What Are The Benefits Of St. John Wort Extract?

0.3% Hypericin from the Aerial Parts of St. John Wort Extract Supports Positive Moods, Anti-depression, and Positive Emotional Wellness

What Are The Benefits Of St. John Wort Extract?

St. John Wort Extract is a well-known remedy for various mental health conditions including depression. It contains a compound called Hypericin which is believed by experts to work into the different cells of the body to promote overall well-being. According to studies, St. John Wort Extract may be used to support positive moods and even manage nerve pain.

What is St. John Wort Extract?

Also known as St. Johns Wort Extract, Hypericum perforatum, Saint Johns Wort Extract, and Hypericin Extract, the product St. John Wort Extract is a classic dietary supplement ingredient that is obtained from the flowers and leaves of the herb Hypericum or Hypericum perforatum. During the early days, the said herb is used to produce medicines to treat anxiety, depression, and many other disorders affecting the brain and neurotransmitters. It is also used traditionally for menopause symptoms and other pain disorders.

The product St. John Wort Extract powder has a yellowish to greenish to brownish appearance and is generally soluble in alcohol. It is insoluble in water.

Constituents of St. John Wort Extract

Phytochemical research on St. John Wort Extract reveals that it contains several compounds which contribute to its antidepressant effects. The key ingredients in the product are the naphthodianthrone compounds known as hypericin and Pseudohypericin.

The product also contains relative amounts of phloroglucinols hyperforin and Adhyperforin. Flavonoid compounds may also be obtained from the product. Several other active ingredients including cyclo-pseudo hypericin are hypericin, and Protohypericin may also be found in St. John Wort Extract.


The anthraquinone derivative Hypericin is the key ingredient in St. John Wort Extract which is linked to several health benefits associated with the use of the extract. The compound is found to possess antidepressant, antiviral, and even antineoplastic properties.

The CAS number of the compound Hypericin is 548-04-9 and its molecular formula is C30H16O8. The molecular weight of the same is 504.4 g/mol. Hypericin powder has a yellowish-brown to brownish powder appearance and it is generally soluble in DMSO, ethanol, methanol, and other organic solvents.

Hypericin structure

St. John Wort Extract Forms and Specifications

Some of the common forms of St. John Wort Extract powder include St. John’s wort extract standardized to 0.3% hypericin powder, St. John’s wort 10:1, and 7:1 ratio extract. Some suppliers also offer custom standardized extract forms which customers may avail of for specific formulation needs.

The product St. John Wort Extract may be purchased from legitimate ingredient suppliers like Nutriavenue. Nutriavenue offers bulk purchases or purchases in lesser quantities of products like St. John Wort Extract. In the case of bulk purchases, the product is usually packed in paper drums having two layers of polybags inside. This packaging material is carefully selected to ensure maximum product protection. Nonetheless, Nutriavenue offers other packaging materials which customers may choose from depending on their individual preferences.

How Does St. John Wort Extract Work?

It is believed that the product St. John Wort Extract works by interfering with the production of certain neurotransmitters. In one study, it is found that the product may have actions that are comparatively similar to that of Selective Serotonin Reuptake Inhibitors or SSRIs. In effect, the active ingredients in St. John Wort Extract increase the availability of neurotransmitters including dopamine, serotonin, and norepinephrine.

The compound Hypericin in St. John Wort Extract is also found to help prevent the replication of encapsulated viruses.

St. John Wort Extract Manufacturing Process

St. John Wort Extract is produced using the flowers and leaves of the herb as raw materials. Some of the processes involved in its production are maceration in three different extraction solvents and other extraction procedures.

St. John Wort Extract Health Benefits

Using St. John Wort Extract is ideal for adults in general as it produces various health benefits. These include the following:

  • It helps enhance overall emotional well-being.

By regulating the production of several neurotransmitters in the brain, it is believed that the product St. John Wort Extract may help enhance overall emotional well-being among individual users. Studies reveal that the product helps improve overall mood and prevent rapid mood changes brought about by neurotransmitter and hormonal imbalances.

St John Wort Extract enhances overall emotional wellbeing
  • It may work against depression.

One of the factors causing depression is an irregularity in the production of neurotransmitters dopamine and serotonin. According to experts, the product St. John Wort Extract may help work against depression by preventing rapid decline and imbalances in dopamine and serotonin levels, thereby preventing depression and other mood conditions.

St John Wort Extract work against depression
  • It supports positive moods.

Using St. John Wort Extract also supports a healthy emotional balance and produces a positive mood.

St John Wort Extract supports positive moods
  • It may be used for nerve pain.

Pieces of research also show that the product may be used to reduce nerve pain brought about by various contributory factors. While it may reduce the symptom, there is, however, no proof as to whether the product may treat the underlying conditions causing nerve pain.

St John Wort Extract for nerve pain

St. John Wort Side Effects

Taking dietary supplement products with St. John Wort Extract is claimed to be safe and effective when taken within recommended intakes. Nonetheless, some users may experience mild side effects which usually involve the gastrointestinal system. Users who experience severe adverse reactions affecting vital signs and other organ systems are advised to immediately discontinue the use of the product and seek medical advice.

St. John Wort Extract Dosage

In most studies, the recommended daily intake for St. John Wort Extract is a maximum of 900mg. The product is usually taken three times a day at 300 mg per intake. Physicians may, however, prescribe a different dose depending on the individual user’s weight, age, and overall physical condition. Pregnant and lactating women, as well as those who are taking medications for certain underlying conditions, should consult their physicians before using the product.

Where to Buy St. John Wort Extract Powder in Bulk?

It is best to buy St. John Wort Extract powder in bulk from legitimate and well-known suppliers like Nutriavenue.

Our company, Nutriavenue, is an FDA-registered ingredient supplier which has been in the market of ingredient supply for several years. We are recognized by entities including Halal, Kosher, and GMP.

Aside from St. John Wort Extract powder, we also offer several other ingredients for your dietary supplement formulation needs. You may check out a list of these products from our website and get a free quote. For example:

  • Our main products are PQQ(NutriPQQ®), Epicatechin(Epicatelean®), Alpha-GPC, Phosphatidylserine(PS), and L-Methyfolate.
  • And we have Magnesium Beta Hydroxybutyrate for diabetic patients, strontium citrate for hair loss, marigold extract for eyes, etc.

We also offer shipping services through the air, sea, or couriers like UPS and FedEx. Rates for shipping may vary depending on your location and the weight of the products you purchase.

For more details on our products and services, you may contact our technical support staff.

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