Is 4-Hydroisoleucine In Fenugreek Seed Powder?

Fenugreek Seed Extract is a potent Testosterone Booster for Male Sexual Health

Is 4-Hydroisoleucine In Fenugreek Seed Powder?

Fenugreek Seed Powder is a popular testosterone booster that has been in the dietary supplement market for several years. It contains a compound known as 4-Hydroisoleucine which helps improve sexual function and increase libido. Fenugreek Seed Extract is also claimed to help normalize blood sugar levels and promote muscle growth and development. Recent studies also show that Fenugreek Seed Extract may provide lactation support among breastfeeding women.

What is Fenugreek Seed Extract?

Fenugreek Seed Extract is a product that is derived from the seeds of the medicinal herb Trigonella Foenum-Graecum. The plant Trigonella Foenum-Graecum has been used in both Ayurvedic and traditional Chinese medicine as an antispasmodic agent, an expectorant, and a treatment for high cholesterol levels. It is also a well-known aphrodisiac and a beneficial condiment.

Fenugreek Seed Extract is sometimes referred to in the field of alternative medicine as FenuTrax, Trigonella Foenum Graecum, Trigonella Foecum-Graecum, Testofen, 50% Fenuside, Libifem, and 4-Hydroxyisoleucine. Fenugreek Seed Extract powder has a creamy yellowish to brown powder appearance and is odorless and tasteless. The powder is generally soluble in water.

Constituents of Fenugreek Seed Powder

There are several active compounds isolated from Fenugreek Seed Extract which are believed to contribute to optimum health and wellness. The key components of the extract are 4-hydroxyleucine and its precursor 2-oxoglutarate, the betaine molecule Trigonelline, Diosgenin, Yamogenin, Protodioscin, and the Trigoneosides Trigofaenoside A and Glycoside D.

Among the fatty acids found in the compound are oleic acid at 16.3%, linoleic acid at 50%, and linolenic acid at 24.4%. It also contains minerals such as potassium, magnesium, calcium, and zinc.


The compound 4-Hydroisoleucine is a non-protein amino acid primarily known for its effects in increasing insulin sensitivity in diabetic patients. The compound is mostly isolated from Fenugreek Seed Extract.

Other names for the compound include L-4-Hydroxyisoleucine and (2S,3R)-2-Amino-4-Hydroxy-3-Methylpentanoic acid. It is also known as having CAS number 781658-23-9 and molecular formula C6H13NO3. Its molecular weight is 147.17 g/mol.

4-Hydroisoleucine structure

Fenugreek Seed Extract Forms and Specifications

Several forms and derivative equivalents of Fenugreek Seed Powder are available in the market for dietary supplement formulations and research purposes. These forms include 20% total saponins, 50% saponins, 65% galactomannan, Furostanol Saponins 50% or 70% UV-VIS, 4-hydroxyleucine 60%, 4-hydroxyleucine 98%, and fermented 4-hydroxyleucine 90%, 95% or 98%. Buyers of the product may also avail of custom standardized extract forms when purchasing from the reputable ingredient supplier Nutriavenue.

At Nutriavenue, the product is mostly packed in paper drums with two layers of poly bags inside when bought in bulk quantities, unless in cases where customers avail of different packaging material. Purchases in smaller quantities may also be availed of by customers.

How does Fenugreek Seed Extract Work?

The prime mechanism of action which is known to Fenugreek Seed Powder is its ability to increase circulating testosterone levels. In this way, the product is believed to enhance overall sexual health among men and produce other benefits associated with the hormone testosterone.

According to research, the compounds Furostanol Glycosides and Saponins which are obtained from the product help increase free testosterone levels by up to 98%. It does so without causing any untoward effects on the body as it is a natural product.

Fenugreek Seed Extract Manufacturing Process

One method to obtain Fenugreek Seed Extract is through the use of Fenugreek seeds as raw material. The fenugreek seeds are mixed with a solvent to allow the components of the Fenugreek seeds to be absorbed by the solvent. The solvent and the Fenugreek seeds are then separated and the former is precipitated into heavy and light phases. The heavy phase is the soluble gum and the light phase is the spent solvent. The soluble gum is then washed and dried.

Fenugreek Seed Powder Health Benefits

The following are some of the health benefits which may be obtained with the use of Fenugreek Seed Extract:

  • It boosts testosterone levels in men.

Testosterone level in men is depleted for various reasons including aging and an unhealthy lifestyle. The use of dietary supplements containing Fenugreek Seed Powder has long been found to increase testosterone levels. Thus, it may be useful not only among elderly men but also among adult males.

Fenugreek Seed Extract boosts testosterone levels
  • It helps improve sexual function and libido.

Among the factors affecting overall sexual function and libido among men is testosterone production. The increase in testosterone brought about by Fenugreek Seed Powder supplementation may help improve sexual function and boost libido, thus improving overall sexual performance.

Fenugreek Seed Extract improve sexual function
  • It supports muscle development and performance.

Men with increased testosterone levels tend to have better performances in physical and extraneous exercises. Thus, it is believed that Fenugreek Seed Powder supplementation may support muscle mass development among men.

Fenugreek Seed Extract supports muscle
  • It helps support lactation.

Lactating women may have reduced milk supply due to numerous factors including stress. According to research, Fenugreek Seed Powder supplementation may increase milk production and supply to meet the baby’s breastfeeding needs.

Fenugreek Seed Extract support lactation
  • It supports normal blood sugar balance.

The intake of the product is also beneficial among diabetics as it helps normalize blood sugar levels, thereby preventing hypoglycemic and hyperglycemic incidents.

Fenugreek Seed Extract supports normal blood sugar balance

Fenugreek Seed Extract Side Effects

Since it is a natural product, there are no serious side effects which are associated with the use of Fenugreek Seed Extract in dietary supplement formulations. Users who experience adverse reactions are advised to immediately consult their physicians, especially when the symptoms involve the cardiovascular or respiratory organ systems.

Fenugreek Seed Extract Dosage

The recommended daily dosage for the use of Fenugreek Seed Extract is 5 to 30 grams. However, the recommended daily intake may vary depending on the individual user’s weight, age, and overall physical condition.

Where to Buy Bulk Fenugreek Seed Extract?

If you are looking for a reputable supplier offering high-quality Fenugreek Seed Extract at very affordable prices, you have come to the right place.

Nutriavenue is an FDA-registered ingredient supplier which has been in the market for several years. It is recognized and certified by entities like Kosher, GMP, and Halal. Aside from Fenugreek Seed Extract, we also offer several other ingredients which you may check out on our website. Our main products are PQQ(NutriPQQ®), Epicatechin(Epicatelean®), Alpha-GPC, Phosphatidylserine(PS), and L-Methyfolate (5-MTHF Ca).

To provide the utmost convenience and service to our customers, we also offer shipping services through the air, sea, or couriers like UPS and FedEx. The rates for shipping vary depending on the weight of the products you purchase and your location.

Should you have any queries on our products and services, feel free to contact our friendly and customer-oriented technical support staff.

Share this post with your friends

Get a Free Quote

Stay In Touch

How can we help? Get free samples, pricing and stock list.

USA address
1641 W Main St, Ste 222, Alhambra, CA 91801
China address:
Room 209 , Huana Business Center , NO 1733 Lianhua Road , Minhang District , Shanghai , China 201103

Top Sellers

Nutri Avenue

how can we help ?

Bulk raw Ingredients Supplier

Nutri Avenue

Leave your details below, and let us help you get fresh, high-quality ingredients ASAP.