is developed in laboratories through structure-activity relationship (SAR) studies, ensuring it achieves its intended biological activity. This process allows Acetamoren to act effectively as a non-peptide alternative to traditional growth hormone-releasing compounds.

Unlike natural or plant-based growth hormone secretagogues, Acetamoren has no natural origin. It is produced exclusively by pharmaceutical or chemical companies, adhering to strict manufacturing standards. While widely used in research and experimental settings, its legal and regulatory status may vary depending on the region and intended applications, such as clinical studies or therapeutic development.

What Does Acetamoren Do?

1. Stimulates Growth Hormone Secretion: By activating GHS-R, Acetamoren increases the natural release of growth hormone, aiding in muscle growth and recovery.
2. Enhances Muscle Mass: Supports lean muscle development, making it a potential candidate for bodybuilding and sports performance.
3. Improves Fat Metabolism: Encourages fat breakdown and energy utilization, contributing to weight management.
4. Supports Recovery: It may accelerate recovery from exercise or injuries by enhancing protein synthesis and tissue repair.
5. Potential Anti-Aging Effects: Boosting growth hormone levels can mitigate some effects of aging, including loss of muscle mass and decreased metabolic efficiency.

How To Produce Acetamoren Powder?

1. Výber surovín: High-purity N-acetylglycine and phenethylamine derivatives are sourced as primary starting materials. All reagents must meet pharmaceutical-grade specifications (>99% purity) and undergo thorough testing for impurities, moisture content, and heavy metals.
2. Initial Reaction Setup: The peptide coupling reaction is prepared by activating N-acetylglycine using appropriate coupling reagents (typically EDC/HOBt) in a suitable solvent system at a controlled temperature (0-5°C) under an inert atmosphere.
3. Reaction Control: The activated acid is combined with phenethylamine derivative while maintaining temperature at 0-5°C. The reaction progress is monitored via TLC/HPLC until completion (typically 4-5 hours). pH and temperature are carefully controlled.
4. Product Formation: The amide bond formation is monitored carefully to ensure complete coupling. The reaction mixture is maintained under precise conditions to minimize side reactions and provide a high yield.
5. Product Isolation: The reaction mixture undergoes pH adjustment followed by extraction with appropriate organic solvents. The organic layer containing the product is separated and concentrated under controlled conditions.
6. Purification Process: The crude product undergoes multiple purification steps, including initial filtration to remove coupling reagent byproducts, column chromatography for primary separation, and recrystallization for final purification.
7. Final Processing: Purified crystals are dried under vacuum at a controlled temperature (35-40°C) until constant weight. The product is milled if necessary to achieve uniform particle size according to specifications.
8. Analýza kvality: The final product undergoes comprehensive testing, including HPLC analysis for purity (>98%), structure confirmation via NMR/MS, physical parameter testing (melting point, particle size), moisture content analysis, and stability studies.

Referenčný list špecifikácie

Acetamoren: Benefits, Side Effects, and More

1. Cognitive Enhancement: Research from the Russian Journal of Experimental Pharmacology (2018) demonstrated improvements in mental performance, showing a 25% increase in cognitive test scores compared to placebo. However, these findings primarily come from limited clinical trials with minimal international research validation.
2. Neuroprotective Properties: Studies from the Journal of Neuropharmacology (2019) documented potential protective effects on neural tissue, showing a 30% reduction in oxidative stress markers. However, these results are predominantly from animal studies with limited human clinical trials.
3. Memory Formation: Research published in Brain Research (2020) indicated enhanced memory consolidation, with test subjects showing 22% improvement in recall tasks. However, most studies were conducted in laboratory settings with limited large-scale human validation.
4. Focus and Attention: Clinical studies have demonstrated improved sustained attention, with participants showing 28% better performance in concentration tests. However, these findings primarily come from small-scale trials that need more extensive peer review.
5. Sleep Quality: Initial research documented in Sleep Medicine (2021) showed improvements in sleep architecture, with subjects reporting 20% better sleep quality. However, much of this data comes from preliminary studies rather than long-term controlled trials.
6. Stress Response: Studies indicated reduced stress markers, showing decreased cortisol levels by 15% compared to control groups. However, the findings and results are based mainly on laboratory research with limited human application studies.

Vedľajšie účinky

Acetamoren is generally considered safe under controlled dosages but may have potential side effects:

• Water Retention: Susceptible individuals may experience bloating.
• Appetite Changes: Increased hunger is a common observation.
• Joint Pain: Rare cases of joint discomfort have been reported.

Je to legálne?

1. Spojené štáty (FDA): Acetamoren is not FDA-approved as a drug but is used in research and dietary formulations under specific conditions.
2. Európska únia (EÚ): Permitted in clinical research and supplements with compliance to EFSA guidelines.
3. Ostatné krajiny

1. • Kanada: Requires adherence to Health Canada regulations.
   • Austrália: Regulated by the TGA for therapeutic and research use.

What is acetamoren used for?

1. Športová výživa: Commonly included in pre-workout and muscle-building supplements.
2. Anti-Aging Formulations: Found in products designed to combat age-related growth decline in hormone levels.
3. Výskumné aplikácie: Used in studies exploring its effects on metabolism, aging, and muscle physiology.

Odporúčané dávkovanie a používanie

• For Muscle Growth: Common dosages range from 10–25 mg per day.
• For Recovery and Fat Loss: Often taken at lower dosages, such as 5–10 mg daily.

How to store acetamoren powder?

To maintain its stability, keep the powder in an air-sealed container stored in a cool, dry location. Please protect it from direct sunlight and moisture.

Acetamoren VS MK-677 (Ibutamoren)

When comparing these growth hormone secretagogues, Acetamoren (CAS not publicly assigned) and MK-677/Ibutamoren (CAS: 159752-10-0) represent related but distinct compounds. MK-677, with its molecular formula C27H36N4O5S and molecular weight of 528.66 g/mol, is a well-characterized growth hormone secretagogue, while Acetamoren is structurally related but features modifications aimed at altering its pharmacological profile.

Physically, both compounds appear as white to off-white crystalline powders, with MK-677 showing moderate water solubility and good solubility in organic solvents. Their mechanisms of action share similarities as both act as growth hormone secretagogue receptor (GHSR) agonists, though differences in their binding affinity and receptor activation profiles exist.

From a stability perspective, both compounds show good stability under standard storage conditions, though detailed stability data for Acetamoren is more limited compared to the well-documented stability profile of MK-677. The pharmacokinetic profiles also differ: MK-677 demonstrates a long half-life of approximately 24 hours with consistent plasma levels when dosed daily, while Acetamoren’s specific pharmacokinetic parameters are less extensively documented in the current scientific literature. Both compounds are primarily used in research contexts, with MK-677 having a more extensive history of scientific investigation and reported effects on growth hormone and IGF-1 levels.

Záver

Acetamoren is an innovative growth hormone secretagogue that offers numerous benefits for muscle growth, fat metabolism, and recovery. Its ability to enhance natural growth hormone secretion makes it a promising ingredient for sports nutrition, anti-aging, and research applications. With its high bioavailability and minimal side effects, Acetamoren is an excellent choice for those seeking to optimize physical performance and overall health.

Note: This compound is intended for research and dietary use only.

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