Acetyl Zingerone is an antioxidant derived from ginger. It acts as an “all-purpose antioxidant” because of its ability to scavenge and neutralize a wide range of free radicals known to damage the health and appearance of the skin. Today, Nutri Avenue will summarize all the benefits of Acetyl Zingerone for skincare! And we recommend this new ingredient for use in products in all areas of skincare.
Is Acetyl Zingerone The Same As Curcumin?
Many would assume that the two are the same ingredient from the name. However, the structure of curcumin is essentially twice the size of Acetyl Zingerone. However, although Acetyl Zingerone may look like a natural substance, it has undergone a chemical structural modification. As a result, this gives it a much greater ability to fight free radicals. It’s okay to call it Curcumin 2.0.
5 Benefits Of Acetyl Zingerone For Skincare
Studies on human skin and skin cells have shown that Acetyl Zingerone helps counteract the negative effects of environmental damage. It helps to visibly repair and nurture the skin’s ability to maintain extracellular matrix integrity for a healthy appearance.
In addition, it is particularly good at soothing skin exposed to UV rays. Interrupts a range of damage caused by UV rays to the skin’s surface and internal layers. This antioxidant has excellent photostability. In other words, the ingredient stays stable longer when exposed to UV rays.
It reduces mottled pigmentation due to visible spectrum exposure. It means that Acetyl Zingerone protects the skin from visible light (blue or HEV) exposure.
It also has anti-pollution properties, including city dust, which often contains small particles of heavy metals that degrade collagen.
It interrupts the damage to collagen caused by certain enzymes in the skin. From there, Acetyl Zingerone for skincare benefits also include its ability to maintain a youthful appearance longer and help reduce fine lines and wrinkles.
Recognizing Antioxidants: The Body’s Own, Naturally Extracted & Synthetic
As the newest and most versatile antioxidant, the benefits of Acetyl Zingerone for skincare speak for themselves. And many different antioxidant options exist on the market today. Their main two perspectives can be summarized as follows.
- Ingredients inside the body’s antioxidant cycle
Firstly, that part of the ingredient must exclude the enzyme system, as adding enzymes is not feasible inside skincare products.
However, small molecules such as Coenzyme Q10, Vitamin C, Vitamin E, and Lipoic Acid, including the emerging ergothioneine, are great antioxidant options. The body already relies on these ingredients. As we age, the amount of these ingredients in the body gradually decreases. Therefore, choosing skin care products containing ingredients such as ergothioneine is wise.
- The other part is the antioxidant ingredients that are either extracted from nature or synthesized.
It includes Tea Polyphenols, Idebenone, Ferulic Acid, Resveratrol, Curcumin, Astaxanthin, Fullerenes, EUK-134, etc. They are not dominant in the body or even present in the first place. But adding extra is still a nice function.
Acetyl Zingerone VS Vitamins C/E VS Resveratrol VS Astaxanthin
According to Sytheon’s comparative experiment, Acetyl Zingerone for skincare is significantly more potent than Vitamin E and Resveratrol in multiple reactive oxygen species scavenging tests. In terms of its function, it is positioned as a “total free radical killer,” including hydrogen peroxide radicals, hydroxyl radicals, mono-linear oxygen, superoxide radicals, nitric oxide radicals, etc. Each of these antioxidants is only effective against one type of reactive oxygen species.
Each of these antioxidants can only perform well in a few areas. An all-around antioxidant is almost non-existent. However, the ability of Acetyl Zingerone for skincare lies in the fact that it is strong in basically every aspect except for superoxide radicals. It beats vitamin E and resveratrol in almost every other area. It’s also much stronger than the previous tonicol.
For example, while vitamin E is the body’s first line of defense against external attacking free radicals, it’s not as strong in fighting off mono-linear oxygen species or even protecting against sebum peroxide production.
Another natural antioxidant, Astaxanthin, is 6,000 times more powerful than vitamin C at single-linear oxygen. But combined, it’s still about the same as vitamin E.
Acetyl Zingerone activity stays high under UV illumination conditions. Its stability should not be underestimated. Vitamin E and Resveratrol, on the other hand, will basically drop to nothing. Resveratrol, in particular, degrades by 70% in a minute.
The relevant comparative data for Acetyl Zingerone is below.
- It fights off hydrogen peroxide free radicals, 17.7 times more than vitamin E.
- It resists hydroxyl radicals 39.6 times more than vitamin E.
- It fights off nitric oxide free radicals, 126.6 times more than vitamin E.
Data Supporting Acetyl Zingerone For Skincare
Back in 2020, the journal JID (IF=7.0), which is well-known in the field of dermatology, published the results of a genomics experiment. It measured all the genes related to collagen, barrier regeneration, inflammatory factors, and so on. It turns out that Acetyl Zingerone is really quite versatile. It promotes a number of aging-related extracellular matrix glycoproteins and regulatory factors, including collagen regeneration.
JCD also obtained results from a double-blind trial. A 1% product dosage showed significant improvement in wrinkles, skin redness, and pigmentation, with results seen within one month.
Conclusion
In conclusion, Acetyl Zingerone has been studied, from in vitro testing of its antioxidant capacity to cellular experiments to validate some of the indicators related to the skin and, finally, in the clinic. All these verified that the antioxidant capacity of the ingredient is significant in all aspects except for superoxide radicals.
In addition, its chelating function on iron ions (preventing the production of free radicals rather than simply killing them) and its protective function on DNA are still under research. Thus, the potential of this ingredient is very high. The data supporting it is all very fresh.
Nutri Avenue highly recommends that skincare brands recognize this all-purpose oxidant. Acetyl Zingerone for skincare’s capabilities cannot be ignored. It would be a great staple ingredient for brands to launch.
* Due to the policies and maturity of the ingredient, we are offering this ingredient for research use only.
