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What Is Sodium Copper Chlorophyllin?
Sodium Copper Chlorophyllin is a water-soluble derivative of chlorophyll, known for its powerful antioxidant, detoxifying, and deodorizing properties, with the CAS number 11006-34-1, a molecular formula of C34H31CuN4Na3O6, and a molecular weight of approximately 724.14 g/mol.
Unlike natural chlorophyll, which is fat-soluble, it is chemically modified for enhanced stability and absorption, making it widely used in dietary supplements, food colorants, and personal care products. Derived from sources like alfalfa, spinach, and mulberry leaves, it is known for promoting liver detoxification, gut health, and immune function while helping to neutralize odors in the body. It typically appears as a dark green to bluish-green fine powder.
It is highly water-soluble and often formulated into capsules, tablets, and liquid supplements. Marketed as powder, it is packaged in airtight, moisture-resistant containers to maintain stability, making it a key ingredient in cleansing, anti-inflammatory, and overall wellness formulations.
Spoločné zdroje
1. Chemical Sources
- Synthetic Chlorophyll – Chemically synthesized chlorophyll undergoes saponification to produce Sodium Copper Chlorophyllin.
- Copper Salts – Copper salts (such as copper sulfate) replace the magnesium ion in chlorophyll, forming a more stable copper-chlorophyllin complex.
- Alkaline Reagents – Substances like sodium hydroxide (NaOH) are used in the saponification process to modify the chlorophyll structure and improve water solubility.
2. Plant-Based Sources
SCC can also be extracted from chlorophyll-rich plants, including:
- Mulberry leaves
- Alfalfa
- Spinach
- Wheatgrass
- Fava bean leaves
In plant extraction, natural chlorophyll is first isolated from these plants. It then undergoes a saponification process to remove the fat-soluble components. Finally, magnesium ions are replaced with copper ions to enhance water solubility, resulting in Sodium Copper Chlorophyllin.
Compared to chemical synthesis, plant-based SCC is often preferred for natural health products and is commonly used in food additives, dietary supplements, and cosmetics.
What Does Sodium Copper Chlorophyllin Do?
One of its primary mechanisms of action is its antioxidant activity. What is sodium copper chlorophyllin‘s role in this context? The compound can neutralize free radicals and reactive oxygen species (ROS), protecting cellular components from oxidative damage. This antioxidant activity is attributed to the copper-chlorin complex at the molecule’s center. Additionally, it has been shown to enhance the activity of endogenous antioxidant systems, such as superoxide dismutase and glutathione peroxidase. This dual action of direct scavenging and enhancement of endogenous antioxidant systems contributes to the compound’s potential in combating oxidative stress.
It also can bind to and form molecular complexes with various mutagens and carcinogens. This binding can occur in the gastrointestinal tract, potentially reducing the absorption and bioavailability of these harmful substances. Research has shown that sodium copper chlorophyllin powder can form tight molecular complexes with polycyclic aromatic hydrocarbons and heterocyclic amines, known carcinogens in cooked meats and other food sources. By creating these complexes, the compound may help reduce the exposure of tissues to these potentially harmful substances.
It also exhibits anti-inflammatory properties through multiple pathways. It has been shown to inhibit the activity of cyclooxygenase (COX) enzymes, which produce pro-inflammatory prostaglandins. Furthermore, this chlorophyllin derivative has been observed to modulate the expression of inflammatory cytokines and reduce the activation of NF-κB, a key transcription factor in inflammatory responses. These anti-inflammatory actions contribute to the potential of this compound in addressing inflammation-related conditions.
How to Produce Sodium Copper Chlorophyllin Powder?
- Initial Material Selection: This ingredient’s production begins with the careful selection of chlorophyll-rich plant sources, such as mulberry leaves, alfalfa, or spinach. These botanical raw materials undergo stringent quality testing to verify chlorophyll content, heavy metal levels, and microbial safety. The leaves are thoroughly cleaned and processed to remove unwanted contaminants before extraction. Ensuring high chlorophyll purity in the raw materials is crucial to achieving optimal yield and stability in sodium copper chlorophyllin powder production.
- Proces extrakcie: The first step in isolating the compound involves solvent extraction using food-grade ethanol or acetone under controlled conditions (40-60°C). The extracted chlorophyll is then subjected to saponification using a mild alkaline solution, typically sodium hydroxide, to remove the phytol tail and convert the molecule into a water-soluble form. This transformation enhances bioavailability and improves the ingredient’s solubility for various applications.
- Copper Substitution and Purification: Once the chlorophyll molecule is saponified, a controlled ion-exchange reaction is conducted, where magnesium is replaced with copper ions, forming sodium copper chlorophyllin powder. This step enhances the compound’s stability and antioxidant properties. Advanced purification techniques remove impurities and unreacted components, including filtration and precipitation. High-performance liquid chromatography (HPLC) verifies purity and confirms the copper substitution ratio.
- Drying and Crystallization: The purified sodium copper chlorophyllin is concentrated and dried using spray drying or vacuum drying methods at precisely controlled temperatures to prevent degradation. Crystallization follows, ensuring uniform particle size distribution and improved solubility. Throughout this stage, environmental conditions such as temperature and humidity are carefully monitored to maintain the compound’s structural integrity and potency.
- Quality Control and Packaging: The final product undergoes comprehensive quality testing, including HPLC purity analysis, moisture content verification (≤5%), heavy metal screening, and microbial contamination assessment. Additional testing includes solubility evaluation and pH stability analysis. Once validated, nitrogen-flush is packaged in high-barrier, moisture-resistant containers with desiccant packs to prevent oxidation. Storage conditions require temperatures below 25°C and humidity control below 40%, ensuring a shelf life of up to 36 months.
Referenčný list špecifikácie
Vlastníctvo | Podrobnosti na |
Typ | Food additive |
E Number | E141 |
Vzhľad | Dark green powder |
Čistota | ≥ 95% |
Číslo CAS | 11006-34-1 |
Molekulový vzorec | C34H31CuN4Na3O6 |
Molekulová hmotnosť | 724.16 g/mol |
Rozpustnosť | Highly soluble in water |
Testovacie metódy | UV-Vis, HPLC |
Certifikáty | K dispozícii je ISO. Podrobnosti vám poskytne predajný tím. |
MOQ | 25kg |
Vzorka | K dispozícii (10-20 g/bal) |
Služba OEM | Dostupné na |
Služba ODM | Dostupné na |
Súkromná značka | Dostupné na |
Zmluvná výroba | Dostupné na |
Sodium Copper Chlorophyllin: Benefits, Side Effects, and More
- Antioxidant Properties: It exhibits strong antioxidant properties. It can help neutralize harmful free radicals in the body, potentially reducing oxidative stress. A study published in the Journal of Medicinal Food (2016) demonstrated significant antioxidant activity in vitro.
- Wound Healing: Research suggests that it may promote wound healing. A study in the Journal of Surgical Research (2008) found that it enhanced wound healing in animal models, potentially by stimulating tissue repair and reducing inflammation.
- Anti-Inflammatory Effects: Various studies have shown that it has anti-inflammatory properties. Research published in Inflammation Research (2015) indicated that it could suppress inflammatory responses in cell cultures, suggesting its potential as an anti-inflammatory agent.
- Potential Anti-Cancer Properties: While more research is needed, some studies suggest it may have anti-cancer properties. A review in Nutrition and Cancer (2016) discussed its potential in cancer prevention, highlighting its ability to modulate various cellular pathways involved in carcinogenesis.
- Deodorizing Properties: It is known for its deodorizing properties. A study in the Journal of Dental Research (1951) showed that the ingredient effectively reduced oral malodor, indicating its potential use in oral care products.
- Photosensitizing Agent: It has photosensitizing properties, which could benefit specific applications. Research published in Photodiagnosis and Photodynamic Therapy (2014) explored the use of the compound as a photosensitizer in photodynamic therapy, suggesting potential applications in this field.
Side Effects: Is Sodium Copper Chlorophyllin Safe?
- Mild Digestive Distress: Some individuals may experience nausea or stomach discomfort.
- Citlivosť pokožky: In rare cases, topical application may irritate.
FDA Approval: Is Sodium Copper Chlorophyllin Legal?
- Spojené štáty (FDA): Approved as a food additive a supplement ingredient.
- European Union (EFSA): Permitted as a food colorant and supplement.
- Canada (Health Canada): Recognized as a natural health product.
- Australia (TGA): Allowed in therapeutic and dietary products.
What Is Sodium Copper Chlorophyllin Used For?
- Doplnky stravy: Incorporated for its antioxidant and detoxifying benefits.
- Food Coloring: Used in beverages, confectionery, and processed foods.
- Personal Care: Found in mouthwashes, skin care products, and deodorants.
Dosage Recommendation for Sodium Copper Chlorophyllin
The optimal dosage of Sodium Copper Chlorophyllin depends on its intended use and product formulation. This water-soluble derivative of chlorophyll is widely used in dietary supplements, food colorants, and personal care products due to its antioxidant and deodorizing properties.
- Internal Deodorizing and Digestive Support: A common dosage ranges from 100-300 mg per day, which may help neutralize body odors and support digestive health.
- Antioxidant and Cellular Protection: For oxidative stress reduction, doses of 200-300 mg daily are typically recommended in supplement formulations.
- Topical and Cosmetic Use: When used in personal care products, concentrations of 0.1% to 0.5% are common for skin-soothing and wound-healing applications.
How to Store Sodium Copper Chlorophyllin Powder?
Store this powdered ingredient in an airtight container, away from heat, light, and moisture.
Sodium Copper Chlorophyllin VS Natural Chlorophyll
Sodium copper chlorophyllin and natural chlorophyll are green pigments with similar molecular structures. However, they possess distinct characteristics that are crucial for manufacturers to understand. What is sodium copper chlorophyllin? It is a semi-synthetic derivative of chlorophyll, where the central magnesium ion is replaced with copper, and the phytol tail is removed.
This structural modification results in a water-soluble compound, unlike natural chlorophyll, which is fat-soluble. The enhanced solubility of sodium copper chlorophyllin powder makes it more versatile in various formulations, particularly in aqueous-based products, giving manufacturers greater flexibility in product development.
The stability of these compounds differs significantly, impacting their shelf life and application in different product types. Sodium copper chlorophyllin exhibits superior stability to natural chlorophyll, especially in heat and pH resistance. This stability allows for easier processing and longer shelf life in finished products. Natural chlorophyll, being more sensitive to environmental factors, may require additional stabilization techniques or careful handling during manufacturing. The enhanced stability of sodium copper chlorophyllin powder can be particularly advantageous in products that undergo heat treatment or have a wide pH range.
Color intensity and consistency are important factors for manufacturers to consider. Sodium copper chlorophyllin typically provides a more intense and consistent green color than natural chlorophyll. This characteristic allows for lower usage rates in formulations while still achieving the desired color effect. Natural chlorophyll, while providing a more authentic plant-derived hue, may vary in color intensity depending on its source and extraction method. Manufacturers using sodium copper chlorophyllin can expect more predictable and standardized coloring results across different batches, which is crucial for maintaining product consistency.
The regulatory status and consumer perception of these ingredients also differ. What is sodium copper chlorophyllin in terms of regulatory approval? It is widely recognized as a safe food additive and colorant in many countries, with established acceptable daily intake levels. While generally considered safe, natural chlorophyll may face more regulatory scrutiny depending on its source and extraction method.
However, the natural origin of chlorophyll may be more appealing to consumers seeking “clean label” products. Manufacturers must weigh these factors when choosing between sodium copper chlorophyllin powder and natural chlorophyll, considering their target market preferences and regulatory requirements in different regions. Choosing between these ingredients can significantly impact product positioning, labeling, and marketing strategies in the competitive landscape of green-colored or “natural” products.
| Vlastníctvo | Sodium Copper Chlorophyllin | Natural Chlorophyll |
| Číslo CAS | 11006-34-1 | 479-61-8 |
| Molekulový vzorec | C34H31CuN4Na3O6 | C55H72MgN4O5 |
| Molekulová hmotnosť | ~724.13 g/mol (varies with formulation) | 893.49 g/mol |
| E Number | E141 (Approved Food Additive) | E140 (Approved Food Additive) |
| Powder Color | Dark green to blue-green | Dark green |
| Vzhľad | Fine, water-soluble powder | Oily or waxy, insoluble in water |
| Rozpustnosť | Highly soluble in water | Poorly soluble in water, soluble in organic solvents |
| Stability | More stable under heat, light, and pH variations | Less stable, degrades under heat and light |
| Primary Function | Antioxidant, internal deodorizer, food colorant | Natural pigment, antioxidant, supports detoxification |
| Common Uses | Dietary supplements, food coloring, deodorizing products | Health supplements, natural colorant, detox products |
| Mechanism of Action | Neutralizes free radicals, binds toxins for elimination | Supports oxygen transport and detox pathways |
| Bioavailability | Higher due to water solubility | Lower due to poor water solubility |
| Onset of Action | Rapid absorption in aqueous solutions | Gradual absorption due to lower solubility |
| Advantages | More stable, better absorption, easier formulation | 100% natural, minimally processed |
| Disadvantages | Synthetic derivative, may contain trace metals | Degrades quickly, harder to formulate |
| Other Information | Derived from chlorophyll but with magnesium replaced by copper | Directly extracted from plants like alfalfa and spinach |
Záver
In conclusion, sodium copper chlorophyllin presents a versatile and valuable ingredient for manufacturers across various industries, including food, cosmetics, and pharmaceuticals. What is sodium copper chlorophyllin in terms of its manufacturing potential? It’s a semi-synthetic derivative of chlorophyll that offers enhanced stability, water solubility, and consistent coloring properties compared to its natural counterpart. These characteristics make it attractive for product development, allowing for more straightforward incorporation into various formulations. Manufacturers should consider the unique properties of this compound when developing new products or reformulating existing ones, as it can provide both functional and aesthetic benefits.
The use of the ingredient in manufacturing requires careful consideration of regulatory compliance, as its status and permitted uses may vary across different regions and product categories. Manufacturers working with sodium copper chlorophyllin powder should stay informed about the latest regulatory guidelines and implement rigorous quality control measures to ensure the purity and consistency of their products. Additionally, the growing consumer demand for natural and clean-label products presents challenges and opportunities for using this semi-synthetic colorant.
Manufacturers may need to balance the compound’s technical advantages with market trends and consumer preferences. By leveraging the unique properties of this compound and addressing potential concerns through transparent communication and innovative formulation strategies, manufacturers can develop high-quality, differentiated products that meet regulatory standards and consumer expectations in the evolving marketplace.
About Nutri Avenue
Nutri Avenue is a premier supplier of top-notch quality supplement ingredients, offering a vast selection of amino acids, plant extracts, vitamins, and food additives to support various health formulations. With FDA registration, GMP certification, and Halal, Kosher, and Non-GMO compliance, we guarantee that every ingredient meets the highest safety and quality standards. Our third-party testing process ensures consistent purity, potency, and reliability in every batch.
We provide bulk availability at competitive prices, helping businesses lower costs without compromising quality. Our five USA-based warehouses enable fast and efficient shipping, streamlining supply chains and reducing delays. Additionally, we offer comprehensive Certificates of Analysis (COAs) and dedicated customer support, ensuring a seamless purchasing experience.
Our superb OEM/ODM services allow tailored formulations for brands seeking customization to meet unique market demands. We also supply exclusive trademarked ingredients like Epicatelean® and NutriPQQ®, complete with detailed lab reports and free samples for quality assurance. Whether a startup or an industry leader, Nutri Avenue is your trusted partner for premium ingredients and exceptional service.
* Všetky produkty Nutri Avenue môžu poskytnúť certifikáty ISO.
Často kladené otázky
Sodium copper chlorophyllin is derived from natural chlorophyll, a pigment in plants. However, modifying chlorophyll to create sodium copper chlorophyllin involves chemical reactions, considered semi-synthetic compounds.
Yes, Sodium copper chlorophyllin is water-soluble. It readily dissolves in water, allowing it to incorporate into various water-based products and formulations.
Sodium copper chlorophyllin is generally considered safe for use in approved applications. However, individual sensitivities or allergies may occur, and it is important to follow recommended usage guidelines and consult with a healthcare professional if there are any concerns.
There are no widespread bans on the use of Sodium copper chlorophyllin. However, regulations regarding its use may vary between countries or regions. It is essential to consult the specific rules and guidelines of the relevant authority in your jurisdiction for the most accurate and up-to-date information.
