3, 4-divanillyltetrahydrofuran from Nettle Root Extract as a Potent Testosterone Booster

3, 4-divanillyltetrahydrofuran promotes bodybuilding effects

3, 4-divanillyltetrahydrofuran from Nettle Root Extract as a Potent Testosterone Booster

The compound 3, 4-divanillyltetrahydrofuran is among the most popular ingredients in dietary supplements for men as it is proven to increase circulating testosterone levels. In effect, experts say that the compound may be useful in increasing muscle size and promoting body-building efforts. The compound is also believed to improve overall prostate health.

What is 3, 4-divanillyltetrahydrofuran?

More commonly known as Divanil, DVTHF, Stinging Nettle Extract, and Urtica Dioica, 3, 4-divanillyltetrahydrofuran is a lignan that may affect the production of certain hormones in the body involved in the development of secondary sex characteristics. It is believed to be responsible for the various health benefits associated with its plant source Urtica dioica or stinging nettle. The compound is also quite profitable in the bodybuilding industry.

The CAS number of the compound is 34730-78-4 and its molecular formula is C20H24O5. Its molecular weight is 344.4 g/mol. It is described as having a brownish powder appearance.

Constituents of Nettle Root Extract

Nettle Root Extract contains several compounds which contribute to the various health benefits associated with its use. The main key ingredients of the said extract are 6, 7-dihydroxybergamottin and 3, 4-divanillyltetrahydrofuran.

Other compounds found in Nettle Root Extract include the glycoside Beta-sitosterol, and related compounds daucosterol and campesterol, lignans such as (+)-neoolivil, isolariciresinol, and pinoresinol, Chlorogenic Acid, caffeic acid, the anthocyanin pelargonidin, and vitamins like Vitamin C. It also contains vannilic acid and other structurally-related compounds.

3, 4-divanillyltetrahydrofuran forms and specifications

Customers may avail of custom standardized extract form for 3, 4-divanillyltetrahydrofuran. However, the most common form for the said compound in dietary supplement product formulations is 3, 4-divanillyltetrahydrofuran 95% powder.

The product may be purchased from various ingredient suppliers offering services through physical stores or online stores. If you are looking for a legitimate online source for 3, 4-divanillyltetrahydrofuran, it is best to choose reputable companies like Nutriavenue.

3, 4-divanillyltetrahydrofuran may be bought in bulk or lesser quantities from Nutriavenue. In cases of bulk purchases, the compound is usually packed in paper drums with two layers of polybags inside as this packaging option is proven to protect products from damaging elements. You may, however, avail yourself of a different packaging material depending on your individual needs.

How does 3, 4-divanillyltetrahydrofuran work?

Essentially, it is believed that the compound 3, 4-divanillyltetrahydrofuran works by increasing testosterone levels. It does so by occupying binding sites of sex hormone-binding globulin (SHBG) which leads to the reduced ability of the said SHBG to bind steroid hormones. The high affinity of the compound 3, 4-divanillyltetrahydrofuran to SHBG results in an increased concentration of free testosterone.

Also, one study suggested that the compound works by acting upon the enzyme aromatase. Thus, it helps reduce the conversion of testosterone into estrogen.

With all these mechanisms, many manufacturers of bodybuilding dietary supplement products use the compound in their supplement formulations.

3, 4-divanillyltetrahydrofuran Manufacturing Process

One method of producing 3, 4-divanillyltetrahydrofuran is through the use of pulverized heartwoods/roots of T. wallichiana as raw material. The said material is subjected to an extraction procedure with alcohol to obtain an alcoholic extract. The said alcoholic extract is then treated with chlorinated extract solvent. Thereafter, the resulting product is further extraction procedures involving organic solvent. After several extraction procedures, the suitable resulting organic solvent is subjected to crystallization to obtain (-) Secoisolariciresinol. The isolated (-) Secoisolariciresinol is then reacted with triphenylphosphine halide to finally isolate 3, 4-divanillyltetrahydrofuran.

Health benefits of using 3, 4-divanillyltetrahydrofuran

The use of 3, 4-divanillyltetrahydrofuran in dietary supplement products produces the following health benefits:

It is a potent testosterone booster

The compound 3, 4-divanillyltetrahydrofuran has long been found to be a potent testosterone booster. Hence, it is quite beneficial among adult and elderly men who are experiencing bodily changes brought about by the gradual decline in testosterone production. It is also claimed to have positive effects on male sexual health as testosterone levels may affect overall male sexuality. The compound 3, 4-divanillyltetrahydrofuran is said to increase libido among men.

It may be useful for depression

Nettle root extract was used in the early times in the management of depression and anxiety. Based on studies, 3, 4-divanillyltetrahydrofuran is among the compounds in nettle root extract which may have positive effects in improving the overall function of the nervous system, thereby possibly preventing mood disorders such as depression.

It is beneficial for prostate health

Prostate gland health is usually compromised among adult men and those who are approaching the elderly stage. According to researches, stinging nettle which contains 3, 4-divanillyltetrahydrofuran is quite beneficial in reducing urinary complications, specifically, reduced urine flow, brought about by benign prostatic hyperplasia. For the said purpose, the intake of about 120mg of stinging nettle, three times a day is proven to be useful. 

Studies also show that the compound may provide prostate benefits and even possibly reduce prostate size among men suffering from hyperplasia without negatively affecting testosterone production. Instead, it increases testosterone levels while reducing prostate size.

It promotes bodybuilding effects

By increasing testosterone levels, it is believed that 3, 4-divanillyltetrahydrofuran may help promote bodybuilding effects. Thus, it helps reduce body fat while increasing muscle mass. It also helps reduce fatigue and exhaustion while increasing physical body strength. The compound is beneficial not only among athletes and bodybuilders but also among individuals who are seeking to lose weight.

3, 4-divanillyltetrahydrofuran side effects

Essentially, the compound 3, 4-divanillyltetrahydrofuran is claimed to be safe for use. Nonetheless, with its effects in increasing testosterone levels, some health professionals say that individual users may experience slight estrogenic effects. Many manufacturers, however, stack 3, 4-divanillyltetrahydrofuran with other compounds. Thus, the potential light estrogenic effects may be reduced and controlled. Users who experience unusual side effects with 3, 4-divanillyltetrahydrofuran use are advised to immediately consult their physician.

3, 4-divanillyltetrahydrofuran dosage

The recommended dosage for 3, 4-divanillyltetrahydrofuran supplementation may depend on the individual user’s weight, age, and overall physical condition. In most cases, however, health experts recommend the use of about 600 mg per day for the compound 3, 4-divanillyltetrahydrofuran.

Where to buy bulk 3, 4-divanillyltetrahydrofuran powder?

Bulk 3, 4-divanillyltetrahydrofuran powder may be purchased at our company, Nutriavenue.

Nutriavenue is an FDA-registered supplier of various high-quality ingredients at very affordable prices. We offer our products for bulk purchases or purchases in lesser quantities. We have been in the market for several years and we are now recognized by entities like Kosher, GMP, and Halal.

We also offer shipping services through the air, sea, or couriers like UPS and FedEx for your convenience.

If you have any queries on our products and services, you may freely contact our technical support staff.

Share this post with your friends

Get a Free Quote

Stay In Touch

How can we help? Get free samples, pricing and stock list.

USA address
1641 W Main St, Ste 222, Alhambra, CA 91801
China address:
Room 209 , Huana Business Center , NO 1733 Lianhua Road , Minhang District , Shanghai , China 201103

Top Sellers

Nutri Avenue

how can we help ?

Bulk raw Ingredients Supplier

Nutri Avenue

Leave your details below, and let us help you get fresh, high-quality ingredients ASAP.