Vitamin D3 + K2: A Great Supplement Formulation For Bone

Vitamin D3 and Vitamin K2 are important substances for the human body. They participate in the body’s blood coagulation process and help build its immune system. The two functions are different. Vitamin K2 can prevent vitamin D deficiency and treat rickets. Vitamin D3 is mainly used to treat and prevent rickets. There may be questions here. Will the combination of Vitamin D3 + K2 double the effectiveness of calcium supplementation? Let’s start with the benefits of the two vitamins themselves.

Calcium supplementation, whether it is through sunbathing or taking supplements, there are only two results when calcium ions enter the human body. One is that calcium ions are deposited in the correct parts, such as bones, teeth, etc. The other is that calcium ions are deposited in the wrong parts, such as joint cartilage, blood vessels, and kidneys. Under normal circumstances, the calcium ion concentration inside and outside cells maintains a dynamic balance. But when the intracellular calcium ion concentration continues to increase, “calcium deposition” (calcium influx) occurs. Long-term accumulation can cause organ calcification. The most common is vascular calcification. This situation can cause arteriosclerosis, which in turn induces a series of health diseases such as cardiovascular disease.

What Does Vitamin D3 Cholecalciferol Powder Work?

Vitamin D3 needs to go through a series of processes in the body to be converted into the active form – calcitriol – that can exert its effects. Simply put, this process first goes through the liver factory and becomes 25-hydroxyvitamin D3. It then passes through the kidneys and eventually becomes 1,25-dihydroxyvitamin D3 (calcitriol).

The benefits of calcitriol are as follows.

1. It prompts the cells lining the small intestine to produce more calcium-binding protein.
2. It increases calcium absorption in the small intestine.
3. It promotes the biosynthesis of calcium-transporting proteins.
4. It accelerates calcium absorption and increases osteoblast activity.
5. It increases the number of osteoblasts and promotes phosphorus absorption in the small intestine.
6. It stabilizes blood calcium and phosphorus levels, bringing their levels to saturation. Eventually, a density is achieved that maintains appropriate bone density.

What Does MK 7 Vitamin K2 Work?

Vitamin K2 actively guides incorrectly deposited calcium ions into the correct path, that is, human bone tissue, by activating osteocalcin and bone matrix proteins. This process is a key step for “blood calcium” to become “bone calcium.” It can not only reduce the risk of vascular calcification but also prevent the occurrence of cardiovascular diseases. Address osteoporosis at its source. However, the human body cannot synthesize vitamin K2 itself. Healthy intestinal flora can help synthesize vitamin K2.

Vitamin K2 is divided into 14 different forms based on the different carbon atoms in the side chain of the chemical structure. They are structurally similar but have different side chain lengths. The longer the side chain, the better the absorption. And its biological activity will be higher. It will lead to it existing in the blood longer. Therefore, MK 7 Vitamin K2, as a long chain, is the best quality.

In a 3-year controlled trial of the effect MK-7 on bone mineral density in healthy postmenopausal women, Marjo Knapen of Maastricht University in the Netherlands conducted a 3-year study in 2010. In the study, 244 women took a placebo or 180 mg daily. Micrograms of MK 7 Vitamin K2. In the experiment, the levels of uncarboxylated osteocalcin (ucOC) and carboxylated osteocalcin (cOC, also known as γ-carboxyglutamic acid protein) in the serum were measured to determine the effect of vitamin K2.

Research results show that MK-7 supplementation improved vitamin K2 levels in the body. It reduces age-related decline in bone mineral content and density in the lumbar spine and femoral neck. But it won’t affect the buttocks. In addition, daily supplementation with MK 7 Vitamin K2 may also improve bone strength.

Vitamin D3 + K2: How To Work Together?

Judging from the respective roles of vitamins D3 and K2, both play an important role in the process of bone absorption of calcium. But when these two ingredients are combined, the effect is greater than either of these nutrients alone.

First, Vitamin D3 + K2 can enhance the accumulation of osteocalcin. Increased osteocalcin formation significantly improves bone density.

Secondly, Vitamin D3 + K2 increases matrix GLA protein (MGP). MGP protects blood vessels from calcification by accumulating around the elastic fibers in the arterial intima and preventing the deposition of calcium crystals. Moreover, it is currently known as the most effective inhibitor of soft tissue calcification.

Vitamin D3 has more of a dynamic regulatory effect on bones. For the body, in addition to supporting the body, bones also play the role of a “calcium bank.” Vitamin D3, as a hormone, transmits information about body changes and dynamically regulates the distribution of calcium in the blood, bones, and other organs. For example, if a person suffers an accidental fracture, the vitamin D3 in the body will transport calcium from bone A to the fracture site. It is called “reabsorption”. Although this can speed up the recovery of the fracture site, bone A may suffer from osteoporosis in the short term. Therefore, when the level of vitamin D3 is too high, although it will not cause poisoning, it will cause an increase in blood calcium and increase the risk of vascular calcification. In order to avoid this situation, it is recommended to supplement vitamin K2 at the same time as vitamin D3. The function of vitamin K2 on bones is to awaken osteocalcin and help calcium build bones. Among them, the best choice is MK 7 Vitamin K2.

Conclusion

All in all, MK 7 Vitamin K2 helps move calcium from the wrong places into your bones. Vitamin D3 Cholecalciferol Powder can promote the absorption and utilization of calcium. One is responsible for guiding transport, and the other for accelerating absorption. The combination of Vitamin D3 + K2 doubles the effect. Nutri Avenue is very happy to discover this golden combination of calcium supplements and share it with brand customers who want bone health. If you need to order these two raw materials, please choose us.